Results 31 to 40 of about 4,131 (247)
Straightforward Access to Polyfunctionalized δ-Lactams via Domino Aza–Michael/Thia–Michael/Aldol Sequence [PDF]
MoleculesDomino reactions are powerful tools for the straightforward synthesis of complex molecules with a particular emphasis on functionalized azacycles. We report a contribution in this field, implemented via a new thia–Michael/aldol sequence between readily ...
Axelle Genty +6 more
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(Z)-2-{[(4-Chloro-5H-1,2,3-dithiazol-5-ylidene)amino](methylthio)methylene}malononitrile
Molbank, 2022 Reaction of 4,5-dichloro-1,2,3-dithiazolium chloride with 2-[amino(methylthio)methylene])malononitrile (1 equiv) in the presence of pyridine (2 equiv) gave (Z)-2-{[(4-chloro-5H-1,2,3-dithiazol-5-ylidene)amino](methylthio)methylene}malononitrile in 20 ...
Andreas S. Kalogirou +1 more
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(E)-4-Oxo-3,4-dihydroquinazoline-2-carbaldehyde Oxime
Molbank, 2021 Reaction of 4-oxo-3,4-dihydroquinazoline-2-carbaldehyde with hydroxylamine hydrochloride (1.1 equiv) in the presence of K2CO3 (1 equiv) gave (E)-4-oxo-3,4-dihydroquinazoline-2-carbaldehyde oxime (8) in 58% yield.
Andreas S. Kalogirou +2 more
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Reactions of 4H-1,2,6-Thiadiazine Sulfides
Molbank, 2022 3,5-Dichloro-4H-1,2,6-thiadiazin-4-one reacts with benzo[d]thiazole-2-thiol (1 equiv) and triethylamine (1 equiv) to give 3-(benzo[d]thiazol-2-ylthio)-5-chloro-4H-1,2,6-thiadiazin-4-one in 71% yield.
Andreas S. Kalogirou +1 more
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Reaction of 4,5-Dichloro-1,2,3-dithiazolium Chloride with 2-(Phenylsulfonyl)acetonitrile
Molbank, 2022 The reaction of 4,5-dichloro-1,2,3-dithiazolium chloride with 2-(phenylsulfonyl)acetonitrile (1 equiv) in the presence of pyridine (2 equiv) gave S-(3-chloro-5-cyanoisothiazol-4-yl)benzenesulfonothioate and (Z)-2-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)-2-
Konstantinos Plakas +3 more
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2-Amino-5-chloro-1H-pyrrole-3,4-dicarbonitrile
Molbank, 2021 The reaction of tetracyanoethylene (TCNE) with HCl (g) in the presence of Sn (1 equiv) and AcOH resulted in 2-amino-5-chloro-1H-pyrrole-3,4-dicarbonitrile in a 74% yield. The compound was fully characterized.
Andreas S. Kalogirou +1 more
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Methyl 3-Bromo-5-carbamoylisothiazole-4-carboxylate
Molbank, 2023 Reaction of methyl 3-bromo-5-cyanoisothiazole-4-carboxylate with conc. H2SO4 gave methyl 3-bromo-5-carbamoylisothiazole-4-carboxylate in 93% yield. The compound was fully characterized.
Andreas S. Kalogirou +1 more
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Molecules, 2022 A solvent-free two-step synthesis of polyfunctionalized pyrazoles under ball-milling mechanochemical conditions was developed. The protocol comprises (3 + 2)-cycloaddition of in situ generated nitrile imines and chalcones, followed by oxidation of the ...
Greta Utecht-Jarzyńska +2 more
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Current Chemistry Letters, 2023 This work includes the synthesis of ten heterocyclic compounds (3a-i and 4) containing pyrimidine moiety incorporated in their structures. Structure characterizations of these compounds were performed by using elemental and spectroscopic analyses.
A. M. Drar +3 more
semanticscholar +1 more source
Synthesis and cyclization reactions of 2-(6-methylquinolin-4-yl)malononitriles and ethyl 2-cyano-2-(6-methylquinolin-4-yl)acetates [PDF]
Journal of the Serbian Chemical Society, 2006 The nucleophilic substitution reactions of 2,4-dichloro-6-methylquinoline (1) and 4-chloro-6-methylquinolin-2(1H)-one (7) with malononitrile and ethyl cyanoacetate are described. The quinolinylmalononitrile 8a and cyanoacetate 8b were utilized to prepare
MOSTAFA M. ISMAIL
doaj +3 more sources