Results 141 to 150 of about 31,816 (250)

Amino acid metabolism by pig intestinal bacteria and consequences for intestinal health and environment: current knowledge and future directions. [PDF]

J Anim Sci Biotechnol
Blachier F, Tang M, Wu T.
europepmc   +1 more source

Spatially Resolved Metabolomics of Optimal Cutting Temperature (OCT) Compound‐Embedded Tumors

International Journal of Cancer, Volume 159, Issue 12, Page 3038-3048, 15 December 2026.
ABSTRACT Mass spectrometry imaging (MSI) is emerging as a powerful tool for uncovering the distribution of metabolites in the tumor microenvironment and studying tumor metabolism in vivo. To date, MSI of biobanked tissues contextualized by patient data has been limited to peptides, proteins, and glycans—with few examples for metabolites.
Joseph Monaghan, Nicholas Woytowich, Tian Zhao, Kiera Nguyen, Emily Mahony, Julian J. Lum, Kyle D. Duncan   +6 more
wiley   +1 more source

Matrix polyamines regulate bidirectional calcium flux through MCU. [PDF]

Structure
Wang Q, Balderas E, Ramos AJ, Nwafor A, McManus JS, Rai NK, Masini YB, Eberhardt DR, Rekate EC, Balynas AM, Yin X, Stewart TM, Cao E, Stary-Weinzinger A, Chaudhuri D.   +14 more
europepmc   +1 more source

Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy

MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.
Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang, Songhang Xing, Shanshan Zhang, Yuan Hao, Xiaojie Qu, Wurihan Bao, Manwei Hao, Han Sun, Mingyuan Dong, Huiling Zhang, Dan Huang, Yiqi Wang, Xuanjie Jiang, Xiaoyu Pu, Yanyan Chi, Xingtong Wang, Xuefeng Li   +16 more
wiley   +1 more source

Polyamines buffer labile iron to suppress ferroptosis. [PDF]

Cell
Sharma P, Keys HR, Mansell RP, Stark J, Girard L, Ausler C, Anderson R, Müller S, Imada S, Pires IS, Kunchok T, Waite M, Yuan B, Deik A, Ferro L, Hammond PT, Rodriguez R, Pandelia ME, Henry WS, Jain A.   +19 more
europepmc   +1 more source

Plant Identity Shapes Core Microbiomes on Green Roofs

Environmental Microbiology Reports, Volume 18, Issue 6, December 2026.
Three plant species selected from coal mine spoil heaps using a trait‐based approach were associated with distinct bacterial and fungal microbiome patterns in extensive green roof substrates. Discriminant taxa and differences in predicted metabolic pathways provided complementary taxonomic and functional perspectives on plant‐associated substrate ...
Katarzyna Larysz, Michał Ludynia, Artur Trzebny, Wiktoria Klencz, Natalia Malcherczyk, Edyta Sierka   +5 more
wiley   +1 more source

A Novel Polyamine Oxidase from <i>Kluyveromyces marxianus</i> with Potential for Total Polyamine Determination. [PDF]

BioTech (Basel)
Sergeev EP, Atroshenko DL.
europepmc   +1 more source

Peptide‐Linked Bivalent Nanobody Constructs as Positive Allosteric Modulators of the Calcium‐Sensing Receptor

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 6, December 2026.
ABSTRACT We previously developed nanobodies acting as positive allosteric modulators (PAMs) of the calcium‐sensing receptor (CaSR). Here, we sought to develop more potent CaSR modulators by creating bivalent nanobody constructs using ‘tail‐to‐head’ peptide‐linker conjugation.
Mahdis Nabipour, Charlotte Hagen Skadhauge, Line Juel Rasmussen, Hans Bräuner‐Osborne, Jesper M. Mathiesen, Anders A. Jensen   +5 more
wiley   +1 more source

Spermidine in Colorectal cancer: friend or foe? [PDF]

Amino Acids
Coni S, Bordone R, Campea L, Ohno S, Canettieri G, Agostinelli E.   +5 more
europepmc   +1 more source

Plant NAOGAT (ArgJ) Structure Reveals Mechanism of Ornithine Biosynthesis, Preference for Acetylornithine and Susceptibility to Mangotoxin

Plant, Cell &Environment, Volume 49, Issue 12, Page 10283-10300, December 2026.
ABSTRACT Arginine metabolism in plants is targeted by phytopathogens such as Pseudomonas syringae strains, which produce toxins that affect enzymes of plant arginine metabolism, causing devastating infections in crops. In this work, the structural and functional properties of plant N‐acetylornithine glutamate acetyltransferase (NAOGAT), the key ...
Maciej Nielipinski, Agnieszka J. Pietrzyk‐Brzezinska, Aleksandra Twarda‐Clapa, Bartosz Sekula   +3 more
wiley   +1 more source