Results 131 to 140 of about 2,253 (158)
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Fabrication of collagen with polyhexamethylene biguanide: A potential scaffold for infected wounds
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2021AbstractBacterial infection remains a great challenge in wound healing, especially in chronic wounds. Multidrug‐resistant organisms are increasing in acute and chronic wound infections, which compromise the chance of therapeutics. Resistance to conventional antibiotics has created an urge to study new approach/system that can effectively control wound ...
Sripriya Ramasamy +6 more
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Cooperativity in the binding of the cationic biocide polyhexamethylene biguanide to nucleic acids
Biochemical and Biophysical Research Communications, 2004The interaction between the broad-spectrum antimicrobial agent, polyhexamethylene biguanide (PHMB), and various nucleic acids was investigated. Titration of either single- or double-stranded 100-bp DNA, or mixed-molecular weight marker DNA, or tRNA with PHMB caused precipitation of a complex between nucleic acid and PHMB in which the nucleotide ...
Michael J Allen, Graham F White
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Polyhexamethylene Biguanide (PHMB) in the Treatment of Experimental Fusarium Keratomycosis
Cornea, 1997We wanted to determine whether topical polyhexamethylene biguanide (PHMB) 0.02% was effective in the treatment of experimental Fusarium keratomycosis in rabbits.Fusarium solani keratomycosis was induced in the eyes of 12 New Zealand white rabbits. The rabbits were treated with PHMB 0.02% in one eye and placebo in the other eye for 6 days.
R G, Fiscella +5 more
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Analysis of polyhexamethylene biguanide in multipurpose contact lens solutions☆
Talanta, 2009The objective of this study was to establish a reasonably simple and reliable method to measure very low concentrations of polyhexamethylene biguanide (PHMB) in multipurpose contact lens solutions (MPSs). By using a weak cation exchange solid phase extraction cartridge to extract the PHMB from MPS, followed by HPLC analysis using an evaporative light ...
Anne D, Lucas +2 more
exaly +3 more sources
The biocide polyhexamethylene biguanide remains an uncommon contact allergen.
Contact Dermatitis, 2007Polyhexamethylene biguanide (PHMB) is used as a preservative in cosmetics and personal care products. Previous studies had shown a frequency of sensitization to PHMB of 0.5% and 0.4% in unselected dermatitis patients. The objective of this study was to determine the current frequency of sensitization to PHMB. From July 2005 until December 2005, a total
Axel Schnuch +2 more
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Effects of Ionic and Surfactant Agents on the Antimicrobial Activity of Polyhexamethylene Biguanide
Eye & Contact Lens: Science & Clinical Practice, 2011Polyhexamethylene biguanide (PHMB) exhibits broad-spectrum antimicrobial activity and is included in multipurpose solutions for contact lenses as a disinfectant. Both cationic and hydrophobic features of PHMB are believed to support its association with microbial cell membranes through electrostatic and hydrophobic interactions.
Ryoji, Yanai +4 more
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American Journal of Ophthalmology, 1993
We developed an intensive treatment regimen of topical neomycin, propamidine, and polyhexamethylene biguanide that was tapered to a maintenance level over a 14- to 28-day period as toxicity developed. Since July 1991, we used this treatment on six eyes of five patients in whom Acanthamoeba keratitis was diagnosed clinically.
J H, Varga +4 more
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We developed an intensive treatment regimen of topical neomycin, propamidine, and polyhexamethylene biguanide that was tapered to a maintenance level over a 14- to 28-day period as toxicity developed. Since July 1991, we used this treatment on six eyes of five patients in whom Acanthamoeba keratitis was diagnosed clinically.
J H, Varga +4 more
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Chlorhexidine or polyhexamethylene biguanide for acanthamoeba keratitis
The Lancet, 1995D V, Seal, J, Hay, C M, Kirkness
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