Results 61 to 70 of about 20,629 (261)
mSystems, 2020 Polyketides (PKs) and nonribosomal peptides (NRPs) are two microbial secondary metabolite (SM) families known for their variety of functions, including antimicrobials, siderophores, and others.
Barak Dror +4 more
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Molecules, 2019 A new polyketide erubescensoic acid (1), and the previously reported xanthonopyrone, SPF-3059-26 (2), were isolated from the uninvestigated fractions of the ethyl acetate crude extract of the marine sponge-associated fungus Penicillium erubescens ...
Decha Kumla +8 more
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Bioactive Compounds from Terrestrial and Marine-Derived Fungi of the Genus Neosartorya
Molecules, 2022 Fungi comprise the second most species-rich organism group after that of insects. Recent estimates hypothesized that the currently reported fungal species range from 3.5 to 5.1 million types worldwide. Fungi can grow in a wide range of habitats, from the
Joana D. M. de Sá +3 more
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The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases
Molecules, 2011 Polyketides are a diverse class of medically important natural products whose biosynthesis is catalysed by polyketide synthases (PKSs), in a fashion highly analogous to fatty acid biosynthesis. In modular PKSs, the polyketide chain is assembled by the successive condensation of activated carboxylic acid-derived units, where chain extension occurs with ...
Kwan, David H., Schulz, Frank
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The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase [PDF]
Chemical Communications, 2017 Thiotetronate polyketide assembly by an unusual iterative synthase is reconstructed via in vitro enzymology and chemical probes.
Marie E. Yurkovich +4 more
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Biosynthesis of fungal polyketides
, 2018 Fungal polyketides comprise of a large group of structurally diverse compounds with a wide range of biological activities. These compounds are biosynthesised by Type I iterative polyketide synthases (PKS) which can be further defined as non-reducing (nr),
Skellam, Elizabeth +5 more
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Comprehensive Description of Fusarium graminearum Pigments and Related Compounds
Foods, 2018 Several studies have explored in depth the biochemistry and genetics of the pigments present in Fusarium graminearum, but there is a need to discuss their relationship with the mold’s observable surface color pattern variation throughout its ...
Edgar Cambaza
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Structural control of polyketide formation in plant-specific polyketide synthases [PDF]
Chemistry & Biology, 2000 Polyketide synthases (PKSs) generate molecular diversity by utilizing different starter molecules and by controlling the final length of the polyketide. Although exploitation of this mechanistic variability has produced novel polyketides, the structural foundation of this versatility is unclear. Plant-specific PKSs are essential for the biosynthesis of
Jez, Joseph M +5 more
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Molecules, 2009 Most Annonaceous acetogenins are characterized by between one and three THF ring(s) with one or two flanking hydroxyl group(s) in the center of a C32/34 fatty acid, and the terminal carboxylic acid is combined with a 2-propanol unit to form an α,β ...
Naoto Kojima, Tetsuaki Tanaka
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Biosynthesis of Polyketides in <em>Streptomyces</em>
, 2018 Polyketides are large group of secondary metabolites that have notable variety in their structure and function. Polyketides exhibit a wide range of bioactivities such as antibacterial, antifungal, anticancer, antiviral, immune-suppressing, anti ...
Chandra Risdian
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