Results 131 to 140 of about 31,758 (236)

Dereplicative Combination of HPLC/DAD/MS and 2D NMR to Identify Lichexanthone Isomers in Lichen Extracts

open access: yesPhytochemical Analysis, Volume 37, Issue 2, Page 330-343, March 2026.
ABSTRACT Introduction Lichexanthones are the major xanthones found in lichens. They present a high degree of isomerism, which makes their identification tedious. Xanthones are known to occur in lichens according to chemosyndromes, and these compounds act as chemotaxonomic markers.
Solenn Ferron   +5 more
wiley   +1 more source

Corals as Source of Bacteria with Antimicrobial Activity [PDF]

open access: yes, 2008
In this study we examined marine bacteria associated with different corals (Porites lutea, Galaxea fascicularis, Acropora sp. and Pavona sp.) collected from vicinity of Panjang island, Jepara, North Java Sea, Indonesia for their antimicrobial activities ...
Imhoff, J. F. (Johannes)   +3 more
core  

Prokaryotic PfaB is a terminal acyltransferase that determines the final PUFA product

open access: yesProtein Science, Volume 35, Issue 3, March 2026.
Abstract Omega‐3 polyunsaturated fatty acids (PUFAs) are essential for human health due to their numerous beneficial biological properties. These compounds are synthesized in marine bacteria and eukaryotic microalgae by PUFA megasynthases (Pfas), which are evolutionarily related to fatty acid synthases (FAS) and polyketide synthases (PKS). In FAS, PKS,
Nahuel Lofeudo   +5 more
wiley   +1 more source

NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic

open access: yesSmall, Volume 22, Issue 16, 17 March 2026.
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho   +10 more
wiley   +1 more source

Synthetic Biology and Metabolic Engineering of Microalgae for Sustainable Lipid and Terpenoid Production: An Updated Perspective

open access: yesPlant Biotechnology Journal, Volume 24, Issue 3, Page 1359-1376, March 2026.
ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka   +6 more
wiley   +1 more source

Insights into glandular trichome biology from analysis of organ‐specific gene expression programmes in cannabis, hop and tomato

open access: yesThe Plant Journal, Volume 125, Issue 6, March 2026.
Significance Statement This study of three glandular trichome‐producing species (cannabis, hop and tomato) defines tissue‐specific transcriptomic atlases for five organs (trichome, flower, leaf, stem and root), providing co‐expression and gene regulatory networks and identifying candidate regulators of specialised metabolism in trichomes of each ...
Muluneh Tamiru‐Oli   +10 more
wiley   +1 more source

Synthesis of complex intermediates for the study of a dehydratase from borrelidin biosynthesis

open access: yesBeilstein Journal of Organic Chemistry, 2014
Herein, we describe the syntheses of a complex biosynthesis-intermediate analogue of the potent antitumor polyketide borrelidin and of reference molecules to determine the stereoselectivity of the dehydratase of borrelidin polyketide synthase module 3 ...
Frank Hahn   +3 more
doaj   +1 more source

Paxilline negative mutants of Penicillium paxilli generated by heterologous and homologous plasmid integration : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Genetics at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 1998
Using a monoclonal antibody-based ELISA, 600 pAN7-1 plasmid-tagged mutants of Penicillium paxilli were screened for paxilline accumulation and one paxilline negative mutant, YI-20, was identified (Itoh, unpublished data).
Young, Carolyn Anne
core  

Secondary metabolites in Gerbera hybrida [PDF]

open access: yes, 2008
Plants produce a diversity of secondary metabolites, i.e., low-molecular-weight compounds that have primarily ecological functions in plants. The flavonoid pathway is one of the most studied biosynthetic pathways in plants.
Ainasoja, Miia
core  

David Hopwood and the emergence of Streptomyce genetics [PDF]

open access: yes, 2010
Streptomyces spp. are unusual among bacteria in growing as mycelial colonies with sporulating aerial hyphae. They are very important as the source of most of the major antibiotics.
Keith Chater
core   +2 more sources

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