Results 101 to 110 of about 186,140 (231)
Diverse Bacterial PKS Sequences Derived From Okadaic Acid-Producing Dinoflagellates
Marine Drugs, 2008 Okadaic acid (OA) and the related dinophysistoxins are isolated from dinoflagellates of the genus Prorocentrum and Dinophysis. Bacteria of the Roseobacter group have been associated with okadaic acid producing dinoflagellates and have been previously ...
Kathleen S. Rein +4 more
doaj
Total Synthesis and Stereochemical Assignment of Alternapyrone
MoleculesAlternapyrone, a bioactive polyketide produced by the fungal host Aspergillus oryzae, is biosynthesized by a polyketide synthase encoded by the alt1-5 gene cluster.
Hui Zhang +5 more
doaj +1 more source
Draft Genome Sequence of a Chitinase-Producing Biocontrol Bacterium, Lysobacter antibioticus HS124
Research in Plant Disease, 2014 Lysobacter antibiocus HS124 is a chitinase-producing rhizobacterium with proven capacities to suppress plant diseases. Bacterial cultures of L. antibioticus HS124 showed strong biocontrol efficacies against various plant diseases compared to those of ...
Brian B. McSpadden Gardener +3 more
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Environmental Toxicology, Volume 41, Issue 10, Page 807-821, October 2026.ABSTRACT Cyanobacterial harmful algal blooms (cyanoHABs) threaten human, animal, and ecosystem health and safety through production of toxic secondary metabolites. Microcystis, a cosmopolitan bloom‐forming cyanobacterial genus, is well‐known for producing hepatotoxic microcystins (MCs), but it can produce many other bioactive cyanopeptides, such as ...
Lauren N. Hart +7 more
wiley +1 more source
Mechanistic Insights Into the Biosynthesis of Pseurotin A in Aspergillus fumigatus
Small StructuresThe biosynthesis of pseurotin A, a fungal metabolite with antibiotic and immunosuppressive properties, involves a group of enzymes, including a polyketide‐nonribosomal peptide synthase (PKS‐NRPS), PsoA, and a bifunctional enzyme, PsoF. PsoA consists of a
Lei Sun +5 more
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Plant, Cell &Environment, Volume 49, Issue 10, Page 7558-7574, October 2026.ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo +5 more
wiley +1 more source
The aquastatin biosynthetic gene cluster encodes a versatile polyketide synthase capable of synthesising heteromeric depsides with diverse alkyl side chains [PDF]
Depsides have garnered substantial interest due to the diverse biological activities exhibited by members of this class. Among these are the antibacterial aquastatins, glycosylated heteromeric depsides formed through the condensation of orsellinic acid ...
Crombie, Andrew +12 more
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Tropinone synthesis via an atypical polyketide synthase and P450-mediated cyclization
Nature Communications, 2018 Tropinone is an intermediate in the biosynthesis of tropane alkaloids. Here, the authors discovered the enzymes AbPYKS and AbCYP82M3, a non-canonical polyketide synthase and a cytochrome P450, that work sequentially to form tropinone from N-methyl-Δ1 ...
Matthew A. Bedewitz +3 more
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Repurposing a Fully-Reducing Polyketide Synthase for 2-Methyl Guerbet-like Lipid Production [PDF]
In Nature, thousands of diverse and bioactive polyketides are assembled by a family of multifunctional, “assembly line” enzyme complexes called Polyketide Synthases (PKS).
Stephen, McColm +7 more
core +2 more sources
Open Life Sciences, 2020 Studies have shown that abundant and various flavonoids accumulate in chili pepper (Capsicum), but there are few reports on the genes that govern chili pepper flavonoid biosynthesis. Here, we report the comprehensive identification of genes encoding type
Kan Delong, Zhao Di, Duan Pengfei
doaj +1 more source