Results 161 to 170 of about 31,816 (250)

IL-9R/Arg1 pathway promotes polyamine metabolism in human airway macrophages. [PDF]

J Allergy Clin Immunol
Zhang W, Cheon IS, Pajulas A, Sinn AL, Krishnan MS, Zhang J, Abdelaal AM, Liu X, Jackson KG, Zhang J, Pollok KE, Kloepfer KM, Twigg HL, Gaston B, Teague WG, Sun J, Kaplan MH.   +16 more
europepmc   +1 more source

GABAergic Network Dysregulation in Alcohol Use Disorder: Receptor–Transporter Interactions Driving the Transition From Goal‐Directed to Compulsive Behaviour

Addiction Biology, Volume 31, Issue 11, November 2026.
Astrocytic GAT3 regulates ambient GABA levels in the globus pallidus externus (GPe). Reduced GAT3 function enhances extrasynaptic GABAergic signalling and disrupts subthalamic nucleus (STN) regulation and cortical signal fidelity.ABSTRACTAlcohol use disorder (AUD) is characterized by a shift from controlled, goal‐directed drinking to compulsive ...
Hannah Aranda, Nathan Jones, Humza Haroon, Doo‐Sup Choi   +3 more
wiley   +1 more source

Spermine Synthase at the Polyamine-Redox Interface: Mechanistic Evidence from Snyder-Robinson Syndrome and Cancer. [PDF]

Antioxidants (Basel)
Lin Z, Lin Y, Li M, Zhan S, Xu Q, Yu F.
europepmc   +1 more source

Methionine Regulates Antitumour Function of CD8+ T Cells Through Polyamine Synthesis

Immunology, Volume 179, Issue 3, Page 418-433, November 2026.
Methionine restriction in vitro enhances CD8+ T cell effector function by suppressing polyamine synthesis and progressively induces the co‐expression of PD‐1 and TIM‐3. Consistently, sustained dietary methionine restriction diminishes the efficacy of adoptive T cell therapy (ACT) and promotes the expression of terminal exhaustion‐associated markers ...
Tian Zhao, Gillian A. Carleton, Sam Preshaw, Sarah MacPherson, Madison Shiyuk, Joseph Monaghan, Jun Han, Oro Uchenunu, Robert Rottapel, Ralph J. DeBerardinis, Kelly M. Stewart, Bo‐Hyun Kim, Juan Ausió, David R. Goodlett, Helena Pětrošová, Kyle D. Duncan, Julian J. Lum   +16 more
wiley   +1 more source

Tomato Yellow Leaf Curl Virus Reprograms Polyamine Metabolism in <i>Bemisia tabaci</i> MED to Enhance Viral DNA Accumulation. [PDF]

Molecules
Sang Z, Han H, Qi F, Pan G, Zhang G, Qiu S, Wei Y, Zhang Z, Zhang H, Xia J.   +9 more
europepmc   +1 more source

Tracking Sodium Inside the Plant: Hydraulic Adjustments to Deal With Salinity

Journal of Agronomy and Crop Science, Volume 212, Issue 6, November 2026.
ABSTRACT Sorghum is a crop that has become more relevant in recent years due to its uses and properties (biofuel, gluten‐free flour) as well as its versatility to grow in unfavourable environmental conditions. Salinity is one of the main abiotic stresses affecting crop production and yield worldwide.
Moira R. Sutka, Pablo D. Cáceres, Marina Recchi, Andrea S. Dengis, Milena E. Manzur   +4 more
wiley   +1 more source

Accelerating Phosphate Transport Across Membranes via Synergistic Chemical‐Electrochemical Carriers

Angewandte Chemie, Volume 138, Issue 43, 19 October 2026.
A new membrane design principle based on synergistic chemical and electrochemical carriers is proposed to construct an electro‐driven carrier‐conducting membrane for high‐throughput phosphate transport. Monodispersed ferrihydrite nanoparticles embedded within the membrane act as built‐in phosphate carriers, enabling accelerated phosphate migration via ...
Lei Xia, Yangbo Qiu, Qingzhi Liu, Mengjiao Guan, Xi Zhang, Raf Dewil, Jin Shang, Yan Zhao, Bart Van der Bruggen, Chuyang Tang   +9 more
wiley   +2 more sources

Separating extracellular from intracellular fecal metabolites exposes cross-feeding architecture in the gut: exploring metabolite partitioning and ecological associations. [PDF]

Gut Microbes
Hirayama M, Takame F, Maeda T, Kashihara K, Ito M, Ohno K, Ueyama J.   +6 more
europepmc   +1 more source

Genomic variation drives plant flavor diversification

Journal of Integrative Plant Biology, Volume 68, Issue 11, Page 3895-3913, November 2026.
This review explains how genomic variation shapes plant flavor by altering the biosynthetic and regulatory pathways of key attributes like sweetness, acidity, bitterness, piquancy, astringency, and aroma. It also discusses how multi‐omics, AI‐assisted breeding, and gene editing can translate this knowledge into plants with improved flavor, nutrition ...
Huimin Hu, Yanwei Hao, Yiwei Zhou, Xia Zhang, Rui Xia, Pan Liao   +5 more
wiley   +1 more source

Polyamines as Gatekeepers of Virus Replication and Central Nervous System Homeostasis. [PDF]

Pathogens
Stacey SP, Mounce BC.
europepmc   +1 more source