Results 151 to 160 of about 16,136 (210)

Spinocerebellar Ataxia Type 1 (SCA1) Cell Models Display Widespread Mitochondrial and Extra-Nuclear Alterations. [PDF]

J Mol Neurosci
Ford-Roshon D, Dudek M, Glynn A, Glasman A, York J, Lawrence E, Nguyen D, Shinn L, Berry G, Kendall L, Bonner J, Ferro A, Lagalwar S.   +12 more
europepmc   +1 more source

Polyglutamine expansion induced dynamic misfolding of androgen receptor. [PDF]

Protein Sci
Heling LWHJ, Sheikhhassani V, Ng J, van Vliet M, Jiménez-Panizo A, Alegre-Martí A, Woodard J, van Roon-Mom W, McEwan IJ, Estébanez-Perpiñá E, Mashaghi A.   +10 more
europepmc   +1 more source

Unbiased human genomic characterization of polyglutamine disorder genes to guide biological understanding and therapeutic strategies. [PDF]

HGG Adv
Namuli KL, Drögemöller BI, Wright GEB.
europepmc   +1 more source

Levels of supramolecular chirality of polyglutamine aggregates revealed by vibrational circular dichroism

, 2013
Dmitry Kurouski, Karunakar Kar, Ronald Wetzel, Rina K. Dukor, Igor K. Lednev, Laurence A. Nafié   +5 more
openalex   +1 more source

PROTACs therapeutically target the polyglutamine androgen receptor in spinal and bulbar muscular atrophy models. [PDF]

Neurotherapeutics
Sangotra A, Reddy SL, Kuo CJ, Xiang W, Merry DE, Grunseich C, Wang S, Lieberman AP.   +7 more
europepmc   +1 more source

Molecular hallmarks of neurodegeneration in polyglutamine spinocerebellar ataxias. [PDF]

Cell Death Dis
Nóbrega C, Marcelo A, Rajado AT, Conceição A, Estevam B, Matos CA, Brito DV, Afonso IT, Codêsso JM, Koppenol R, Costa RG, Afonso-Reis R, Paulino R, Moreira-Gomes T.   +13 more
europepmc   +1 more source

Structure of polyglutamine

FEBS Letters, 2000
Altschuler, Eric Lewin, Hud, Nicholas V., Mazrimas, Joseph A., Rupp, Bernhard   +3 more
openaire   +1 more source

A Coarse-Grained MD Model for Disorder-To-Order Transitions in PolyQ Aggregation. [PDF]

J Chem Theory Comput
Dekker M, van der Klok ML, Van der Giessen E, Onck PR.   +3 more
europepmc   +1 more source

Calpains in the Molecular Pathogenesis of Polyglutamine Disorders and Their Potential as a Therapeutic Target

, 2018
Jonasz Jeremiasz Weber
openalex   +1 more source

Biologic Significance of the Short Tandem Trinucleotide Repeats in the Androgen Receptor Gene.

J Clin Endocrinol Metab
Bhasin S.
europepmc   +1 more source