Results 21 to 30 of about 11,505 (225)

Raman microspectroscopy analysis in the treatment of acanthamoeba keratitis. [PDF]

PLoS ONE, 2013
Acanthamoeba keratitis is a rare but serious corneal disease, often observed in contact lens wearers. Clinical treatment of infected patients frequently involves the use of polyhexamethylene biguanide (PHMB), a polymer used as a disinfectant and ...
Giulia Rusciano, Paola Capriglione, Giuseppe Pesce, Salvatore Del Prete, Gilda Cennamo, David Di Cave, Luciano Cerulli, Antonio Sasso   +7 more
doaj   +8 more sources

Safety of intrastromal injection of polyhexamethylene biguanide and propamidine isethionate in a rabbit model [PDF]

Journal of Advanced Research, 2020
Acanthamoeba keratitis (AK) is difficult to treat, especially when the corneal deep stroma is involved. Intrastromal injection of antimicrobial agents is an effective adjuvant therapy for deep recalcitrant microbial keratitis; however, it has not been ...
Chen-Chee Lim, I-Chen Peng, Yi-Hsun Huang   +2 more
doaj   +2 more sources

Longitudinal Study on the Antimicrobial Performance of a Polyhexamethylene Biguanide (PHMB)-Treated Textile Fabric in a Hospital Environment. [PDF]

Polymers (Basel), 2023
Healthcare workers in the hospital environment are at risk of infection and body fluids such as saliva, bacterial contamination, oral bacteria, etc. directly or indirectly exacerbate this issue. These bio-contaminants, when adhered to hospital linens and
Yim SL, Cheung JW, Cheng IY, Ho LW, Szeto SS, Chan P, Lam YL, Kan CW.   +7 more
europepmc   +2 more sources

Management of Pediatric Superficial Partial-Thickness Burns with Polyhexamethylene Biguanide: Outcomes and Influencing Factors. [PDF]

J Clin Med
Background: In burn care, achieving swift healing with minimal complications remains paramount. This investigation assesses the role of polyhexamethylene biguanide (PHMB) in managing pediatric superficial partial-thickness burns, focusing on the effects ...
Lőrincz A, Nudelman H, Lamberti AG, Garami A, Tiborcz KA, Kovács TZ, Józsa G.   +6 more
europepmc   +2 more sources

Comparative evaluation of chlorhexidine gluconate with alcohol and polyhexamethylene biguanide with Tris-EDTA as antiseptic solutions for pre-operative skin preparation in dogs. [PDF]

Vet World
Background and Aim: Skin antisepsis plays a crucial role in pre-operative skin preparation, with chlorhexidine gluconate and alcohol being historically the preferred choice.
Boonwittaya N, Yurayart C, Udomkusonsri P, Kaewmanee S, Sompaisarnsilp S, Thengchaisri N, Duangurai T.   +6 more
europepmc   +2 more sources

Biguanide Iridium(III) Complexes with Potent Antimicrobial Activity [PDF]

Journal of Medicinal Chemistry, 2018
We have synthesized novel organoiridium(III) antimicrobial complexes containing a chelated biguanide, including the antidiabetic drug metformin. These 16- and 18-electron complexes were characterized by NMR, ESI-MS, elemental analysis, and X-ray ...
Feng Chen, Guy J Clarkson, Christopher G. Dowson   +2 more
exaly   +4 more sources

Polyhexamethylene Biguanide and Nadifloxacin Self-Assembled Nanoparticles: Antimicrobial Effects against Intracellular Methicillin-Resistant Staphylococcus aureus. [PDF]

Polymers (Basel), 2018
The treatment of skin and soft tissue infections caused by methicillin-resistant Staphylococcus aureus (MRSA) remains a challenge, partly due to localization of the bacteria inside the host’s cells, where antimicrobial penetration and efficacy is limited.
Kamaruzzaman NF, Pina MF, Chivu A, Good L.   +3 more
europepmc   +5 more sources

Determination of Polyhexamethylene Biguanide Hydrochloride Using a Lactone-Rhodamine B-Based Fluorescence Optode [PDF]

Molecules, 2020
A new determination method for polyhexamethylene biguanide hydrochloride (PHMB) using a lactone-rhodamine B (L-RB) based fluorescence optode has been developed.
Akane Funaki, Yuta Horikoshi, Teruyuki Kobayashi, Takashi Masadome   +3 more
doaj   +2 more sources

Polyhexamethylene Biguanide Reduces High-Risk Human Papilloma Virus Viral Load in Cervical Cell Samples Derived from ThinPrep Pap Test. [PDF]

Curr Issues Mol Biol
Human papilloma virus (HPV) infection and its progression still represent a great medical challenge worldwide. Clinical evidence has demonstrated the beneficial effects of polyhexamethylene biguanide (PHMB) on HPV clinical manifestations; however ...
Di Fraia L, Babalini C, Calcagno M, Proietti S, Lepore E, Di Fraia P.   +5 more
europepmc   +2 more sources

Development and Evaluation of a Novel Antibacterial Wound Dressing: A Powder Preparation Based on Cross-Linked Pullulan with Polyhexamethylene Biguanide for Hydrogel-Transition in Advanced Wound Management and Infection Control. [PDF]

Polymers (Basel)
As antibiotic resistance increasingly undermines traditional infection management strategies, there is a critical demand for innovative wound care solutions that address these emerging challenges.
Su J, Yu W, Guo X, Wang C, Wang Q, Chen B, Hu Y, Dai H.   +7 more
europepmc   +2 more sources