Results 111 to 120 of about 15,660 (211)
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo +5 more
wiley +1 more source
Evidence for an iterative module in chain elongation on the azalomycin polyketide synthase
The assembly-line synthases that produce bacterial polyketide natural products follow a modular paradigm in which each round of chain extension is catalysed by a different set or module of enzymes.
Hui Hong +5 more
doaj +1 more source
The rough lemon pathotype of Alternaria alternata produces host-selective ACR-toxin and causes Alternaria leaf spot disease of rough lemon (Citrus jambhiri). The structure of ACR-toxin I (MW = 496) consists of a polyketide with an α-dihydropyrone ring in
Y. Izumi +9 more
doaj +1 more source
Potential of endophytic Beauveria bassiana against Coraebus (Coleoptera: Buprestidae) oak borers
This study demonstrates that an endophytic, oak‐associated strain of Beauveria bassiana exhibits adaptations to Quercus plants and potential against Coraebus boring beetles, supported by distinctive biological traits. Abstract BACKGROUND Oak borers in the genus Coraebus, including the bark‐ and the wood‐boring beetles C. florentinus and C. undatus, are
Walaa Morda +5 more
wiley +1 more source
Structure and function of the geldanamycin amide synthase from Streptomyces hygroscopicus
Amide synthases catalyze the formation of macrolactam rings from aniline-containing polyketide-derived seco-acids as found in the important class of ansamycin antibiotics.
Wiebke Ewert +9 more
doaj +1 more source
Engineered polyketides: Synergy between protein and host level engineering [PDF]
Metabolic engineering efforts toward rewiring metabolism of cells to produce new compounds often require the utilization of non-native enzymatic machinery that is capable of producing a broad range of chemical functionalities.
Bailey, Constance B. +4 more
core +2 more sources
This review elucidates the molecular mechanisms of algicidal bacteria, highlighting critical behaviours like chemotaxis, quorum sensing and extracellular vesicle release. It details how these actions disrupt algal cellular integrity, photosynthesis and calcium homeostasis, providing a theoretical foundation for controlling harmful algal blooms ...
Jiaxin Wang, Binfu Xu, Lixing Huang
wiley +1 more source
Template-directed biopolymerization: tape-copying Turing machines
DNA, RNA and proteins are among the most important macromolecules in a living cell. These molecules are polymerized by molecular machines. These natural nano-machines polymerize such macromolecules, adding one monomer at a time, using another linear ...
Chowdhury, Debashish, Sharma, Ajeet K.
core +1 more source
Accessing Nature’s diversity through metabolic engineering and synthetic biology [PDF]
In this perspective, we highlight recent examples and trends in metabolic engineering and synthetic biology that demonstrate the synthetic potential of enzyme and pathway engineering for natural product discovery.
Edgar, Steven McBride +3 more
core +2 more sources
Identification of Natural Isonitriles Through Ligation to an Azomethine Imine Probe
The azomethine imine (AMI)–isonitrile (NC) ligation allowed for the chemoselective detection of natural isonitriles in bacteria and fungi. The reactivity‐based screening establishes a new stereogenic center, thereby allowing for facile distinction between chiral and achiral isonitriles. The work also unraveled a unique reactivity of isonitriles bearing
Maurice P. Biedermann +6 more
wiley +1 more source

