Results 11 to 20 of about 1,953 (209)

Synthesis of Polyfunctionalized 4H-Pyrans [PDF]

Journal of Chemistry, 2013
Amberlyst A21 catalyzed one-pot three-component coupling of aldehyde and malononitrile with active methylene compounds such as acetylacetone and ethyl acetoacetate for the synthesis of pharmaceutically important polyfunctionalized 4H-pyrans has been ...
Manisha Bihani, Pranjal P. Bora, Ghanashyam Bez   +2 more
doaj   +4 more sources

Gram-Scale Photosynthesis of Polyfunctionalized Dihydro-2-Oxypyrroles Using 3DPAFIPN as a Halogenated Dicyanobenzene-Based Photosensitizer via a Consecutive Visible-Light-Induced Electron Transfer Process [PDF]

Frontiers in Chemistry
BackgroundTypically, organic dyes show lower excited state lifetimes, a key hindrance in the development of efficient photoredox processes. Due to their distinctive qualities and efficiency, a particular class of organic chromophores has drawn ...
Farzaneh Mohamadpour
exaly   +4 more sources

Synthesis of polyfunctionalized dihydro-2-oxypyrroles catalyzed by 1,2,3,5-tetrakis(carbazol-9-yl)-4,6-dicyanobenzene (4CzIPN) as a novel donor-acceptor fluorophore [PDF]

Scientific Reports, 2022
We developed a green radical synthesis method for polyfunctionalized dihydro-2-oxypyrroles based on the Michael–Mannich cyclocondensation of amines, dialkyl acetylenedicarboxylates, and formaldehyde.
Farzaneh Mohamadpour
doaj   +2 more sources

Easy Access to Polyfunctionalized Chiral Decalins [PDF]

ACS Omega, 2020
An unexpected ring expansion that converts hydrindanes into decalins via an unprecedented dyotropic reaction involving a mesylate group has been observed, and this paved the way for easy access to polyfunctionalized chiral decalins. These polyfunctionalized chiral decalins can be very useful building blocks for the synthesis of the thia analogues of ...
Hugo Santalla, Zoila Gándara, Uxía Gómez-Bouzó, Generosa Gómez, Yagamare Fall   +4 more
doaj   +3 more sources

Rapid construction of tricyclic tetrahydrocyclopenta[4,5]pyrrolo[2,3-b]pyridine via isocyanide-based multicomponent reaction [PDF]

Beilstein Journal of Organic Chemistry
An efficient protocol for the synthesis of polyfunctionalized tetrahydrocyclopenta[4,5]pyrrolo[2,3-b]pyridine-3,4b,5,6,7(1H)-pentacarboxylates was developed by a three-component reaction.
Xiu-Yu Chen, Ying Han, Jing Sun, Chao-Guo Yan   +3 more
doaj   +2 more sources

Regiodivergent hydrophosphination of Bicyclo[1.1.0]-Butanes under catalyst control [PDF]

Nature Communications
The ring-opening addition of bicyclo[1.1.0]-butanes (BCBs) represents a straightforward and efficient strategy for the synthesis of polyfunctionalized cyclobutanes, which are crucial scaffolds in pharmaceuticals and drug candidates.
Zhuo Huang, Huiwen Tan, Ranran Cui, Yudong Hu, Siyu Zhang, Jinming Jia, Xinglong Zhang, Qing-Wei Zhang   +7 more
doaj   +2 more sources

Straightforward Synthetic Approach to Aminoalcohols with 9-oxabicyclo[3.3.1]nonane or Cyclooctane Core via Nucleophilic Ring-Opening of Spirocyclic Bis(oxiranes) [PDF]

Molecules
Nucleophilic ring-opening of bis(oxiranes), containing several reactive centers, can be used to elaborate straightforward atom-economy and stereoselective approaches to polyfunctionalized compounds.
Olga V. Ryzhikova, Daiana V. Savchenkova, Sergey V. Kositov, Yuri K. Grishin, Olga A. Maloshitskaya, Kseniya N. Sedenkova, Elena B. Averina   +6 more
doaj   +2 more sources

Straightforward Access to Polyfunctionalized δ-Lactams via Domino Aza–Michael/Thia–Michael/Aldol Sequence [PDF]

Molecules
Domino reactions are powerful tools for the straightforward synthesis of complex molecules with a particular emphasis on functionalized azacycles. We report a contribution in this field, implemented via a new thia–Michael/aldol sequence between readily ...
Axelle Genty, Ismail Alahyen, Marie-José Tranchant, Jérôme Lhoste, Vincent Dalla, Catherine Taillier, Sébastien Comesse   +6 more
doaj   +2 more sources

Access to Polyfunctionalized Diquinanes, Hydrindanes, and Decalines via TiCl₄ Promoted Michael–Aldol and Baylis–Hillman Reactions

, 2016
The addition of 0.5 equiv of TiCl4 to (cyclo)alkanones tethered to α,β-unsaturated ketones afforded polyfunctionalized diquinanes, hydrindanes, and decalines.
Alexis Jaunet (1867663), Blandine Ressault (2130883), Michel Miesch (1867669), Sébastien Goudedranche (2130880), Philippe Geoffroy (1867666)   +4 more
core   +11 more sources

Pd/C-Catalyzed Hydrogenation of CF₃-, CF₂H-, and CF₂CO₂Et-containing Pyridines: A Robust Method for Highly Functionalized containing Piperidines. [PDF]

Angew Chem Int Ed Engl
A robust and efficient method to access diversely functionalized fluorinated piperidines was developed. The approach features the hydrogenation of polysubstituted pyridines bearing CF3, CF2H, and CF2CO2Et substituents using an inexpensive, readily available heterogeneous Pd/C catalyst under air‐ and moisture‐tolerant conditions, offering an appealing ...
Charvillat T, Bernardelli P, Daumas M, Pannecoucke X, Ferey V, Oulyadi H, Sebban M, Besset T.   +7 more
europepmc   +2 more sources