Heavy water labeling reveals metabolic flexibility of amino acid and polyamine pathways in mammalian cells. [PDF]
Gonzalez-Ibarra A +10 more
europepmc +1 more source
1. Spatiotemporal multi‐omics atlas reveals regional metabolic and proteomic specificity during sepsis‐to‐S‐AKI progression. 2. Arginine metabolism is central to S‐AKI pathogenesis, with declining arginine levels correlating with worsening renal function. 3. ARG2 upregulation in renal tubules and macrophages drives tubular lipid accumulation and kidney
Yu Xin +23 more
wiley +1 more source
Polyamine-mediated inhibition of ferroptosis contributes to geroprotection. [PDF]
Madeo F, Carmona-Gutierrez D, Kroemer G.
europepmc +1 more source
Alterations in Arginase Activity and Polyamine Metabolism Contribute to the Mode of Action of Canavanine in Tomato Roots. [PDF]
Staszek P, Ciacka K, Gniazdowska A.
europepmc +1 more source
The molecular mechanisms contributing to impaired fertility in HIV+ males remain poorly defined. Using a human immunodeficiency virus (HIV) transgenic (Tg) rat model, we demonstrate key structural and functional sperm regulators including cation channel of sperm (CatSper)1–4 channels and mitochondrial biogenesis genes were markedly downregulated ...
Tousif Ahmed Hediyal +12 more
wiley +1 more source
Probiotic and microbial modulation of polyamine production: an emerging avenue for neuroprotection in neurodegenerative disorders. [PDF]
Adhikari T, Saha P.
europepmc +1 more source
ABSTRACT Thousand‐grain weight (TGW) is a critical determinant of grain yield in foxtail millet. To elucidate the molecular regulatory network governing this trait, we systematically evaluated the main agronomic traits and genetic diversity of 40 core germplasm accessions, aiming to identify elite genetic resources.
Wei Zhang +3 more
wiley +1 more source
Translational Entropy-Driven Competitive and Additive Effects on DNA Higher-Order Structure via Ion Exchange Between Cations of Different Valencies. [PDF]
Kenmotsu T +3 more
europepmc +1 more source
This graphical abstract compares four fermentation strategies for D. nobile rice wine: simultaneous inoculation without D. nobile (SW), simultaneous inoculation with D. nobile (DnSW), sequential inoculation without D. nobile (WS), and sequential inoculation with D. nobile (DnWS). Simultaneous inoculation (SW/DnSW) enhanced volatile compound content (up
Hongling Gan +7 more
wiley +1 more source
Spermine suppresses <i>Salmonella</i>-induced macrophage innate immune responses via inhibition of the cGAS-STING and TLR4 pathways. [PDF]
Wang X +10 more
europepmc +1 more source

