Results 51 to 60 of about 27,763 (265)

Polyketides from the Mangrove-Derived Endophytic Fungus Nectria sp. HN001 and Their α-Glucosidase Inhibitory Activity

Marine Drugs, 2016
Four new polyketides: nectriacids A–C (1–3) and 12-epicitreoisocoumarinol (4), together with three known compounds: citreoisocoumarinol (5), citreoisocoumarin (6), and macrocarpon C (7) were isolated from the culture of the endophytic fungus Nectria sp ...
Hui Cui, Yayue Liu, Yang Nie, Zhaoming Liu, Senhua Chen, Zhengrui Zhang, Yongjun Lu, Lei He, Xishan Huang, Zhigang She   +9 more
doaj   +1 more source

Bioinspired iterative synthesis of polyketides [PDF]

Frontiers in Chemistry, 2015
Diverse array of biopolymers and second metabolites (particularly polyketide natural products) has been manufactured in nature through an enzymatic iterative assembly of simple building blocks. Inspired by this strategy, molecules with inherent modularity can be efficiently synthesized by repeated succession of similar reaction sequences.
Zheng, Kuan, Xie, Changmin, Hong, Ran
openaire   +3 more sources

Nidulantes of Aspergillus (Formerly Emericella): A Treasure Trove of Chemical Diversity and Biological Activities

Metabolites, 2020
The genus Emericella (Ascomycota) includes more than thirty species with worldwide distribution across many ecosystems. It is considered a rich source of diverse metabolites.
Najla Ali Alburae, Afrah E. Mohammed, Hajer Saeed Alorfi, Adnan Jaman Turki, Hani Zakaria Asfour, Walied Mohamed Alarif, Ahmed Abdel-Lateff   +6 more
doaj   +1 more source

Polyketides from the Halotolerant Fungus Myrothecium sp. GS-17 [PDF]

, 2013
Two new polyketides, myrothecol (1) and 5-hydroxy-3-methyl-4-(1- hydroxylethyl)-furan-2(5H)-one (2), were isolated from the fermentation broth of the halotolerant fungus Myrothecium sp.
Hua-Qi Pan, Hui-Ming Hua, Jiao Bai, Jing Zhu, Li-Ping Guan, Song-Ya Zhang, Tao Liu, Ventosa, Xin Wu, Zhan-Lin Li   +9 more
core   +2 more sources

Polyketides from Plakortis Sponges around Caribbean Coastal Regions: Collection, Isolation, Characterization, and Bioactivity

Coasts
The coastal region of the Caribbean is notable for the chemical diversity found in its sponge products, resulting in the biosynthesis of a range of natural marine products, including polyketides.
Raúl R. Rodríguez-Berríos, Jeremy A. Rodríguez-Vargas, Francisco Colón-Cartagena, Ulises Maldonado-Silva, Yermarie W. Ortiz-Colón, Alejandro Escalante-Castaneda, Arianthony Conde-González, Keiry Y. Álamo-Diverse   +7 more
doaj   +1 more source

Large-Scale Bioinformatics Analysis of Bacillus Genomes Uncovers Conserved Roles of Natural Products in Bacterial Physiology

mSystems, 2017
Bacteria possess an amazing capacity to synthesize a diverse range of structurally complex, bioactive natural products known as specialized (or secondary) metabolites.
Kirk J. Grubbs, Rachel M. Bleich, Kevin C. Santa Maria, Scott E. Allen, Sherif Farag, Elizabeth A. Shank, Albert A. Bowers   +6 more
doaj   +1 more source

Elucidating the Diversity and Potential Function of Nonribosomal Peptide and Polyketide Biosynthetic Gene Clusters in the Root Microbiome

mSystems, 2020
Polyketides (PKs) and nonribosomal peptides (NRPs) are two microbial secondary metabolite (SM) families known for their variety of functions, including antimicrobials, siderophores, and others.
Barak Dror, Zongqiang Wang, Sean F. Brady, Edouard Jurkevitch, Eddie Cytryn   +4 more
doaj   +1 more source

Draft Genome Sequence of Streptomyces phaeoluteigriseus DSM41896 [PDF]

, 2017
The draft genome for the type strain Streptomyces phaeoluteigriseus DSM41896 (ISP 5182) is reported. It was classified as a member of the Streptomyces violaceusniger clade; however, a polyphasic study showed it was a separate species based on its ...
Aziz, Bankevich, Bosi, Figueras, Goodfellow, Gurevich, Kurtz, Medema, Overbeek, Richter, Shirling   +10 more
core   +1 more source

Exploring the Roles of Tuna‐Associated Acinetobacter sp. YFT067: Implications for Host Health and Metabolism

Animal Research and One Health, EarlyView.
This study firstly isolated a tuna‐derived gut probiotic Acinetobacter seifertii YFT067. Dietary administration of YFT067 played significant roles in promoting growth performance, SCFAs production, lipid absorption, and metabolism of the host, indicating YFT067 as a promising probiotic candidate for enhancing tuna aquaculture productivity through ...
Ying Zou, Hai Huang, Qiongyao Fu, Zhiyuan Lu, Zhiqiang Guo   +4 more
wiley   +1 more source

Actinomycete-Derived Polyketides as a Source of Antibiotics and Lead Structures for the Development of New Antimicrobial Drugs

Antibiotics, 2019
Actinomycetes are remarkable producers of compounds essential for human and veterinary medicine as well as for agriculture. The genomes of those microorganisms possess several sets of genes (biosynthetic gene cluster (BGC)) encoding pathways for the ...
Helene L. Robertsen, Ewa M. Musiol-Kroll   +1 more
doaj   +1 more source