Results 41 to 50 of about 11,505 (225)

Polyhexanide-Releasing Membranes for Antimicrobial Wound Dressings: A Critical Review

Membranes, 2022
The prevalence of chronic, non-healing skin wounds in the general population, most notably diabetic foot ulcers, venous leg ulcers and pressure ulcers, is approximately 2% and is expected to increase, driven mostly by the aging population and the steady ...
António Jorge Guiomar, Ana M. Urbano
doaj   +1 more source

Toxicological assessment of polyhexamethylene biguanide for water treatment. [PDF]

Interdiscip Toxicol, 2015
Abstract Polyhexamethylene biguanide (PHMB) is an antiseptic with antiviral and antibacterial properties used in a variety of products including wound care dressings, contact lens cleaning solutions, perioperative cleansing products, and swimming pool cleaners.
Asiedu-Gyekye IJ, Mahmood AS, Awortwe C, Nyarko AK.   +3 more
europepmc   +4 more sources

Microsporidial stromal keratitis in an immunocompromised patient: Successful management with medical therapy

Indian Journal of Ophthalmology, 2020
Microsporidial stromal keratitis is refractory to topical drugs and is classically described in immunocompetent hosts. A 55-year-old patient with renal transplant and oral immunosuppressants, presented with a 15-day history of redness, pain, and ...
Amanjot Kaur, Srikant K Sahu, Sanchita Mitra, Sujata Das   +3 more
doaj   +1 more source

Targeting the hard to reach: Challenges and novel strategies in the treatment of intracellular bacterial infections: Targeting intracellular bacteria [PDF]

, 2016
Infectious diseases continue to threaten human and animal health and welfare globally, impacting millions of lives and causing substantial economic loss. The use of antibacterials has been only partially successful in reducing disease impact.
Good, L, Kamaruzzaman, N F, Kendall, S L
core   +1 more source

The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes [PDF]

, 2016
To combat infection and antimicrobial resistance, it is helpful to elucidate drug mechanism(s) of action. Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.
A Gentile, B Spellberg, CE Barry, CR Messick, DJ Dwyer, EE Creppy, EF Palermo, FW O’Grady, G Muller, G Muller, G Rusciano, GS Gordon, J Portugal, JD McCool, JM Boberek, JP Armitage, L Good, LP O’Malley, M Mondhe, MA Kohanski, MJ Allen, MJ Allen, MJ Allen, N Nekhotiaeva, Nakashima, P Broxton, P Broxton, P Broxton, P Erbacher, P Gilbert, R de Vries, R Dryselius, R Firdessa, R Spurio, RF Murphy, S Amoils, S Goh, S Wessels, T Ikeda, T Ikeda, T Kornberg, VB Teif   +41 more
core   +3 more sources

Bacterial Growth Kinetics under a Novel Flexible Methacrylate Dressing Serving as a Drug Delivery Vehicle for Antiseptics [PDF]

, 2013
A flexible methacrylate powder dressing (Altrazeal®) transforms into a wound contour conforming matrix once in contact with wound exudate. We hypothesised that it may also serve as a drug delivery vehicle for antiseptics.
Archibald, Assadian, Axel Kramer, Beldon, Braga, Chen, Christina Forstner, Clark, Cutting, David Leaper, Deitch, Disemond, Eberlein, Fang, Fitzgerald, Henry-Stanley, Hirsch, Johannes Leitgeb, Keith Cutting, Kim, Lalani, Leaper, Leaper, Migliaresi, Minnich, Nathan, Nordmann, Ojan Assadian, Rupert Schuster, Sibbald, Tsou, Vanscheidt, Verena Dosch, Wang, Winter   +34 more
core   +4 more sources

Successful Use of Locally Applied Polyhexamethylene Biguanide as an Adjunct to the Treatment Of Fungal Osteomyelitis

Canadian Journal of Infectious Diseases and Medical Microbiology, 2013
Fungal osteomyelitis is rare in immunocompetent patients and is often difficult to cure, even with optimal medical and surgical management. The authors present two cases of fungal osteomyelitis in which the common swimming pool cleaner, polyhexamethylene
Genevieve Walls, Lisa Noonan, Elizabeth Wilson, David Holland, Simon Briggs   +4 more
doaj   +1 more source

ANTIBACTERIAL ACTIVITY AND QUANTIFICATION OF POLYHEXAMETHTYLENE BIGUANIDE HYDROCHLORIDE IN MUSCULAR TISSUES AND VISCERA OF BROILERS ATIVIDADE ANTIBACTERIANA E QUANTIFICAÇÃO DE CLORIDRATO DE POLIHEXAMETILENO BIGUANIDA (P.H.M.B.) EM TECIDOS MUSCULARES E VÍCERAS DE FRANGOS

Pesquisa Agropecuária Tropical, 2007
<!-- @page { margin: 2cm } --> <p class="western" align="justify">Trials were carried out in order to check the viability of polyhexamethylene biguanide hydrochloride in the control of pathogenic and degenerating bacteria in carcass of ...
Albenones José de Mesquita, Moacir Evandro Lage, Guilherme Roberto de Oliveira, Cristiano Sales Prado   +3 more
doaj   +1 more source

The development of drugs against Acanthamoeba infections [PDF]

, 2016
For the past several decades, there has been little improvement in the morbidity and mortality associated with Acanthamoeba keratitis and Acanthamoeba encephalitis, respectively.
Aqeel, Yousuf, Khan, Naveed Ahmed *, Siddiqui, Ruqaiyyah Bano *   +2 more
core   +1 more source

Research Progress of Common Organic Guanidine Antibacterial Agents

To Chemistry Journal, 2020
Aim: The aim of this study is to investigate the antimicrobial properties of organic guanidine because of their strong alkalinity, high stability, low toxicity and good biological activity.
Hua Li, Yingping Qi, Yongfeng Shen, Hua Li   +3 more
doaj   +2 more sources