Results 71 to 80 of about 36,402 (277)

Autophagy in Chronic Kidney Diseases

Cells, 2019
Autophagy is a cellular recycling process involving self-degradation and reconstruction of damaged organelles and proteins. Current evidence suggests that autophagy is critical in kidney physiology and homeostasis.
Tien-An Lin, Victor Chien-Chia Wu, Chao-Yung Wang   +2 more
doaj   +1 more source

A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease

Acta Ophthalmologica, EarlyView.
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia, José Manuel Benítez del Castillo, Margarita Calonge, Christophe Baudouin, Marc Labetoulle   +4 more
wiley   +1 more source

Axial Spondyloarthritis and Autosomal Dominant Polycystic Kidney Disease in Two Siblings: A Rare Cooccurrence

Case Reports in Rheumatology, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequently occurring hereditary kidney disease, and axial spondyloarthritis (SpA) is one of the most frequently occurring rheumatic diseases.
Ozan Volkan Yurdakul, Abdulkerim Furkan Tamer, Okan Küçükakkaş, Aylin Rezvani   +3 more
doaj   +1 more source

Effect of Renal Denervation on Early and Late Stages of Diabetic Nephropathy. [PDF]

FASEB J
This graphical abstract illustrates how renal denervation decreases the mean arterial blood pressure in the young but not old T2DN rats independent of improved glucose handling and kidney function of both young and old T2DN rats. ABSTRACT Diabetic kidney disease (DKD) is a major driver of morbidity and mortality worldwide. Although the FDA has recently
Xu B, Lowe M, Levchenko V, Morales MN, Klemens CA, Banek CT, Staruschenko A.   +6 more
europepmc   +2 more sources

Apoptosis in polycystic kidney disease

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2011
Apoptosis is the process of programmed cell death. It is a ubiquitous, controlled process consuming cellular energy and designed to avoid cytokine release despite activation of local immune cells, which clear the cell fragments. The process occurs during organ development and in maintenance of homeostasis.
openaire   +3 more sources

Robot‐assisted vs open kidney transplantation from deceased donors

BJU International, EarlyView.
Objectives To test the hypothesis that the type of surgical approach, robot‐assisted kidney transplantation (RAKT) vs open kidney transplantation (OKT), impacts intra‐operative and postoperative surgical outcomes of patients receiving kidney transplantation from deceased donors.
Luca Afferi, Angelo Territo, Alessio Pecoraro, Lorenzo Masieri, Milla Ortved, Julia Abildgaard Dagnæs‐Hansen, Begonya Etcheverry, Andrea Gallioli, Donato Cannoletta, Joris Vangeneugden, Jeremy Mercier, Thomas Prudhomme, Isacco Donnini, Antonino Vazzana, Malene Rohrsted, Francesc Vigués, Nicolas Doumerc, Karel Decaestecker, Joan Palou, Riccardo Campi, Sergio Serni, Andreas Roder, Alberto Breda   +22 more
wiley   +1 more source

Renal cell carcinoma in a cat with polycystic kidney disease undergoing renal transplantation

Journal of Feline Medicine and Surgery Open Reports, 2018
Case summary A 10-year-old spayed female American Shorthair cat underwent renal transplantation due to worsening chronic kidney disease secondary to polycystic kidney disease.
Daniel J Adams, Jolie A Demchur, Lillian R Aronson   +2 more
doaj   +1 more source

Molecular Diagnosis and Identification of Novel Pathogenic Variants in a Large Cohort of Italian Patients Affected by Polycystic Kidney Diseases. [PDF]

Genes (Basel), 2023
Nigro E, Amicone M, D'Arco D, Sellitti G, De Marco O, Guarino M, Riccio E, Pisani A, Daniele A.   +8 more
europepmc   +1 more source

Discovery of natural product derivative triptolidiol as a direct NLRP3 inhibitor by reducing K63‐specific ubiquitination

British Journal of Pharmacology, EarlyView.
▪ Background and Purpose NLRP3 is up‐regulated in inflammatory and autoimmune diseases. The development of NLRP3 inhibitors is challenged by the identification of compounds with distinct mechanisms of action avoiding side effects and toxicity. Triptolide is a natural product with multiple anti‐inflammatory activities, but a narrow therapeutic window ...
Mo‐Yu Ding, Chengqing Ning, Shao‐Ru Chen, Hao‐Ran Yin, Jing Xu, Ying Wang   +5 more
wiley   +1 more source

Insights Into the Molecular Mechanisms of Polycystic Kidney Diseases. [PDF]

Front Physiol, 2021
Vasileva VY, Sultanova RF, Sudarikova AV, Ilatovskaya DV.   +3 more
europepmc   +1 more source