Results 21 to 30 of about 33,171 (260)

Hereditary hemochromatosis and JAK2‐positive polycythemia vera

Clinical Case Reports, 2021
A 59‐year‐old man was diagnosed with JAK2‐positive polycythemia vera. Subsequently, further laboratory testing revealed elevated ferritin and iron saturation.
Ahmed Radwan, Ibraheem Othman
doaj   +1 more source

Double Thrombosis- Interesting Case of Polycythemia Vera [PDF]

Journal of Clinical and Diagnostic Research, 2020
Polycythemia vera is a myeloproliferative disorder which has a varied manifestation, one of it being venous thrombosis and arterial thrombosis which significantly contributes to the mortality and morbidity.
Subashini Subramanian, Siva Ranganathan Green   +1 more
doaj   +1 more source

Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera.

PLoS ONE, 2020
The myeloproliferative neoplasms, polycythemia vera, essential thrombocytosis and primary myelofibrosis are hematopoietic stem cell disorders and share driver mutations that either directly activate the thrombopoietin receptor, MPL, or activate it ...
Jerry L Spivak, Akil Merchant, Donna M Williams, Ophelia Rogers, Wanke Zhao, Amy Duffield, Linda S Resar, Alison R Moliterno, Zhizhuang J Zhao   +8 more
doaj   +1 more source

Neutrophil-to-Lymphocyte ratio as surrogate for JAK2^V617F suppression and event-free survival in polycythemia vera. [PDF]

Blood Cancer J
Barbui T, Ghirardi A, Empson V, Fenili F, Loscocco GG, Condorelli A, Iurlo A, Cattaneo D, Rossi E, De Stefano V, Guglielmelli P, Klade C, Gisslinger H, Rambaldi A, Scandura JM, Vannucchi AM.   +15 more
europepmc   +3 more sources

Familial polycythemia vera

Cleveland Clinic Journal of Medicine, 1989
The occurrence of polycythemia vera in a father, mother, and two sons is reported. Thirteen kindreds with familial polycythemia vera in 31 members are reviewed. Comprehensive records were available for all four patients as well as other family members, since all were diagnosed and treated at the author's institution over a period of nearly 50 years ...
R L, Miller, J D, Purvis, J K, Weick
openaire   +2 more sources

Macrophages support pathological erythropoiesis in Polycythemia Vera and Beta-Thalassemia [PDF]

, 2014
Regulation of erythropoiesis is achieved by integration of distinct signals. Among these, macrophages are emerging as erythropoietin-complementary regulators of erythroid development, particularly under stress conditions. We investigated the contribution
Abdel-Wahab, Omar, Breda, Laura, Casu, Carla, Crielaard, Bart J., Ebert, Benjamin L., Gardenghi, Sara, Ghaffari, Saghi, Giardina, Patricia J., Grady, Robert W., Gupta, Ritama, Guy, Ella, Levine, Ross L., Marongiu, Maria Franca, Ramos, Pedro, Rivella, Stefano, Van Rooijen, Nico   +15 more
core   +1 more source

The JAK2V617 mutation induces constitutive activation and agonist hypersensitivity in basophils from patients with polycythemia vera

Haematologica, 2009
Background The JAK2V617F mutation has been associated with constitutive and enhanced activation of neutrophils, while no information is available concerning other leukocyte subtypes.Design and Methods We evaluated correlations between JAK2V617F mutation ...
Lisa Pieri, Costanza Bogani, Paola Guglielmelli, Maria Zingariello, Rosa Alba Rana, Niccolò Bartalucci, Alberto Bosi, Alessandro M. Vannucchi   +7 more
doaj   +1 more source

Erythematous Macular Eruption in an Older Woman [PDF]

, 2019
A white woman in her 70s with advanced Alzheimer disease was referred to the hematology clinic for evaluation of a high hemoglobin level (169 g/L; normal range, 120-160 g/L) and red blood cell count (5.67 × 1012/L; normal range, 3.8-4.8 × 1012/L) as well
Kernohan, Neil, McLaughlin, David, Tauro, Sudhir   +2 more
core   +2 more sources

Neutropenia caused by hairy cell leukemia in a patient with myelofibrosis secondary to polycythemia vera: a case report

Journal of Medical Case Reports, 2018
Background Polycythemia vera is a myeloproliferative disease that sometimes evolves to myelofibrosis, causing splenomegaly and neutropenia. In this case report, we describe a patient with polycythemia vera and unexplained neutropenia who later turned out
Andreas Hanssønn Habberstad, Hoa Thi Tuyet Tran, Ulla Randen, Signe Spetalen, Ingunn Dybedal, Geir E. Tjønnfjord, Anders Erik Astrup Dahm   +6 more
doaj   +1 more source

Preleukemia: hematological disorders prior to onset of leukemia [PDF]

, 1975
Published data on Japanese leukemia patients with a preleukemic hematological disorder were assessed. The reexamined cases were from the "Japona Centra Revuo Medicina" reported during the period from 1952 to 1971.
Hiraki, Kiyoshi, Kitajima, Koichi, Mikochi, Hiroshi, Nakanishi, Toshio, Sakato, Junya, Takahashi, Isao   +5 more
core   +1 more source