Efficacy of 0.2% povidone-iodine and 0.1% polyhexamethylene biguanide as preoperative antiseptics in equine ophthalmic procedures. [PDF]
Objective This retrospective study evaluates the efficacy of povidone‐iodine (PI) and polyhexamethylene biguanide (PHMB) as preoperative antiseptics in equine ophthalmic procedures.
Farkas A +4 more
europepmc +3 more sources
Dual Crosslinked Ion-Based Bacterial Cellulose Composite Hydrogel Containing Polyhexamethylene Biguanide [PDF]
Composite bacterial cellulose (BC) based hydrogel with alginate (A) or pectin (P) or alginate and pectin was fabricated via a physical crosslinking technique using calcium chloride (CaCl2) solution and incorporated with polyhexamethylene biguanide (PHMB)
Baramee Chanabodeechalermrung +6 more
doaj +4 more sources
Safety assessment of Polyhexamethylene biguanide [PDF]
OBJECTIVE: The use of antiseptics in the treatment of genital infections has become a systematic alternative to antibiotics. Their use has been also supported for the treatment of virus-induced genital infections.
B. Orrù +3 more
doaj +2 more sources
Protection with a collagen wound matrix containing polyhexamethylene biguanide supports innate wound healing in biofilm-infected porcine wounds. [PDF]
Over 90% of chronic wounds have biofilm infections, making the need for inhibiting reformation of biofilm post‐debridement paramount to support progression through the normal phases of wound healing.
Davis SC +6 more
europepmc +2 more sources
Purified Native Collagen Extracellular Matrix Plus Polyhexamethylene Biguanide Functions as a Barrier to Protect Complex Wounds in an In Vivo Model. [PDF]
Complex surgical wounds often necessitate repeated irrigation and debridement (I&D), resulting in substantial burdens. Purified native collagen extracellular matrix plus polyhexamethylene biguanide (PCMP) is a protective antimicrobial barrier that ...
Nasrallah RA +6 more
europepmc +2 more sources
Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment [PDF]
Acanthamoeba spp. are free-living parasites that can cause severe infections such as granulomatous amoebic encephalitis (GAE) and amoebic keratitis (AK). Polyhexamethylene biguanide (PHMB) is a topical application for AK treatment.
Huang Jian-Ming +7 more
doaj +2 more sources
From Bench to Application: Evaluating the In Vitro and In Vivo Efficacy of a Polyhexamethylene Biguanide and Cross-Linked Hyaluronic Acid-Based Antiseptic Solution. [PDF]
Background/Objectives: In the context of increasing bacterial resistance and the need for effective ophthalmic antiseptics, this study evaluates the antimicrobial efficacy of Corneial MED®, a novel ophthalmic solution containing polyhexamethylene ...
D'Oria F +5 more
europepmc +2 more sources
Determination of polyhexamethylene biguanide hydrochloride
Polyhexamethylene biguanide hydrochloride (PHMB-HCl) is widely used as a disinfectant in personal care products such as cosmetics and toiletries and as a sanitizer in swimming pools. PHMB-HCl possesses marked characteristics of cationic polyelectrolytes.
Masadome Takashi, Hattori Toshiaki
doaj +2 more sources
Surface-Modified Carboxylated Cellulose Nanofiber Hydrogels for Prolonged Release of Polyhexamethylene Biguanide Hydrochloride (PHMB) for Antimicrobial Applications. [PDF]
The surface modification of cellulose nanofibers (CNFs) using a 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO)/sodium bromide (NaBr)/sodium hypochlorite (NaClO) system was successful in improving their hydrophilicity.
O-Chongpian P +6 more
europepmc +2 more sources
Anti-biofilm Activity of Povidone-Iodine and Polyhexamethylene Biguanide: Evidence from In Vitro Tests. [PDF]
Biofilm in chronic wounds is associated with delayed healing and ineffective local treatment. The purpose of this study was to investigate the in vitro anti-biofilm activity of two commonly used antimicrobials, povidone-iodine (PVP-I) and ...
Gryson L +3 more
europepmc +2 more sources

