Results 101 to 110 of about 1,875 (207)

β-Nitro acrylic esters as precursors for the one pot synthesis of polyfunctionalized α,β-unsaturated esters

, 2005
Conjugate addition of activated methylene derivatives to β-nitro acrylic esters in acetonitrile with DBU (2 equiv) as base, allows the one pot formation of polyfunctionalized α,β-unsaturated esters.
Alessandro Palmieri, Dennis Fiorini, Roberto Ballini, BALLINI, Roberto, FIORINI, Dennis, PALMIERI, Alessandro   +5 more
core   +1 more source

Base-Promoted Denitrogenative/Deoxygenative/Deformylative Benzannulation of N‑Tosylhydrazones with 3‑Formylchromones for Diverse and Polyfunctionalized Xanthones

, 2018
A simple and efficient base-promoted denitrogenative/deoxygenative/deformylative benzannulation is developed for the construction of biologically interesting polyfunctionalized xanthones starting from N-tosylhydrazones and two molecules of 3 ...
Yong Rok Lee (1608961), Rajeev Shrestha, Rajeev Shrestha (5901815), Yong Rok Lee   +3 more
core   +1 more source

Application of the nitroaldol (Henry) reaction for a two-step sequence in the synthesis of polyfunctionalized dihydropyran derivatives

, 2007
Nitroaldol (Henry) reaction of a variety of nitroalkanes, under neat t-BuOK catalysis, allows a one-pot synthesis of polyfunctionalized tetrahydropyranols which, with CeCl3-7H(2)O/NaI system, dehydrate to dihydropyran derivatives. Thus, the dibydropyrans
GABRIELLI, Serena, BALLINI, Roberto, PALMIERI, Alessandro   +2 more
core   +1 more source

An overview of synthesis and biological activities of 2-pyridone derivatives over the last decade

Discover Applied Sciences
2-Pyridone frameworks are a pervasive member of the N-heterocyclic family of both chemical and therapeutic interest. 2-Pyridones and their bridged analogues have wide occurrences in nature and the presence of both aromatic and amide groups in the ...
Lopamudra Das, Tista Sengupta
doaj   +1 more source

Solid-state synthesis of polyfunctionalized 2-pyridones and conjugated dienes

Functionalized 2-pyridones are important biologically active compounds, DNA base analogues and synthetic intermediates. Herein, we report a simple, green, solid-state synthesis of differently substituted 2-pyridones. It starts from commercially available
Aleksić, Jovana, Stojanović, Milovan, Stanisavljević, Anđela, Baranac-Stojanović, Marija   +3 more
core   +1 more source

Generation and validation of a novel multitarget small molecule in glioblastoma

Cell Death and Disease
The development of multitarget small molecules (MSMs) has emerged as a powerful strategy for the treatment of multifactorial diseases such as cancer. Glioblastoma is the most prevalent and malignant primary brain tumor in adults, which is characterized ...
Aizpea Artetxe-Zurutuza, Nerea Iturrioz-Rodriguez, Joseba Elizazu, Mireia Toledano-Pinedo, Alicia Porro-Pérez, Irati De Goñi, Alejandro Elua-Pinin, Linda Schäker-Hübner, Mikel Azkargorta, Felix Elortza, Isabel Iriepa, Francisco Lòpez-Muñoz, Veronica Moncho-Amor, Finn K. Hansen, Nicolás Sampron, Jose Luis Marco-Contelles, Ander Matheu   +16 more
doaj   +1 more source

Unusual ring transformation of N-hydroxy-3,5-dinitro-4-pyridone Affording a polyfunctionalized pyrrole

Polyfunctionalized pyrrole 6 is synthesized in the ring transformation of N-hydroxy-3,5-dinitro4-pyridone 4 with enolate 2 derived from diethyl 3-oxogulutarate. The present reaction proceeds with C-N transfer from 4 to 2, which is hitherto unknown manner
ホリ, カズシゲ, アサカ, ノリコ, MATSUSHIMA, Kazuo, 安積, 典子, 堀, 一繁, TOHDA, Yasuo, マツシマ, カズオ, HORI, Kazushige, ニシワキ, ナガトシ, ASAKA, Noriko, トウダ, ヤスオ, 有賀, 正裕, 任田, 康夫, 西脇, 永敏, NISHIWAKI, Nagatoshi, タムラ, ミナ, 田村, 美奈, アリガ, マサヒロ, TAMURA, Mina, ARIGA, Masahiro   +19 more
core  

Ylidic polyfunctionalized compounds with a diazinium skeleton

ARKIVOC, 2002
Maria C. Caprosu, Mioara A. Andrei, Geanina C. Mangalagiu, Magda Ghe. Petrovanu, Ionel I. Mangalagiu   +4 more
doaj   +1 more source

Acridine yellow G (AYG) as a photo-induced electron transfer (PET) photocatalyst employed for the radical Michael-Mannich cyclocondensation of imines. [PDF]

Front Chem, 2022
Mohamadpour F.
europepmc   +1 more source

Creating unimolecular multivalent diversity in protein conjugates via the Passerini multicomponent bioconjugation with isocyanoproteins. [PDF]

Commun Chem
Humpierre AR, Méndez Y, Kim A, Niemeyer M, Frolov A, Saenz M, Garrido R, Reguera L, Santana-Mederos D, Garcia-Rivera D, Westermann B, Rivera DG.   +11 more
europepmc   +1 more source