Microsomal fractions from pig and calf brain catalyze the enzymatic dephosphorylation of endogenous and exogenous dolichyl monophosphate (Dol-P) (Sumbilla, C. A., and Waechter, C. J. (1985) Methods Enzymol. 111, 471-482). The Dol-P phosphatase (EC 3.1.3.51) has been solubilized by extracting pig brain microsomes with the nonionic detergent Nonidet P-40
D W, Frank, C J, Waechter
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Quantification of dolichol in the human lens with different types of cataracts [PDF]
PURPOSE: To quantify and characterize dolichol species in cataractous and clear human lenses. METHODS: Whole lenses were collected from cadaver eyeballs from the C.H. Nagri Eye Bank and Red Cross Society Eye Bank (Ahmedabad, India). Cataractous nuclei
Alapure, Bhagwat +6 more
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Coordination of Primer Sugar Synthesis with O-antigen Initiation in Rhizobium Etli CE3 [PDF]
All organisms synthesize amidosugars, such as N-acetylglucosamine (GlcNAc), and deoxysugars, such as fucose. They are found in important polysaccharides and glycoconjugates such as glycoproteins.
Li, Tiezheng
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Structural Studies of Phospho-MurNAc-pentapeptide Translocase and Ternary Complex of a NaV C-Terminal Domain, a Fibroblast Growth Factor Homologous Factor, and Calmodulin [PDF]
Phospho-MurNAc-pentapeptide translocase (MraY) is a conserved membrane-spanning enzyme involved in the biosynthesis of bacterial cell walls. MraY generates lipid I by transferring the phospho-MurNAc-pentapeptide to the lipid carrier undecaprenyl ...
Chung, Chih-Pin
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The transfer of mannose from GDP-mannonse to exogenous glycopeptides and simple glycosides has been shown to be carried out by calf thyroid particles (Adamany, A. M., and Spiro, R. G. (1975) J. Biol. Chem. 250, 2830-2841). The present investigation indicates that this mannosylation process is accomplished through two sequential enzymatic reactions. The
A M, Adamany, R G, Spiro
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Glycoprotein Synthesis and Signal Transduction in Schistosoma mansoni [PDF]
Schistosomes are metazoan parasites which live within the blood vessels of man and his livestock. Infection results in a debilitating disease known as schistosomiasis or bilharzia.
Wu, Ke-Ying
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Computing Network of Diseases and Pharmacological Entities through the Integration of Distributed Literature Mining and Ontology Mapping [PDF]
The proliferation of -omics (such as, Genomics, Proteomics) and -ology (such as, System Biology, Cell Biology, Pharmacology) have spawned new frontiers of research in drug discovery and personalized medicine.
Faisal, Fazle Elahi
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A Family of Antibiotics That Evades Resistance by Binding Polyprenyl Phosphates. [PDF]
Rosenzweig AF +4 more
europepmc +1 more source
Medium-Chain Polyprenols Influence Chloroplast Membrane Dynamics In Solanum Lycopersicum [PDF]
The widespread occurrence of polyprenols throughout the plant kingdom is well documented, yet their functional role is poorly understood. These lipophilic compounds are known to be assembled from isoprenoid precursors by a class of enzymes designated as ...
Akhtar, Tariq A. +9 more
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