Results 141 to 150 of about 21,069 (236)

Polyketide Trimming Shapes Dihydroxynaphthalene‐Melanin and Anthraquinone Pigments

Advanced Science
Pigments such as anthraquinones (AQs) and melanins are antioxidants, protectants, or virulence factors. AQs from the entomopathogenic bacterium Photorhabdus laumondii are produced by a modular type II polyketide synthase system.
Maximilian Schmalhofer, Anna L. Vagstad, Qiuqin Zhou, Helge B. Bode, Michael Groll   +4 more
doaj   +1 more source

Doctor of Philosophy [PDF]

, 2015
dissertationFungal polyketides are a complex class of natural products with diverse scaffolds. The biosynthesis of these molecules involves the iterative condensation of acetate units using a minimal set of domains on a single polypeptide.
Kakule, Thomas Butanaziba
core  

Molecular characterisation of the acyltransferase-acyl carrier protein interface in a fungal highly reducing polyketide synthase [PDF]

RSC Chem Biol
Foran ME, Ho YTC, Lewandowski JR, Jenner M.   +3 more
europepmc   +2 more sources

Polyketide Synthases

Acta Scientific Microbiology, 2019
openaire   +1 more source

Polyketide synthase-like functionality acquired by plant fatty acid elongase. [PDF]

Sci Adv
Kim H, Park K, Jia H, Huang F, Tang X, Zhong T, Yu W, Riethoven JM, Cahoon RE, Zhang C, Cahoon EB.   +10 more
europepmc   +1 more source

Skeletal editing via multi-step engineering of a modular polyketide synthase. [PDF]

Nat Commun
Kudo K, Hashimoto T, Awakawa T, Zhang L, Nishimura T, Hashimoto J, Kozone I, Kagaya N, Suenaga H, Keatinge-Clay AT, Abe I, Shin-Ya K.   +11 more
europepmc   +1 more source

Small RNA ASpks2 promotes Mycobacterium tuberculosis survival in macrophages via targeting polyketide synthase 2. [PDF]

J Biol Chem
Wu Q, Lu Y, Yuan L, Chen Y, Yang M, Ge F.   +5 more
europepmc   +1 more source

CRISPR/Cas9-Mediated Polyketide Synthase Replacement for High-Yield Biosynthesis and Biological Activity of Milbemycin D. [PDF]

Biology (Basel)
Tao S, Qi H, Luo X, Shen J, He Y, Huang J, Wang R, Zhang S, Gao Y, Wang J, Zhang L.   +10 more
europepmc   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium. [PDF]

FEBS Open Bio
Yamashita TR, Usuki T, Kay RR, Saito T.
europepmc   +1 more source

Acetyl- and malonyl-CoA availability drive EPA selectivity in polyketide synthase-engineered Yarrowia lipolytica. [PDF]

Microb Cell Fact
Qi H, Ries F, Jovanovic Gasovic S, Dietrich D, Gemperlein K, Müller R, Kohlstedt M, Wittmann C.   +7 more
europepmc   +1 more source