Results 131 to 140 of about 30,328 (180)

Role of the chaperonin TCP-1 ring complex in protein aggregation and neurodegeneration. [PDF]

Front Mol Neurosci
Varte V, Rincon-Limas DE.
europepmc   +1 more source

Pediatric-onset spinocerebellar ataxia type 3 with dual <i>ATXN3</i> and <i>HTT</i> gene mutations: a case report and literature-informed hypothesis. [PDF]

Front Genet
Wang D, Zhou M, Du K, Wang Y, Tang K, Duan Y, Shi M, Wu H.   +7 more
europepmc   +1 more source

Analysis of short tandem repeats linked to polyglutamine diseases from whole-genome sequencing reveals intermediate alleles of <i>HTT</i> associated with an early disease onset in <i>C9orf72</i> carriers. [PDF]

Brain Commun
Barbier M, Gareau T, Camuzat A, Guillaud-Bataille M, Boluda S, Clot F, Araktingi L, Borroni B, van der Zee J, Ghidoni R, Bellini S, Galimberti D, Rossi G, Nacmias B, De la Casa-Fages B, Pastor P, French Clinical and Genetic Research Network on FTD/FTD-ALS and PrevDemALS Study Groups , Latouche M, le Guern E, Durr A, Laquerrière A, Moccia R, Seilhean D, Alvarez V, Le Ber I.   +24 more
europepmc   +1 more source

An acyclic nucleic acid-modified siRNA targeting CAG expansions for polyglutamine disease treatment. [PDF]

Mol Ther Nucleic Acids
Maeda K, Hirunagi T, Sahashi K, Kamiya Y, Iida M, Sakakibara K, Onodera K, Ohyama M, Okada Y, Okano H, Asanuma H, Katsuno M.   +11 more
europepmc   +1 more source

Aggregate fragmentation: the ticket to aggrephagy. [PDF]

Autophagy
Mauthe M, Kampinga H, Reggiori F.
europepmc   +1 more source

Electrical silencing of dendritic arborization neurons rescues toxic polyglutamine-induced locomotion defect. [PDF]

Fly (Austin)
Miao H, Kim WJ.
europepmc   +1 more source

Identification of Splicing Regulatory Activity of ATXN1 and Its Associated Domains. [PDF]

Biomolecules
Ohki A, Kato M, Aoki Y, Kubokawa A, Yanaizu M, Kino Y.   +5 more
europepmc   +1 more source

Epitope-specific antibodies can distinguish between soluble huntingtin exon-1 and its diverse cellular aggregates. [PDF]

J Biol Chem
Lugo J, Xu H, Chen J, Khoshnan A, Langen R.   +4 more
europepmc   +1 more source

Familial spinocerebellar ataxia type 3: A case report of multi-generational presentation. [PDF]

Medicine (Baltimore)
Wang J, Liu Z, Shi C, Pan C, Chen J, Zhao Z, Yang D, Huang H.   +7 more
europepmc   +1 more source

Multiscale Simulations Elucidate the Mechanism of Polyglutamine Aggregation and the Role of Flanking Domains in Fibril Polymorphism. [PDF]

J Phys Chem B
Kulshrestha A, Phan TM, Rizuan A, Mohanty P, Mittal J.   +4 more
europepmc   +1 more source