Results 141 to 150 of about 11,293 (160)

[Huntington's disease: trinucleotide disease or polyglutamine disease?].

Rinsho shinkeigaku = Clinical neurology, 1996
Huntington's disease (HD) is associated with expansion of an unstable CAG repeat. Using antibodies against the synthetic peptide corresponding to the sequence of HD gene IT15, we have identified the HD gene product in normal lymphocytes as a approximately 350kDa protein by immunoblot analysis.
K, Ide, N, Nukina, I, Kanazawa
openaire   +1 more source

Polyglutamine diseases and the risk of cancer

The Lancet Oncology, 2012
Mahmoud A, Pouladi, Michael R, Hayden
openaire   +2 more sources

Drosophila Models of Polyglutamine Diseases

2003
H Y Edwin, Chan, Nancy M, Bonini
openaire   +2 more sources

Recent advances in understanding the pathogenesis of polyglutamine diseases: involvement of molecular chaperones and ubiquitin-proteasome pathway

Journal of Chemical Neuroanatomy, 2003
Nihar Ranjan Jana, Nobuyuki Nukina
exaly  

Polyglutamine Diseases: Where does Toxicity Come from? What is Toxicity? Where are We Going?

Journal of Molecular Cell Biology, 2010
Osamu Onodera, Takahashi Toshiaki, Onodera Osamu   +2 more
exaly  

[Polyglutamine diseases].

Nihon rinsho. Japanese journal of clinical medicine, 2012
Kazuhiko, Tagawa, Hitoshi, Okazawa
openaire   +1 more source

Discovery of Therapeutic Approaches for Polyglutamine Diseases: A Summary of Recent Efforts

Medicinal Research Reviews, 2017
Sara Duarte-Silva, Patricia Maciel
exaly  

A novel therapeutic strategy for polyglutamine diseases by stabilizing aggregation-prone proteins with small molecules

Journal of Molecular Medicine, 2005
Motomasa Tanaka, Yoko Machida, Nobuyuki Nukina   +2 more
exaly  

Huntington’s disease: revisiting the aggregation hypothesis in polyglutamine neurodegenerative diseases

FEBS Journal, 2008
Ray Truant, Randy Singh Atwal, Thu Tran   +2 more
exaly  

Polyglutamine Diseases

2018
openaire   +1 more source