Results 91 to 100 of about 11,293 (160)

Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation? [PDF]

Cell Death Dis, 2021
Marcelo A, Koppenol R, de Almeida LP, Matos CA, Nóbrega C.   +4 more
europepmc   +1 more source

Extracellular Vesicles Physiological Role and the Particular Case of Disease-Spreading Mechanisms in Polyglutamine Diseases. [PDF]

Int J Mol Sci, 2021
Moreira R, Mendonça LS, Pereira de Almeida L.   +2 more
europepmc   +1 more source

Developmental Alterations in Adult-Onset Neurodegenerative Disorders: Lessons from Polyglutamine Diseases. [PDF]

Mov Disord, 2021
Edamakanti CR, Opal P.
europepmc   +1 more source

Discovery of a mutation-containing circRNA in polyglutamine disease through systematic analysis of RNAs with CAG repeats

RNA Biology
CAG repeat tracts occur in both non-coding and translated RNAs, have tended to lengthen throughout evolution, and are thought to enhance neuronal function.
Weronika Pawlik, Magdalena Woźna-Wysocka, Magdalena Jazurek-Ciesiołka, Jarosław Dulski, Tomasz M. Witkoś, Agata Ciołak, Emilia Kozłowska, Edyta Kościańska, Luke C. Bartelt, Julien Philippe, Jarosław Sławek, Paweł M. Świtoński, Albert R. La Spada, Agnieszka Fiszer   +13 more
doaj   +1 more source

Polyglutamine diseases: looking beyond the neurodegenerative universe.

Neural Regen Res, 2021
Mielcarek M, Isalan M.
europepmc   +1 more source

Targeting Hsp70 facilitated protein quality control for treatment of polyglutamine diseases. [PDF]

Cell Mol Life Sci, 2020
Davis AK, Pratt WB, Lieberman AP, Osawa Y.   +3 more
europepmc   +1 more source

Selective silencing of expanded CAG repeats: Chemically modified siRNA advances RNA-based therapies for polyglutamine diseases. [PDF]

Mol Ther Nucleic Acids
Scholten GJ, Hyde JT, Buijsen RAM.
europepmc   +1 more source

Challenges in Polyglutamine Diseases: From Dysfunctional Neuronal Circuitries to Neuron-Specific CAG Repeat Instability. [PDF]

Int J Mol Sci
Deleanu R.
europepmc   +1 more source

Analysis of short tandem repeats linked to polyglutamine diseases from whole-genome sequencing reveals intermediate alleles of <i>HTT</i> associated with an early disease onset in <i>C9orf72</i> carriers. [PDF]

Brain Commun
Barbier M, Gareau T, Camuzat A, Guillaud-Bataille M, Boluda S, Clot F, Araktingi L, Borroni B, van der Zee J, Ghidoni R, Bellini S, Galimberti D, Rossi G, Nacmias B, De la Casa-Fages B, Pastor P, French Clinical and Genetic Research Network on FTD/FTD-ALS and PrevDemALS Study Groups , Latouche M, le Guern E, Durr A, Laquerrière A, Moccia R, Seilhean D, Alvarez V, Le Ber I.   +24 more
europepmc   +1 more source

A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases. [PDF]

RNA, 2018
Zhang Q, Chen ZS, An Y, Liu H, Hou Y, Li W, Lau KF, Koon AC, Ngo JCK, Chan HYE.   +9 more
europepmc   +1 more source