Results 71 to 80 of about 451,989 (311)

Phosphoprotein enriched in astrocytes (PEA)-15 : A potential therapeutic target in multiple disease states [PDF]

, 2014
Copyright © 2014 Elsevier Inc.
Greig, Fiona H, Nixon, Graeme F
core   +1 more source

PKD1-associated autosomal dominant polycystic kidney disease with glomerular cysts presenting with nephrotic syndrome caused by focal segmental glomerulosclerosis

BMC Nephrology, 2019
Background Autosomal dominant polycystic kidney disease (ADPKD) may manifest non-nephrotic range proteinuria, but is rarely complicated with nephrotic syndrome.
Yasuhiro Oda, Naoki Sawa, Eiko Hasegawa, Hiroki Mizuno, Masahiro Kawada, Akinari Sekine, Rikako Hiramatsu, Masayuki Yamanouchi, Noriko Hayami, Tatsuya Suwabe, Junichi Hoshino, Kenmei Takaichi, Keiichi Kinowaki, Kenichi Ohashi, Takeshi Fujii, Yoshifumi Ubara   +15 more
doaj   +1 more source

Gpr48 deficiency induces polycystic kidney lesions and renal fibrosis in mice by activating Wnt signal pathway.

PLoS ONE, 2014
G protein-coupled receptor 48 (Gpr48/Lgr4) is essential to regulate the development of multiple tissues in mice. The notion that Gpr48 functions in renal development prompted us to investigate the relation between Gpr48 and renal diseases.
Yongyan Dang, Bei Liu, Peng Xu, Pingya Zhu, Yimiao Zhai, Mingyao Liu, Xiyun Ye   +6 more
doaj   +1 more source

Infectious Diseases Associated With Renal Homotransplantation: I. Incidence, Types, and Predisposing Factors [PDF]

, 1964
Infectious diseases occurred in 26 of 30 renal homotransplantation patients and contributed to eight of the 12 deaths in this series. There were 52 infections, 17 occurring before and 35 after transplantation.
Marchioro, TL, Rifkind, D, Starzl, TE, Waddell, WR   +3 more
core   +1 more source

Congenital hepatic fibrosis and its mimics: a clinicopathologic study of 19 cases at a single institution

Diagnostic Pathology, 2021
Background Congenital hepatic fibrosis (CHF) is a rare inherited form of ductal plate malformation associated with polycystic kidney disease. The diagnosis requires histopathologic confirmation, but can be challenging to distinguish from other undefined ...
Irene Y. Chen, Christa L. Whitney-Miller, Xiaoyan Liao   +2 more
doaj   +1 more source

c-Jun N-terminal kinase (JNK) signaling contributes to cystic burden in polycystic kidney disease.

PLoS Genetics, 2021
Polycystic kidney disease is an inherited degenerative disease in which the uriniferous tubules are replaced by expanding fluid-filled cysts that ultimately destroy organ function.
Abigail O Smith, Julie A Jonassen, Kenley M Preval, Roger J Davis, Gregory J Pazour   +4 more
doaj   +1 more source

Stem cells and fluid flow drive cyst formation in an invertebrate excretory organ.

, 2015
Cystic kidney diseases (CKDs) affect millions of people worldwide. The defining pathological features are fluid-filled cysts developing from nephric tubules due to defective flow sensing, cell proliferation and differentiation.
Alexander, R., Alvarado, A., Lakshmanaperumal, N., McClain, M., McKinney, S., Rink, J., Vu, H.   +6 more
core   +1 more source

Renal replacement therapy in ADPKD patients : a 25-year survey based on the Catalan registry [PDF]

, 2013
Background: Some 7-10% of patients on replacement renal therapy (RRT) are receiving it because of autosomal dominant polycystic kidney disease (ADPKD). The age at initiation of RRT is expected to increase over time.
Arcos, Emma, Ars Criach, Elisabet, Ballarín Castan, José Aurelio, Cabezuelo, Juan, Comas, Jordi, Díaz Gómez, Joan Manuel, Martínez, Víctor, Muray, Salomé, Torra Balcells, Roser   +8 more
core   +1 more source

Radiographic Imaging in Autosomal Dominant Polycystic Kidney Disease: A Claims Analysis

International Journal of Nephrology and Renovascular Disease, 2021
Myrlene Sanon Aigbogun,1 Robert A Stellhorn,1 Christina S Pao,1 Stephen L Seliger2 1Otsuka Pharmaceutical Development & Commercialization, Inc, Princeton, NJ, USA; 2University of Maryland School of Medicine, Baltimore, MD, USACorrespondence: Stephen ...
Sanon Aigbogun M, Stellhorn RA, Pao CS, Seliger SL   +3 more
doaj  

Kidney segmentation using 3D U-Net localized with Expectation Maximization [PDF]

, 2020
Kidney volume is greatly affected in several renal diseases. Precise and automatic segmentation of the kidney can help determine kidney size and evaluate renal function. Fully convolutional neural networks have been used to segment organs from large biomedical 3D images.
arxiv   +1 more source