Results 111 to 120 of about 108,919 (320)

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

Elevated Polyamines in Saliva of Pancreatic Cancer

open access: yesCancers, 2018
Detection of pancreatic cancer (PC) at a resectable stage is still difficult because of the lack of accurate detection tests. The development of accurate biomarkers in low or non-invasive biofluids is essential to enable frequent tests, which would help ...
Yasutsugu Asai   +20 more
semanticscholar   +1 more source

Progress of metabolomics‐centric multi‐omics research in medicine

open access: yesiMetaOmics, EarlyView.
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang   +6 more
wiley   +1 more source

Senescence and programmed cell death in plants: polyamine action mediated by transglutaminase

open access: yesFrontiers in Plant Science, 2014
Research on polyamines in plants laps a long way of about 50 years and many roles have been discovered for these aliphatic cations. Polyamines regulate cell division, differentiation, organogenesis, reproduction, dormancy-break and senescence ...
Stefano eDel Duca   +2 more
doaj   +1 more source

Ionotropic Chemosensory Receptors Mediate the Taste and Smell of Polyamines

open access: yesPLoS Biology, 2016
The ability to find and consume nutrient-rich diets for successful reproduction and survival is fundamental to animal life. Among the nutrients important for all animals are polyamines, a class of pungent smelling compounds required in numerous cellular ...
A. Hussain   +7 more
semanticscholar   +1 more source

The Role and Therapeutic Potential of Voltage‐Gated Potassium Channel Kv1.3 in Metabolism‐Related Disorders

open access: yesiNew Medicine, EarlyView.
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen   +6 more
wiley   +1 more source

Distribution of Polyamines and Responses of Spraying Polyamines in High-Quality Indica Rice Grains

open access: yesGuangdong nongye kexue
【Objective】The study analyzed the spatial distribution of polyamines in high-quality indica rice grains. The response of spraying of putrescine and spermidine were revealed in two fragrant rice varieties.【Method】Field experimental methods were used to ...
Yangyang PAN   +9 more
doaj   +1 more source

Main effects of ascorbic acid levels and organic acid type on physicochemical properties, microbial populations, texture, and biogenic amine formation in sucuk

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Sucuk is a traditional Turkish dry fermented sausage, the quality and safety of which depend on physicochemical, microbiological, and biochemical changes during fermentation and ripening. Organic acids, their salts, and antioxidants such as ascorbic acid (AA) are widely used in fermented meat products; however, information about ...
Gülsüme Bıçakcı, Ömer Eren
wiley   +1 more source

Increased expression of aromatase after focal cerebral ischemia: Relevance to neuroprotection and functional recovery

open access: yesNeuroprotection, EarlyView.
Abstract Aim Aromatase is the key enzyme in the biosynthesis of 17β‐estradiol, the most potent estrogen, which has pleiotropic neuroprotective properties. Aromatase levels increase in the brain after stroke, and its gene variants increase susceptibility to stroke. This study aims to determine whether aromatase overexpression improves stroke outcome and
Lindsay Gallagher   +8 more
wiley   +1 more source

Study on the relationship between the changes in polyamine content and seedless grapes embryo rescue breeding

open access: yesFrontiers in Plant Science
This study was envisaged to investigate the physiological reasons affecting the embryo development and abortion of seedless grapes on the basis of the previous embryo rescue breeding techniques of seedless grapes.
Guirong Li   +6 more
doaj   +1 more source

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