Results 21 to 30 of about 672 (165)
2-Amino-5-chloro-1H-pyrrole-3,4-dicarbonitrile
Molbank, 2021 The reaction of tetracyanoethylene (TCNE) with HCl (g) in the presence of Sn (1 equiv) and AcOH resulted in 2-amino-5-chloro-1H-pyrrole-3,4-dicarbonitrile in a 74% yield. The compound was fully characterized.
Andreas S. Kalogirou +1 more
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Methyl 3-Bromo-5-carbamoylisothiazole-4-carboxylate
Molbank, 2023 Reaction of methyl 3-bromo-5-cyanoisothiazole-4-carboxylate with conc. H2SO4 gave methyl 3-bromo-5-carbamoylisothiazole-4-carboxylate in 93% yield. The compound was fully characterized.
Andreas S. Kalogirou +1 more
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Molecules, 2022 A solvent-free two-step synthesis of polyfunctionalized pyrazoles under ball-milling mechanochemical conditions was developed. The protocol comprises (3 + 2)-cycloaddition of in situ generated nitrile imines and chalcones, followed by oxidation of the ...
Greta Utecht-Jarzyńska +2 more
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Synthesis and cyclization reactions of 2-(6-methylquinolin-4-yl)malononitriles and ethyl 2-cyano-2-(6-methylquinolin-4-yl)acetates [PDF]
Journal of the Serbian Chemical Society, 2006 The nucleophilic substitution reactions of 2,4-dichloro-6-methylquinoline (1) and 4-chloro-6-methylquinolin-2(1H)-one (7) with malononitrile and ethyl cyanoacetate are described. The quinolinylmalononitrile 8a and cyanoacetate 8b were utilized to prepare
MOSTAFA M. ISMAIL
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Evaluating Cellular Polyfunctionality with a Novel Polyfunctionality Index
PLoS ONE, 2012 Functional evaluation of naturally occurring or vaccination-induced T cell responses in mice, men and monkeys has in recent years advanced from single-parameter (e.g. IFN-γ-secretion) to much more complex multidimensional measurements. Co-secretion of multiple functional molecules (such as cytokines and chemokines) at the single-cell level is now ...
Larsen, Martin +5 more
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Molecules, 2023 Sequential reactions of aminoalkynes represent a powerful tool to easily assembly biologically important polyfunctionalized nitrogen heterocyclic scaffolds.
Antonio Arcadi +2 more
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Antioxidants, 2022 Nowadays, most stroke patients are treated exclusively with recombinant tissue plasminogen activator, a drug with serious side effects and limited therapeutic window. For this reason, and because of the known effects of oxidative stress on stroke, a more
Daniel Diez-Iriepa +8 more
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E-Journal of Chemistry, 2012 Polyfunctionalized amino furans with long conjugated aromatic systems have been synthesized by three component reaction of aldehydes, acetylenic esters and aromatic nucleophilic isocyanide.
Mohammad Qandalee +3 more
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Affix polyfunctionality in French deverbal nominalizations
Morphology, 2022 AbstractThis article investigates the semantic polyfunctionality of affixes, i.e. their ability to serve a variety of distinct semantic functions. Based on the analysis of a sample of 3,091 deverbal nouns ending with 46 different suffixes in French, the study examines the diversity of semantic functions realized by deverbal suffixes, the distribution ...
Justine Salvadori, Richard Huyghe
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Glutamic acid as green and bio-based α-amino acid catalyst promoted one-pot access to polyfunctionalized dihydro-2-oxypyrroles [PDF]
Journal of the Serbian Chemical Society, 2019 A highly versatile and convenient synthetic route for biologically active α-amino acid, glutamic acid catalyzed facile and mild preparation of polyfunctionalized dihydro-2-oxypyrroles via one-pot, four condensation domino reaction between aromatic ...
Mohamadpour Farzaneh
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