Results 21 to 30 of about 1,650,847 (244)
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Background Myocardial infarction (MI) is a significant clinical and public health problem worldwide. However, little research has assessed the interplay between genetic susceptibility and social environment in the development of MI.
Junhan Tang +4 more
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, 2022 Additional file 3: Polygenic risk score methodology and reclassification ...
Lang Wu (540806) +4 more
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, 2023 Thyroid cancer molecular subtypes and polygenic ...
Jennifer Wang (16385040)
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Polygenic risk score improves the accuracy of a clinical risk score for coronary artery disease
BMC Medicine, 2022 Background The value of polygenic risk scores (PRSs) towards improving guideline-recommended clinical risk models for coronary artery disease (CAD) prediction is controversial.
Austin King +4 more
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Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores
Nature Communications, 2021 While polygenic risk scores have been shown to be correlated with disease risk, there is little agreement on how the score should be calculated. Here the authors investigate risk scores for Alzheimer’s disease, finding that the most effective approach ...
Ganna Leonenko +7 more
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Association between a polygenic risk score (PRS) and type 2 diabetes at baseline.
, 2023 Association between a polygenic risk score (PRS) and type 2 diabetes at baseline.
Dale S. Hardy (3708508) +2 more
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Education and prosocial behaviours: a polygenic score approach
, 2023 Secondary data analysis based on survey data from LASA and a polygenic score for educational attainment constructed from GWAS summary statistics.
Eva-Maria Merz +3 more
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Can education be personalised using pupils’ genetic data?
eLife, 2020 The increasing predictive power of polygenic scores for education has led to their promotion by some as a potential tool for genetically informed policy. How accurately polygenic scores predict an individual pupil's educational performance conditional on
Tim T Morris +2 more
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Multi-polygenic score approach to trait prediction [PDF]
, 2017 A primary goal of polygenic scores, which aggregate the effects of thousands of trait-associated DNA variants discovered in genome-wide association studies (GWASs), is to estimate individual-specific genetic propensities and predict outcomes.
S Newhouse +36 more
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