Results 101 to 110 of about 21,069 (236)

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

Plant, Cell &Environment, EarlyView.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo, Adrian Sabater‐Gabriel, Alejandro Garcia, Marta Marina Perez‐Alonso, Rayko Halitschke, M. Estrella Santamaria   +5 more
wiley   +1 more source

A Close Look at a Ketosynthase from a Trans-Acyltransferase Modular Polyketide Synthase [PDF]

, 2014
SummaryThe recently discovered trans-acyltransferase modular polyketide synthases catalyze the biosynthesis of a wide range of bioactive natural products in bacteria.
Kampa, Annette, Kohlhaas, Christoph, Piel, Jörn, Gay, Glen, Oldham, Neil J., Gay, Darren C., Axelrod, Abram J., Jenner, Matthew, Keatinge-Clay, Adrian T.   +8 more
core   +1 more source

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

Plant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor, Kavita Verma, Nishu, Barkat Hussain, Vartika Mathur   +4 more
wiley   +1 more source

Kinetic studies on the actinorhodin polyketide synthase [PDF]

, 2008
The actinorhodin (act) minimal polyketide synthase (PKS) from Streptomyces coelicolor consists of three proteins: an acyl carrier protein (ACP), and two P-ketoacyl ACP synthase components known as KSa and KSp.
Beltran-Alvarez, Pedro
core  

The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains [PDF]

Depsides have garnered substantial interest due to the diverse biological activities exhibited by members of this class. Among these are the antibacterial aquastatins, glycosylated heteromeric depsides formed through the condensation of orsellinic acid ...
Crombie, Andrew, Lau, Ashli, Tan, Yu Pei, Windsor, Fraser, Bracegirdle, Joe, Chooi, Yit-Heng, Chen, Rachel, Piggott, Andrew M., Lacey, Ernest, Sbaraini, Nicolau, Vuong, Daniel, Lacey, Alastair, Kalaitzis, John A.   +12 more
core   +1 more source

Diversity oriented biosynthesis via accelerated evolution of modular gene clusters

Nature Communications, 2017
Reengineering polyketide synthase encoding genes to produce analogues of natural products can be slow and low-yielding. Here the authors use accelerated evolution to recombine the gene cluster for rapid production of rapamycin-related products.
Aleksandra Wlodek, Steve G. Kendrew, Nigel J. Coates, Adam Hold, Joanna Pogwizd, Steven Rudder, Lesley S. Sheehan, Sarah J. Higginbotham, Anna E. Stanley-Smith, Tony Warneck, Mohammad Nur-E-Alam, Markus Radzom, Christine J. Martin, Lois Overvoorde, Markiyan Samborskyy, Silke Alt, Daniel Heine, Guy T. Carter, Edmund I. Graziani, Frank E. Koehn, Leonard McDonald, Alexander Alanine, Rosa María Rodríguez Sarmiento, Suzan Keen Chao, Hasane Ratni, Lucinda Steward, Isobel H. Norville, Mitali Sarkar-Tyson, Steven J. Moss, Peter F. Leadlay, Barrie Wilkinson, Matthew A. Gregory   +31 more
doaj   +1 more source

ACTTS3 Encoding a Polyketide Synthase Is Essential for the Biosynthesis of ACT-Toxin and Pathogenicity in the Tangerine Pathotype of Alternaria alternata

Molecular Plant-Microbe Interactions, 2010
The tangerine pathotype of Alternaria alternata produces host-selective ACT-toxin and causes Alternaria brown spot disease of tangerine and tangerine hybrids.
Y. Miyamoto, A. Masunaka, T. Tsuge, M. Yamamoto, K. Ohtani, T. Fukumoto, K. Gomi, T. L. Peever, Y. Tada, K. Ichimura, K. Akimitsu   +10 more
doaj   +1 more source

Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress

Plant, Cell &Environment, EarlyView.
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee, Madhabi Das, Sanjib Patra, Srijib Chatterjee, Amit Roy, Arunava Mandal   +5 more
wiley   +1 more source

Repurposing a Fully-Reducing Polyketide Synthase for 2-Methyl Guerbet-like Lipid Production [PDF]

In Nature, thousands of diverse and bioactive polyketides are assembled by a family of multifunctional, “assembly line” enzyme complexes called Polyketide Synthases (PKS).
Stephen, McColm, Michael Andrés, Herrera, Fraser, Brown, Joanna, Simpson, Dominic, Campopiano, Reuben, Carr, Louise-Marie, Craigie, David, Clarke   +7 more
core   +1 more source

The Diversity Of Polyketide Synthase Genes From Sugarcane-derived Fungi [PDF]

, 2015
The chemical ecology and biotechnological potential of metabolites from endophytic and rhizosphere fungi are receiving much attention. A collection of 17 sugarcane-derived fungi were identified and assessed by PCR for the presence of polyketide synthase (
Rojas J.D., Lopes M.S.G., Furlan R.L.A., Sette L.D., Padilla G., da Silva L.F., de Araujo W.L.   +6 more
core   +1 more source