Results 221 to 230 of about 106,104 (288)

Model-based engineering of Bacillus methanolicus towards de novo polyamine bioproduction from methanol

open access: gold
Luciana Fernandes Brito   +6 more
openalex   +1 more source

Acrolein Promotes Retinal Inflammation Through Macrophage Chemotaxis by Inducing CCL2 Production From Müller Cells

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Patients with proliferative diabetic retinopathy show elevated vitreous levels of the acrolein adduct FDP‐lys and CCL2. In rat Müller glial cells (TR‐MUL5), acrolein increases Ccl2 gene expression and CCL2 secretion and promotes macrophage migration.
Kanae Fukutsu   +4 more
wiley   +1 more source

Simultaneous Grafting of 3,4,5‐Trihydroxypiperidine Iminosugars Onto Multivalent Scaffolds via Double Reductive Amination Provides New GCase Inhibitors

open access: yesChemistry – A European Journal, Volume 32, Issue 2, 9 January 2026.
A small set of low‐valency multivalent 3,4,5‐trihydroxypiperidines was prepared through double reductive amination (DRA) of a sugar‐derived dialdehyde. Among them, trivalent derivative 37 emerged as a potent β‐glucocerebrosidase (GCase) inhibitor displaying an unexpected mixed‐type kinetic profile. The integration of kinetic analysis, NMR, docking, and
Maria Giulia Davighi   +10 more
wiley   +1 more source

Evaluation of agmatine's anti-cancer efficacy in Caco-2 colorectal adenocarcinoma cells. [PDF]

open access: yesMed Oncol
Tanoglu EG   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy