Assessment of Phytochemical Composition and Antifungal Activity of Micropropagated Drymis winteri Plants [PDF]
PlantsThe search for sustainable alternatives to synthetic agrochemicals has fueled a growing interest in plant-derived bioactive compounds. Drimys winteri (canelo), a native Chilean tree of significant ethnobotanical importance, is a promising source of ...
Julia Rubio +4 more
doaj +2 more sources
Antibacterial and Antifungal Terpenes from the Medicinal Angiosperms of Asia and the Pacific: Haystacks and Gold Needles [PDF]
Molecules, 2023 This review identifies terpenes isolated from the medicinal Angiosperms of Asia and the Pacific with antibacterial and/or antifungal activities and analyses their distribution, molecular mass, solubility, and modes of action. All data in this review were
Christophe Wiart +10 more
doaj +2 more sources
Application of the herbal chemical marker ranking system (Herb MaRS) to the standardization of herbal raw materials: a case study [PDF]
BMC Complementary Medicine and Therapies, 2023 Introduction Phytochemical standardization of herbal materials involves establishing consistent levels of one or more active ingredients or markers. It ensures the authenticity and quality of herbal materials, extracts, and their products.
Bruhan Kaggwa +7 more
doaj +2 more sources
Frontiers in Pharmacology, 2013 For a long time, the focus of trigeminal chemoperception has rested almost exclusively on TRP channels. However, two-pore domain (K2P) potassium channels have recently been identified as targets for substances associated with typical trigeminal ...
Leopoldo Raul Beltran +7 more
doaj +2 more sources
Exploring Natural Products for New Taste Sensations [PDF]
CHIMIA, 2011 This paper discusses the discovery of uncommon taste or trigeminal active compounds and their associated sensory analysis using human tasting panels with the aim of enhancing the over all taste experience whilst reducing where possible the sugar
Christian Starkenmann +2 more
doaj +3 more sources
Polygodial, the fungitoxic component from the Brazilian medicinal plant Polygonum punctatum [PDF]
Memorias do Instituto Oswaldo Cruz, 2001 Polygonum punctatum (Polygonaceae) is an herb known in some regions of Brazil as "erva-de-bicho" and is used to treat intestinal disorders. The dichloromethane extract of the aerial parts of this plant showed strong activity in a bioautographic assay ...
Tânia Maria de Almeida Alves +3 more
doaj +4 more sources
Antifungal Effect of Polygodial on Botrytis cinerea, a Fungal Pathogen Affecting Table Grapes [PDF]
International Journal of Molecular Sciences, 2017 The antifungal activity of polygodial, a secondary metabolite extracted from Canelo, on mycelial growth of different Botrytis cinerea isolates has been evaluated.
H. Carrasco +5 more
semanticscholar +4 more sources
Practical isolation of polygodial from Tasmannia lanceolata: a viable scaffold for synthesis.
Organic & Biomolecular Chemistry, 2015 Polygodial, a valuable sesquiterpene dialdehyde featuring an epimerizable stereocenter was efficiently extracted and isolated in gram-scale quantities (3.3% w/w) from Tasmannia lanceolata (Tasmanian native pepper) via a recently developed rapid ...
J. Just +4 more
semanticscholar +4 more sources
Polygodial analog induces apoptosis in LNCaP prostate cancer cells
European Journal of Pharmacology, 2018 Prostate cancer (PCa) is the second leading cause of death in American men. The chemotherapeutic treatment strategies are generally not effective and can lead to side effects. Hence, there is an urgent need to identify novel chemotherapeutic agents. The aim of this study was to synthesize and evaluate the therapeutic effects of a synthetic analog of ...
S. Dasari +6 more
semanticscholar +4 more sources
Screening the Tocriscreen™ bioactive compound library in search for inhibitors of Candida biofilm formation. [PDF]
APMIS, 2022 Biofilms formed by Candida species present a significant clinical problem due to the ineffectiveness of many conventional antifungal agents, in particular the azole class. We urgently require new and clinically approved antifungal agents quickly for treatment of critically ill patients.
Abduljalil H +9 more
europepmc +2 more sources