Refractory Alopecia Areata of the Beard: Novel Improvement Through Exosome Therapy With Signs of Hair Repigmentation [PDF]
Clinical Case ReportsExosome injections derived from human umbilical cord, with or without polydeoxyribonucleotide, induced robust regrowth, repigmentation of previously white beard hairs, and scar improvement in a 35‐year‐old man with refractory alopecia areata of the beard,
Asem Shadid +4 more
doaj +3 more sources
Molecules, 2023 Polydeoxyribonucleotide (PDRN) has the ability to regenerate skin cells and improve the skin barrier and wound healing. This study investigated the possibility of replacing animal-derived PDRN with plant-derived PDRN. To test this, the adventitious roots
Kwang-Soo Lee +7 more
exaly +3 more sources
Polydeoxyribonucleotide Ameliorates Inflammation and Apoptosis in Achilles Tendon-Injury Rats [PDF]
International Neurourology Journal, 2020 Purpose Adenosine A2A receptor agonist polydeoxyribonucleotide (PDRN) possesses an anti-inflammatory effect and suppress apoptotic cell death in several disorders.
Jeong Ho Rho +7 more
doaj +4 more sources
Polydeoxyribonucleotide Dermal Infiltration in Male Genital Lichen Sclerosus: Adjuvant Effects during Topical Therapy [PDF]
Dermatology Research and Practice, 2013 Background. Lichen sclerosus (LS) is an autoimmune inflammatory skin disease that leads to tissue sclerosis. Actually, the first-line treatment consists of local steroid as clobetasol propionate (CP).
Luigi Laino +2 more
doaj +3 more sources
Marine Drugs, 2019 Bisphosphonates (BPs) used for treating skeletal diseases can induce bisphosphonate-related osteonecrosis of the jaw (BRONJ). Despite much effort, effective remedies are yet to be established.
Deok-Won Lee +2 more
exaly +3 more sources
Polydeoxyribonucleotide-delivering therapeutic hydrogel for diabetic wound healing [PDF]
Scientific Reports, 2020 Patients with diabetes experience delayed wound healing because of the uncontrolled glucose level in their bloodstream, which leads to impaired function of white blood cells, poor circulation, decreased production and repair of new blood vessels ...
Da Yong Shin +5 more
doaj +3 more sources
Scar Prevention and Enhanced Wound Healing Induced by Polydeoxyribonucleotide in a Rat Incisional Wound-Healing Model [PDF]
International Journal of Molecular Sciences, 2017 High-mobility group box protein-1 (HMGB-1) plays a central role in the inflammatory network, and uncontrolled chronic inflammation can lead to excessive scarring.
Woonhyeok Jeong +2 more
exaly +3 more sources
Oral and Intranasal Administration of Polydeoxyribonucleotide Isolated from Porphyra sp. Ameliorates Acute Lung Injury via Suppressing Proinflammatory Cytokine Production in Mice [PDF]
Current Issues in Molecular BiologyAcute lung injury (ALI) is a severe inflammatory condition with high mortality rates, necessitating the development of effective therapeutic agents. Polydeoxyribonucleotide (PDRN), a DNA-derived compound known for its tissue repair and anti-inflammatory ...
Ga-Young Lee +3 more
doaj +2 more sources
Ultrasound-Guided Pharmacopuncture for Lateral Epicondylitis Initially Misdiagnosed Due to Incomplete Common Extensor Tendon Evaluation: a case report [PDF]
Journal of PharmacopunctureLateral epicondylitis is a common musculoskeletal condition caused by repetitive strain, most frequently affecting the extensor carpi radialis brevis (ECRB) muscle.
Taeseok Ahn +9 more
doaj +2 more sources
Guang Chenpi Extract as a Multifunctional Phytotherapeutic: Enhanced Effects with Ergothioneine and Polydeoxyribonucleotide on Redox Homeostasis and Tissue Resilience [PDF]
PharmaceuticalsBackground/Objectives: Guang Chenpi, the aged pericarp of Citrus reticulata ‘Chachi’, is a traditional Chinese medicinal food with documented health benefits.
Zongxiao Cen +6 more
doaj +2 more sources