Results 91 to 100 of about 40,098 (225)

RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis

Advanced Science, EarlyView.
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang, Xiao Li, Shuyue Lei, Qingqing Li, Yi Zhang, Zhizhen Hui, Jinjin Ren, Xuelian Yang, Xiaoqian Yang, Chunlan Feng, Yousheng Xu, Dongxin Zhao, Wei Tang   +12 more
wiley   +1 more source

Senescence and programmed cell death in plants: polyamine action mediated by transglutaminase

Frontiers in Plant Science, 2014
Research on polyamines in plants laps a long way of about 50 years and many roles have been discovered for these aliphatic cations. Polyamines regulate cell division, differentiation, organogenesis, reproduction, dormancy-break and senescence ...
Stefano eDel Duca, Donatella eSerafini-Fracassini, Giampiero eCai   +2 more
doaj   +1 more source

Effects of post-translational modifications catalysed by pollen transglutaminase on the functional properties of microtubules and actin filaments [PDF]

, 2009
TGases (transglutaminases) are a class of calcium-dependent enzymes that catalyse the interactions between acyl acceptor glutamyl residues and amine donors, potentially making crosslinks between proteins.
Bonner, PLR, Cai, G, Cresti, M, Del, Duca, Serafini-Fracassini, D   +4 more
core  

Nanotherapeutic Macrophage‐Neuro Reprogramming Through Immunometabolic Crosstalk Mitigates Sepsis‐Induced Lung Injury and Neurologic Damage

Advanced Science, EarlyView.
SJNPs co‐deliver JHU083 and spermine to reprogram macrophage–neuron immunometabolic crosstalk in sepsis. By suppressing pro‐inflammatory M1 polarization and promoting NGF‐mediated neurotrophic signaling, SJNPs preserve pulmonary neuronal integrity, alleviate lung injury, and improve survival in murine sepsis models.
Wenhui Wang, Yongrui Hai, Xintong Lu, Ye Chen, Bingjie Zhang, Renming Fan, Jiarui Dou, Jiaxin Yan, Shuo Fu, Wen Zhang, Junke Song, Gaofei Wei   +11 more
wiley   +1 more source

Distribution of Polyamines and Responses of Spraying Polyamines in High-Quality Indica Rice Grains

Guangdong nongye kexue
【Objective】The study analyzed the spatial distribution of polyamines in high-quality indica rice grains. The response of spraying of putrescine and spermidine were revealed in two fragrant rice varieties.【Method】Field experimental methods were used to ...
Yangyang PAN, Yibo CHEN, Hong LI, Chongrong WANG, Zhidong WANG, Lei ZHAO, Rong GONG, Jingbo ZHOU, Guorong CHEN, Daoqiang HUANG   +9 more
doaj   +1 more source

Genetic and Phenotypic Features of the Five Known Polyaminopathies: A Critical Narrative Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Polyaminopathies are a recently described family of rare genetic neurodevelopmental disorders. Polyaminopathies disrupt the biosynthesis of the primary polyamines: putrescine, spermidine, and spermine. Snyder–Robinson syndrome results from hemizygous loss‐of‐function variants in the spermine synthase (SMS) gene, resulting in decreased or ...
Elizabeth A. VanSickle, Sara M. Sarasua, Tracy Lowe, Christopher L. Farrell, Luigi Boccuto, Charles Schwartz, Anthony E. Pegg, Angela Peron, Victor Faundes, Mythily Ganapathi, Wendy K. Chung, Alban Ziegler, Floris Hofstede, Clément Prouteau, Katharina Steindl, Colleen Olson, Orrin Devinsky, Teresa L. Mastracci, Robert A. Casero Jr., Tracy Murray Stewart, Susan Gilmour, Teri Koerner, Mary Jo Kutler, Surender Rajasekaran, Julianne Michael, André S. Bachmann, Caleb P. Bupp   +26 more
wiley   +1 more source

Biophysical and biological contributions of polyamine-coated carbon nanotubes and bidimensional buckypapers in the delivery of miRNAs to human cells [PDF]

, 2017
Recent findings in nanomedicine have revealed that carbon nanotubes (CNTs) can be used as potential drug carriers, therapeutic agents and diagnostics tools.
Bordi, Federico, Casciardi, Stefano, Celluzzi, Antonella, D’Oria, Valentina, Masotti, Andrea, Materazzi, Stefano, Paolini, Alessandro, Pezzullo, Marco, Risoluti, Roberta, Sennato, Simona   +9 more
core   +2 more sources

Study on the relationship between the changes in polyamine content and seedless grapes embryo rescue breeding

Frontiers in Plant Science
This study was envisaged to investigate the physiological reasons affecting the embryo development and abortion of seedless grapes on the basis of the previous embryo rescue breeding techniques of seedless grapes.
Guirong Li, Guirong Li, Kaiwei Li, Feifei Han, Huanchao Gao, Ling Wang, Ling Wang   +6 more
doaj   +1 more source

Theory and simulations of toroidal and rod-like structures in single-molecule DNA condensation

, 2015
DNA condensation by multivalent cations plays a crucial role in genome packaging in viruses and sperm heads, and has been extensively studied using single-molecule experimental methods. In those experiments, the values of the critical condensation forces
Barbi, Maria, Caré, Bertrand R., Cortini, Ruggero, Victor, Jean-Marc   +3 more
core   +2 more sources

Chemical Upcycling of Nitrile Butadiene Rubbers to Polyamines and Polyols by Chemoselective Catalytic Hydrogenation

Angewandte Chemie International Edition, EarlyView.
We demonstrate here the transformation of NBR (Nitrile butadiene rubber) including post‐consumer waste sourced from nitrile gloves and o‐rings into polyamines and polyols via ruthenium catalyzed hydrogenation. ABSTRACT We report here two new approaches for the chemical recycling/upcycling of nitrile butadiene rubber (NBR) to make either polyamines or ...
Alejandra Sophia Lozano Perez, Raymundo Marcial‐Hernandez, Harini Sampathkumar, Oluchi Emenike, Ketan Pancholi, Claire N. Brodie, Daniel M. Dawson, Amit Kumar   +7 more
wiley   +1 more source