Results 131 to 140 of about 31,758 (236)
ABSTRACT Introduction Lichexanthones are the major xanthones found in lichens. They present a high degree of isomerism, which makes their identification tedious. Xanthones are known to occur in lichens according to chemosyndromes, and these compounds act as chemotaxonomic markers.
Solenn Ferron +5 more
wiley +1 more source
Corals as Source of Bacteria with Antimicrobial Activity [PDF]
In this study we examined marine bacteria associated with different corals (Porites lutea, Galaxea fascicularis, Acropora sp. and Pavona sp.) collected from vicinity of Panjang island, Jepara, North Java Sea, Indonesia for their antimicrobial activities ...
Imhoff, J. F. (Johannes) +3 more
core
Prokaryotic PfaB is a terminal acyltransferase that determines the final PUFA product
Abstract Omega‐3 polyunsaturated fatty acids (PUFAs) are essential for human health due to their numerous beneficial biological properties. These compounds are synthesized in marine bacteria and eukaryotic microalgae by PUFA megasynthases (Pfas), which are evolutionarily related to fatty acid synthases (FAS) and polyketide synthases (PKS). In FAS, PKS,
Nahuel Lofeudo +5 more
wiley +1 more source
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho +10 more
wiley +1 more source
ABSTRACT Microalgae are increasingly recognised as powerful platforms for the sustainable production of lipids and terpenoids, with expanding applications in the food, fuel and biomanufacturing industries. In this updated review, we consolidate and critically assess the most recent advances in synthetic biology and metabolic engineering of key ...
Ty Shitanaka +6 more
wiley +1 more source
Significance Statement This study of three glandular trichome‐producing species (cannabis, hop and tomato) defines tissue‐specific transcriptomic atlases for five organs (trichome, flower, leaf, stem and root), providing co‐expression and gene regulatory networks and identifying candidate regulators of specialised metabolism in trichomes of each ...
Muluneh Tamiru‐Oli +10 more
wiley +1 more source
Synthesis of complex intermediates for the study of a dehydratase from borrelidin biosynthesis
Herein, we describe the syntheses of a complex biosynthesis-intermediate analogue of the potent antitumor polyketide borrelidin and of reference molecules to determine the stereoselectivity of the dehydratase of borrelidin polyketide synthase module 3 ...
Frank Hahn +3 more
doaj +1 more source
Paxilline negative mutants of Penicillium paxilli generated by heterologous and homologous plasmid integration : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Molecular Genetics at Massey University, Palmerston North, New Zealand [PDF]
Using a monoclonal antibody-based ELISA, 600 pAN7-1 plasmid-tagged mutants of Penicillium paxilli were screened for paxilline accumulation and one paxilline negative mutant, YI-20, was identified (Itoh, unpublished data).
Young, Carolyn Anne
core
Secondary metabolites in Gerbera hybrida [PDF]
Plants produce a diversity of secondary metabolites, i.e., low-molecular-weight compounds that have primarily ecological functions in plants. The flavonoid pathway is one of the most studied biosynthetic pathways in plants.
Ainasoja, Miia
core
David Hopwood and the emergence of Streptomyce genetics [PDF]
Streptomyces spp. are unusual among bacteria in growing as mycelial colonies with sporulating aerial hyphae. They are very important as the source of most of the major antibiotics.
Keith Chater
core +2 more sources

