Results 91 to 100 of about 86,841 (327)

Aspirin and glyceryl trinitrate effects on polyamine uptake and smooth muscle cell growth [PDF]

, 2004
This paper looks at aspirin and glyceryl trinitrate effects on polyamine uptake and smooth muscle cell ...
Clarke, Brendan, Grant, M.H., Kelso, K., Wallace, H.M., Winn, P.L.   +4 more
core  

Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder-Robinson syndrome: mechanism of action and therapeutic potential [PDF]

, 2023
Tracy Murray Stewart, Jackson R. Foley, Cassandra E. Holbert, М. А. Хомутов, Noushin Rastkari, Xianzun Tao, Alex R. Khomutov, R. Grace Zhai, Robert A. Casero   +8 more
openalex   +1 more source

Restricting Copper Reconstruction with Ultrathin Polydopamine for Selective and Stable Electrochemical CO2 Reduction Reaction to C2 Products

Advanced Energy and Sustainability Research, EarlyView.
An ultrathin polydopamine coating on copper microcubes mitigates the surface reconstruction during EC‐CO2RR. Copper nanocubes form on the surface of the microcubes in the early stages of the EC‐CO2RR, contributing to suppressed surface reconstruction and sustained Faradaic efficiency for C2 products.
Omran Moradlou, Mohammad Qorbani, Amr Sabbah, Varad Modak, Mengstu Etay Ashebir, Osama Nasr, Chih‐Yang Huang, Fadila Arum Ramadani, Chen‐Hao Wang, Heng‐Liang Wu, Li‐Chyong Chen, Kuei‐Hsien Chen   +11 more
wiley   +1 more source

Theory and simulations of toroidal and rod-like structures in single-molecule DNA condensation

, 2015
DNA condensation by multivalent cations plays a crucial role in genome packaging in viruses and sperm heads, and has been extensively studied using single-molecule experimental methods. In those experiments, the values of the critical condensation forces
Barbi, Maria, Caré, Bertrand R., Cortini, Ruggero, Victor, Jean-Marc   +3 more
core   +2 more sources

Ornithine Decarboxylase mRNA is Stabilized in an mTORC1-dependent Manner in Ras-transformed Cells [PDF]

, 2012
Upon Ras activation, ODC (ornithine decarboxylase) is markedly induced, and numerous studies suggest that ODC expression is controlled by Ras effector pathways. ODC is therefore a potential target in the treatment and prevention of Ras-driven tumours. In
Albig, Barreau, Bhattacharyya, Carracedo, Eulalio, Feith, Feith, Foat, Garneau, Gerner, Grens, Ito, Jacinto, Jian-Ying Wang, Johannes, Kashiwagi, Katsanou, Kawai, Kawai, Kedersha, Kertesz, Lai, Lal, Lan Xiao, Liao, Lisa M. Shantz, Liu, Lorenzini, Manzella, Marderosian, Mazan-Mamczarz, Nowotarski, Origanti, Proud, Rao, Repasky, Rousseau, Sarbassov, Shannon L. Nowotarski, Shantz, Shantz, Sofia Origanti, Song, Suswam, Suzanne Sass-Kuhn, Svitkin, Theresa D. Carr, Tong, Topisirovic, Zhang, Zou, Zou   +51 more
core   +2 more sources

Development and systematic evaluation of triamine‐based functional deep eutectic solvents for efficient CO2 capture

AIChE Journal, EarlyView.
Abstract The development of advanced absorbents for effectively capturing carbon dioxide is crucial in mitigating greenhouse gas emissions. This study introduced a series of deep eutectic solvents (DESs) for CO2 capture and identified the most promising DESs with the stepwise screening method based on their absorption capacity, absorption rate, thermal
Qiangbing Shi, Kaige Jia, Xiangping Zhang, Chuan Wang, Paul Cobden, Anna‐Maria Beregi Amnéus, David Muren, Xiaoyan Ji   +7 more
wiley   +1 more source

Synthetic metallomolecules as agents for the control of DNA structure [PDF]

, 2007
This tutorial review summarises B-DNA structure and metallomolecule binding modes and illustrates some DNA structures induced by molecules containing metallic cations. The effects of aquated metal ions, cobalt amines, ruthenium octahedral metal complexes,
Adair D. Richards, Alessio, Alison Rodger, Baschnagel, Bierbach, Boulikas, Bragg, Brey, Browning, Carle, Chargaff, Clarke, Coggan, den Hartog, Eichhorn, Gale, Gessner, Goodsell, Guschlbauer, Hannon, Hannon, Haq, Hiort, Holliday, Humphrey, Khalid, Laine, Lerman, Lerman, Levitt, Liu, Loprete, Mainwaring, Manzotti, Marrington, Meistermann, Miescher, Molderheim, Neidle, Oleksi, Parkinson, Parkinson, Peberdy, Pelta, Rodger, Rodger, Rodger, Rodger, Rodger, Rosenberg, Sherman, Tabor, Ushay, Watson, Zou   +54 more
core   +1 more source

Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle, Sara M. Sarasua, Tracy Lowe, Christopher L. Farrell, Luigi Boccuto, Charles Schwartz, Anthony E. Pegg, Angela Peron, Victor Faundes, Mythily Ganapathi, Wendy K. Chung, Alban Ziegler, Floris Hofstede, Clément Prouteau, Katharina Steindl, Colleen Olson, Orrin Devinsky, Teresa L. Mastracci, Robert A. Casero Jr., Tracy Murray Stewart, Susan Gilmour, Teri Koerner, Mary Jo Kutler, Surender Rajasekaran, Julianne Michael, André S. Bachmann, Caleb P. Bupp   +26 more
wiley   +1 more source

Zweikanal‐Fluoreszenz‐Assays mit supramolekularen Wirt/Farbstoff‐Reporterpaaren zur Kartierung der Membranaktivität von Peptiden

Angewandte Chemie, EarlyView.
Membranaktive Peptide (MAPs) wie zellpenetrierende Peptide (CPPs) und antimikrobielle Peptide (AMPs) können Lipidmembranen durchdringen und Membranporen bilden. Die Kombination aus einem Farbstoff‐Efflux‐Assay und einem supramolekularen Tandem‐Membran‐Assay in einem Zweikanalformat ermöglicht eine fortgeschrittene mechanistische Charakterisierung und ...
Mohammad A. Alnajjar, Sandra N. Schöpper, Malavika Pramod, Thomas Reingolz, Lina Müller, Justin Neumann, Mohamed Nilam, Werner M. Nau, Andreas Hennig   +8 more
wiley   +1 more source

Dual‐Channel Fluorescence Assays with Supramolecular Host‐Dye Reporter Pairs for Membrane Activity Mapping of Peptides

Angewandte Chemie International Edition, EarlyView.
Membrane‐active peptides (MAPs) such as cell‐penetrating peptides (CPPs) and antimicrobial peptides (AMPs) can translocate across lipid membranes and create membrane pores. The combination of a dye efflux and a supramolecular tandem membrane assay in a dual‐channel format enables an advanced mechanistic characterization and an exploration of the ...
Mohammad A. Alnajjar, Sandra N. Schöpper, Malavika Pramod, Thomas Reingolz, Lina Müller, Justin Neumann, Mohamed Nilam, Werner M. Nau, Andreas Hennig   +8 more
wiley   +1 more source