Results 111 to 120 of about 186,140 (231)

Enzyme@Silicone: A Versatile Combo for Robust Synthetic Biocatalysis?

Advanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
Silicone‐based polymers are versatile materials for enzyme immobilization, offering unique advantages such as chemical inertness, thermal stability, and tunable morphology. This review highlights their applications in synthetic biocatalysis, from batch to continuous processes, and addresses key challenges such as mass transport limitations and ...
Marion B. Ansorge‐Schumacher
wiley   +1 more source

A Close Look at a Ketosynthase from a Trans-Acyltransferase Modular Polyketide Synthase [PDF]

, 2014
SummaryThe recently discovered trans-acyltransferase modular polyketide synthases catalyze the biosynthesis of a wide range of bioactive natural products in bacteria.
Kampa, Annette, Kohlhaas, Christoph, Piel, Jörn, Gay, Glen, Oldham, Neil J., Gay, Darren C., Axelrod, Abram J., Jenner, Matthew, Keatinge-Clay, Adrian T.   +8 more
core   +1 more source

Elucidating the Molecular Mechanisms of Vitex negundo L. in Polycystic Ovary Syndrome via Metabolomics‐Driven Network Pharmacology

Biomedical Chromatography, Volume 40, Issue 9, September 2026.
ABSTRACT Polycystic ovary syndrome (PCOS) is a hormonal disorder marked by irregular menstrual cycles, elevated androgen levels, ovarian cysts, hirsutism, acne and other symptoms. While conventional medications such as Metformin and Spironolactone are commonly prescribed, they are often associated with undesirable side effects.
Nishmitha R. Poojary, Neeharika Narisepalli Venkatasai, Kannath U. Sanjay, Supraja M. Kodanch, Padmalatha S. Rai   +4 more
wiley   +1 more source

Insights Into Aggregation‐Delayed Phenotype of Dictyostelium discoideum

Cell Biology International, Volume 50, Issue 9, September 2026.
ABSTRACT Dictyostelium discoideum is a cellular model that has been widely used in cell signal research focusing on different cellular and developmental processes. The unique lifecycle of these cells—which involves switching between vegetative and development phases—makes Dictyostelium a reliable model for investigations in this field.
Sarah Abdulaziz Alamer
wiley   +1 more source

Analysis of the cercosporin polyketide synthase CTB1 reveals a new fungal thioesterase function

, 2012
The polyketide synthase CTB1 is demonstrated to catalyze pyrone formation thereby expanding the known biosynthetic repertoire of thioesterase domains in iterative, non-reducing polyketide synthases ...
Newman, Adam G., Scheerer, Jonathan R., Belecki, Katherine, Vagstad, Anna L.   +3 more
core   +1 more source

Groundnut Improvement for Aflatoxin Resistance: Progress and Opportunities

Food and Energy Security, Volume 15, Issue 5, September/October 2026.
ABSTRACT Groundnut, or peanut, is an industrial oilseed crop that serves the food and feed industries and provides income along the value chain. Pre‐ and post‐harvest aflatoxin contamination, caused by Aspergillus spp., hinders the food and feed value and market opportunities of groundnut products. Developing and deploying aflatoxin‐resistant varieties
Tullu Tadessa Asefa, Hussein Shimelis, Janila Pasupuleti, Seltene Abady Tesfamariam   +3 more
wiley   +1 more source

Evidence for a novel phosphopantetheinyl transferase domain in the polyketide synthase for enediyne biosynthesis [PDF]

, 2008
The polyketide synthase associated with the biosynthesis of enediyne-containing calicheamicin contains a putative phosphopantetheinyl transferase (PPTase) domain.
Zhao-Xun Liang, Liang, Zhao-Xun, Murugan, Elavazhagan, Elavazhagan Murugan   +3 more
core   +1 more source

Microbiome‐mediated chemical communication in insects: Implications for pest management

Pest Management Science, Volume 82, Issue 9, Page 8132-8151, September 2026.
Microbiome–semiochemical interactions involve the following processes: direct microbial synthesis, host gene regulation, precursor biotransformation, microbiome modulation and indirect ecological signaling. Abstract Insects rely on semiochemicals to regulate aggregation, mating, foraging, and host selection. This review synthesizes evidence that insect‐
Ioannis Eleftherianos, Wei Zhang, Amr Mohamed, Rasha K. Al‐Akeel, Abeer M. Alkhaibari, Nemat Keyhani, Guy Smagghe   +6 more
wiley   +1 more source

Advances in large DNA fragment assembly for microbial cell factory engineering

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang, Wenqian Liu, Dongyuan Cheng, Jiazhang Lian, Xian Fu, Yue Shen   +5 more
wiley   +1 more source

Systematic prioritization of candidate genes in camptothecin biosynthesis using multi‐omics and deep learning

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang, Xing Wu, Maria Moreno, Joonseok Oh, Stephen L. Dellaporta, Jason M. Crawford, Farren J. Isaacs   +6 more
wiley   +1 more source