Results 231 to 240 of about 35,820 (275)

Palladium/polyethylenimine catalysts

Journal of Molecular Catalysis, 1985
Abstract We report the preparation and evaluation of palladium catalysts made from polyethylenimine (PEI)/silica composites. PEI was adsorbed to either porous silica beads or silica gel. Following crosslinking, the material was leached with base to increase the surface area and availability of the polymer.
G.P. Royer, Wen-Shiung Chow, Kimi S. Hatton   +2 more
openaire   +1 more source

Efficient Gene Delivery into Human Dendritic Cells by Adenovirus Polyethylenimine and Mannose Polyethylenimine Transfection

Human Gene Therapy, 1999
Gene-modified human dendritic cells (DCs) were generated by transfection with adenovirus polyethylenimine DNA (Ad/PEI/DNA) and mannose polyethylenimine DNA (ManPEI/DNA) complexes. Ad/PEI/DNA complexes have plasmid DNA bound to adenovirus particles by PEI and deliver DNA into cells via the adenovirus infection route.
S S, Diebold, H, Lehrmann, M, Kursa, E, Wagner, M, Cotten, M, Zenke   +5 more
openaire   +2 more sources

Heparin-Conjugated Polyethylenimine for Gene Delivery

Journal of Controlled Release, 2008
A major problem when using cationic polymers for gene delivery is that transfection is strongly inhibited by the presence of serum. This shortcoming limits the application of cationic polymers for systematic gene delivery in vivo. Due to the shielding effect of heparin, heparin conjugation to cationic polymers may improve the in vivo gene transfection ...
Byung-Soo Kim, Tae-Jin Lee, Oju Jeon
exaly   +3 more sources

Surface chemical analysis and chromatographic characterization of polyethylenimine-coated hydroxyapatite with various amount of polyethylenimine

Talanta, 2011
Polyethylenimine (PEI) has been widely used as a coating material to produce stationary phase for ion-exchange chromatography of biomolecules. However, a precise study of the PEI coating fraction has been lacking, despite such quantification being very important for fundamental research as well as identifying further industrial applications.
Yukiko, Murakami, Ken, Sugo, Masahiro, Hirano, Tsuneo, Okuyama   +3 more
openaire   +2 more sources

Extracorporeal Endotoxin Removal by Immobilized Polyethylenimine

Artificial Organs, 1993
Abstract: The neutralization of bacterial endotoxins (ET) is still an unsolved problem in therapeutic medicine. The efficacy of antiendotoxin antibodies or receptor antagonists and other substances interferring with the endotoxininduced pathomechanisms is dependent on an intact cellular degradation system of the host.
S, Mitzner, J, Schneidewind, D, Falkenhagen, F, Loth, H, Klinkmann   +4 more
openaire   +2 more sources

Chitosan-graft-polyethylenimine as a gene carrier

Journal of Controlled Release, 2007
Chitosans have been proposed as biocompatible alternative cationic polymers that are suitable for non-viral delivery. However, the transfection efficiency of chitosan-DNA nanoparticles is still very low. To improve transfection efficiency, we prepared chitosan-graft-polyethylenimine (CHI-g-PEI) copolymer by an imine reaction between periodate-oxidized ...
Hu-Lin, Jiang, You-Kyoung, Kim, Rohidas, Arote, Jae-Woon, Nah, Myung-Haing, Cho, Yun-Jaie, Choi, Toshihiro, Akaike, Chong-Su, Cho   +7 more
openaire   +2 more sources

Gene transfer with modified polyethylenimines

The Journal of Gene Medicine, 2004
Branched and linear polyethylenimines (PEIs) have proven to be efficient and versatile agents for gene delivery in vitro. In addition, systemic administration of positively charged DNA/PEI complexes results in significant reporter gene expression in lungs.
openaire   +2 more sources

Synthesis of Linear Polyethylenimine and Use in Transfection

Cold Spring Harbor Protocols, 2012
Linear polyethylenimine (LPEI) is an efficient transfection reagent for a broad range of cell lines and primary cells and is also useful for local or systemic gene delivery in vivo. In contrast to many other nonviral transfection methods, LPEI is less dependent on mitosis and also transfects postmitotic cells.
Manfred, Ogris, Ernst, Wagner
openaire   +2 more sources

Polyethylenimine-based Formulations for Delivery of Oligonucleotides

Current Medicinal Chemistry, 2019
Polyethyleneimine (PEI) is well-known as a non-viral gene delivery vector, especially for oligonucleotide delivery. However, its clinical applications are significantly limited due to its high cationic charge, lack of specificity, and interaction with the proteins and nontarget cells in the biological fluids, resulting in high cytotoxicity, poor ...
Fei, Hao, Yuhuan, Li, Jing, Zhu, Jingyao, Sun, Brian, Marshall, Robert J, Lee, Lesheng, Teng, Zhaogang, Yang, Jing, Xie   +8 more
openaire   +2 more sources

Cooperativity and Selectivity in Chemomechanical Polyethylenimine Gels

Langmuir, 2007
Gel particles obtained from polyethylenimine (PEI) cross-linked with 10% ethylene glycol diglycidyl ether show considerable selectivity in size changes if exposed to solutions of different effector compounds. Monocarboxylic acids induce contractions of, e.g., -9% for benzoate and -40% for 2-naphthoate (all values in one dimension such as length).
Kazuaki, Kato, Hans-Jörg, Schneider
openaire   +2 more sources