Results 131 to 140 of about 108,919 (320)

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

Phytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

The influence of chemical polyamines analogs, decarboxylated ornithine and s-(adenosyl)-methionine on the polyamine synthsis velocity in test-systems from tissues with high proliferation

RUDN Journal of Medicine, 2010
The aliphatic (amino)- and (oxy)-derivatives of polyamines effect on the rate of polyamines (Putrescine, Spermidine and Spermine) synthesis in cell-free test-systems from rat's regenerating liver and Hepatoma tissues was examined.
S P Siatkin, Т Т Berezov, T V Fedoronchuk, N Yа Gridina, E A Neborakh, N A Shevkhun, N A Sokueva, E V Ustinova, R I Sokuev   +8 more
doaj  

Polyamines function in stress tolerance: from synthesis to regulation

Frontiers in Plant Science, 2015
Plants are challenged by a variety of biotic or abiotic stresses, which can affect their growth and development, productivity, and geographic distribution.
Ji-Hong Liu, Wei Wang, Hao Wu, Xiaoqing Gong, T. Moriguchi   +4 more
semanticscholar   +1 more source

Adverse Aftereffects of Methotrexate as Chemotherapy on Cognitive Deficits in Rat Models [PDF]

, 2020
Patients with acute lymphoblastic leukemia have a high five-year survival rate thanks to methotrexate (MTX). However, cognitive side effects are reported, characterized as chemo brain.
Kang, Jubin
core   +1 more source

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

Increased polyamines alter chromatin and stabilize autoantigens in autoimmune diseases

Frontiers in Immunology, 2013
Polyamines are small cations with unique combinations of charge and length that give them many putative interactions in cells. Polyamines are essential since they are involved in replication, transcription, translation, and stabilization of macro ...
Wesley H. Brooks
doaj   +1 more source

Structural and functional interaction between polyamine related molecules and biological membranes [PDF]

, 2016
La comunicación describe el conocimiento actual sobre las interacciones de biomoléculas relacionadas con el metabolismo de poliaminas con las estructuras y funciones de las membranas biológicasChanges induced by PA on nucleic acid (NA) conformation and ...
Acosta-Andrade, Carlos, Artetxe, I, Fajardo-Paredes, Ignacio José, Goñi, Félix, Lete, MG, Ruiz-Mirazo, Kepa, Sanchez-Jimenez, Francisca Maria, Urdiales-Ruiz, Jose Luis   +7 more
core  

Nickel Foam Electrodes—A Versatile, Powerful, and Readily Available Tool in Electro‐Organic Synthesis

The Chemical Record, EarlyView.
Nickel foam—one material, two faces, and several versatile roles depending on electrolytic conditions. For more than 50 years, nickel foam electrodes have served in electrosynthesis as powerful and readily available electrode materials. Due to their inexpensive nature and easy handling, they have been widely employed.
Rok Narobe, Johannes Schneider, Siegfried R. Waldvogel   +2 more
wiley   +1 more source

In vitro and in vivo studies on exogenous polyamines and α-difluoromethylornithine to enhance bone formation and suppress osteoclast differentiation

Amino Acids
Exogenous polyamines, including putrescine (PUT), spermidine (SPD), and spermine (SPM), and the irreversible inhibitor of the rate-limiting enzyme ornithine decarboxylase (ODC) of polyamine biosynthesis, α-difluoromethylornithine (DFMO), are implicated ...
Chien-Ching Lee, Chia-Chun Chuang, Chung-Hwan Chen, Yuan-Pin Huang, Chiao-Yi Chang, Pei-Yi Tung, Mon-Juan Lee   +6 more
doaj   +1 more source

Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging

Cancer Science, EarlyView.
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka, Shuhei Hirose, Yu Wang, Tomonori Yaguchi, Kenji Chamoto   +4 more
wiley   +1 more source