Results 171 to 180 of about 4,131 (247)

Electroreductive synthesis of polyfunctionalized pyridin-2-ones from acetoacetanilides and carbon disulfide with oxygen evolution.

Organic and biomolecular chemistry, 2022
A chemical reductant or a sacrificial electron donor is required in any reduction reactions, generally resulting in undesired chemical waste. Herein, we report a reductant-free reductive [3 + 2 + 1] annulation of β-keto amides with CS2 enabled by the ...
Lichun Xu, Zhongxiao Ma, Xi Hu, Xin Zhang, Shulin Gao, Deqiang Liang, Baoling Wang, Weili Li, Yanni Li   +8 more
semanticscholar   +1 more source

One-Step Polyfunctionalization of (Methylthio)thiophenes

Synthesis, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
FATTUONI, CLAUDIA, Usai Michele, Cabiddu Maria G., CADONI, ENZO, De Montis Stefania, CABIDDU, MARIA GRAZIA   +5 more
openaire   +1 more source

Synthesis of polyfunctionalized acylsilanes via propenoyltrimethylsilane.

Tetrahedron Letters, 1987
Abstract Propenoyltrimethylsilane (1) reacts with silylated nucleophiles to yield the β-functionalised silyl enol ethers of acylsilanes. Further “in situ” reaction of these compounds affords an easy entry into the class of polyfunctionalised acylsilanes.
Ricci Alfredo, Degl'Innocenti Alessandro, Borselli Giovanna, Reginato Gianna   +3 more
openaire   +3 more sources

Synthesis of Polyfunctionalized Hexahydropyrimidines

Russian Journal of Organic Chemistry, 2019
The reactions of alkyl 5-acetylhexahydropyrimidine-5-carboxylates with ammonia, hydrazine hydrate, and lithium aluminum hydride were used to synthesize hexahydropyrimidine derivatives containing pharmacophoric 1,3-propylenediamine and 1,3-propanolamine fragments.
A. G. Badamshin, D. R. Latypova, V. A. Dokichev   +2 more
openaire   +1 more source

Crown Macromolecular Derivatives: Stepwise Design of New Types of Polyfunctionalized Phosphorus Dendrimers.

Journal of Organic Chemistry, 2022
Phosphorus dendrimers are used for many applications in different domains including nanomedicine as cargo of drugs or as species active per se but also in a variety of other fields ranging from nanoscience to catalysis.
A. Karpus, S. Mignani, M. Zabłocka, J. Majoral   +3 more
semanticscholar   +1 more source

Multicomponent synthesis, in vitro cytotoxic evaluation and molecular modelling studies of polyfunctionalized pyrazolo[3,4-b]pyridine derivatives against three human cancer cell lines

Synthetic Communications, 2021
A series of diversely polyfunctionalized pyrazolo[3,4-b]pyridines were synthesized by the multicomponent reaction of phenyl/benzothiazolylhydrazine and 3-oxo-3-arylpropanenitrile with 1,3-diketones under solvent-free and solvent-mediated conditions ...
R. Aggarwal, Suresh Kumar, Rachna Sadana, A. Guzmán, Virender Kumar   +4 more
semanticscholar   +1 more source

Polyfunctionally Pyrazole Azo Dyes

Pigment & Resin Technology, 1994
In recent years heterocyclic azo dyes have been the subject of an intense research by dye manufacturers. Even so, little has been devoted to technical properties, so we have recently directed our research activities towards studying the ability of thiazole azo and hydrazono disperse dyes for dyeing of polyester and cellulose acetate.
Y.M. ElKholy, S.A. Abd El‐Hafiz
openaire   +1 more source

Simple Units Integration Brings New Reactivity: Neighboring Group Effect in the Synthesis of Polyfunctionalized 5‐Alkenyl‐3‐furanones from γ‐Hydroxyl Enal

Chinese journal of chemistry
With the hypothesis of simple units integration to create new reactivities, a strategy for the synthesis of polyfunctionalized 5‐alkenyl‐3‐carbonylfurans from γ‐hydroxyl enal and 1,3‐dicarbonyl compounds is established, featuring readily available ...
Jun Tan, Chengyan Xie, Youai Qiu, Dengke Ma   +3 more
semanticscholar   +1 more source

Unanticipated Three-Component Cascade and Sequential Cyclization: Highly Diastereoselective Synthesis of Polyfunctionalized Cyclohexanes.

Journal of Organic Chemistry
Herein, we reported a DBU-catalyzed cascade and sequential [1 + 2 + 3] annulation of malononitrile with α,β-unsaturated ketones to access polyfunctionalized cyclohexanes with high yield and excellent diastereoselectivity (>93% yield, >19:1 dr ...
Qing He, Rui Zhou, Bin Liu, Rong-Hua Wang, Xiangkai Kong, Siyu He, Jianta Wang, Lingling Fan, Xiaozhong Fu, Lei Tang   +9 more
semanticscholar   +1 more source

Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases.

Journal of Medicinal Chemistry
Herein, we describe the design, synthesis, and biological evaluation of 15 Contilisant+Tubastatin A hybrids. These ligands are polyfunctionalized indole derivatives developed by juxtaposing selected pharmacophoric moieties of Contilisant and Tubastatin A
Mireia Toledano-Pinedo, Alicia Porro-Pérez, Linda Schäker-Hübner, F. Romero, M. Dong, A. Samadi, P. Almendros, I. Iriepa, Óscar M. Bautista-Aguilera, M. M. Rodríguez-Fernández, Cristina Solana-Manrique, Inmaculada Sanchis, Alba Mora-Morell, Ania Canseco Rodrìguez, A. Sánchez-Pérez, D. Knez, Stanislav Gobec, A. Bellver-Sanchis, Belén Pérez, A. Dobrydnev, Aizpea Artetxe-Zurutuza, A. Matheu, A. Siwek, Małgorzata Wolak, G. Satała, A. Bojarski, Agata Doroz‐Płonka, J. Handzlik, Justyna Godyń, Anna Więckowska, N. Paricio, C. Griñán-Ferré, Finn K. Hansen, José Marco-Contelles   +33 more
semanticscholar   +1 more source