Results 171 to 180 of about 30,328 (180)

A novel therapeutic strategy for polyglutamine diseases by stabilizing aggregation-prone proteins with small molecules

Journal of Molecular Medicine, 2005
Motomasa Tanaka, Nobuyuki Nukina
exaly  

Huntingtin toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1

Journal of Cell Biology, 2002
Anatoli B Meriin, Xiangwei He, Yury O Chernoff   +2 more
exaly  

Solubilization and disaggregation of polyglutamine peptides

Protein Science, 2001
Ronald Wetzel
exaly  

PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins

Journal of Cell Biology, 2006
Elodie Martin, Alexis Brice, Yvon Trottier   +2 more
exaly  

Random coil conformation for extended polyglutamine stretches in aqueous soluble monomeric peptides

Chemical Biology and Drug Design, 1997
Nicholas V Hud, Bernhard Rupp
exaly  

Transformation between α‐helix and β‐sheet structures of one and two polyglutamine peptides in explicit water molecules by replica‐exchange molecular dynamics simulations

Journal of Computational Chemistry, 2014
Chun-Jung Chen, Hisashi Okumura, Chin-Kun Hu   +2 more
exaly  

Effects of chain length on the aggregation of model polyglutamine peptides: Molecular dynamics simulations

Proteins: Structure, Function and Bioinformatics, 2007
Carol K Hall
exaly  

Recent advances in understanding the pathogenesis of polyglutamine diseases: involvement of molecular chaperones and ubiquitin-proteasome pathway

Journal of Chemical Neuroanatomy, 2003
Nihar Ranjan Jana, Nobuyuki Nukina
exaly  

Extended polyglutamine selectively interacts with caspase-8 and -10 in nuclear aggregates

Cell Death and Differentiation, 2001
exaly  

Protective effect of chaperones on polyglutamine diseases

Brain Research Bulletin, 2001
Sobue
exaly