Results 41 to 50 of about 27,763 (265)
Polyketides are secondary metabolites mainly found in aerobic organisms with wide applications in medicine and agriculture. Here, the authors uncover new polyketides native to the anaerobic bacterium Clostridium acetobutylicum and show their role in ...
Nicolaus A. Herman +5 more
doaj +1 more source
Total synthesis of decarboxyaltenusin
The total synthesis of decarboxyaltenusin (5’-methoxy-6-methyl-[1,1’-biphenyl]-3,3’,4-triol), a toxin produced by various mold fungi, has been achieved in seven steps in a yield of 31% starting from 4-methylcatechol and 1-bromo-3,5-dimethoxybenzene ...
Lucas Warmuth +5 more
doaj +1 more source
The synthesis of the polyketide section present in the potently cytotoxic marine cyclodepsipeptide jasplakinolide and related natural products, geodiamolides and seragamides, is reported.
Jan Hendrik Lang, Thomas Lindel
doaj +1 more source
Synthetic biology—putting engineering into biology [PDF]
Synthetic biology is interpreted as the engineering-driven building of increasingly complex biological entities for novel applications. Encouraged by progress in the design of artificial gene networks, de novo DNA synthesis and protein engineering, we ...
Heinemann, Matthias,, Panke, Sven,
core +1 more source
Structural control of polyketide formation in plant-specific polyketide synthases [PDF]
Polyketide synthases (PKSs) generate molecular diversity by utilizing different starter molecules and by controlling the final length of the polyketide. Although exploitation of this mechanistic variability has produced novel polyketides, the structural foundation of this versatility is unclear. Plant-specific PKSs are essential for the biosynthesis of
Jez, Joseph M +5 more
openaire +2 more sources
Steroidi i poliketidi iz kore biljke Uvaria hamiltonii [PDF]
Two known steroids, stigmasterol and 6beta-hydroxystigmasta-4,22-dien-3-one (1) and two unusual polyketides, cis-4-hydroxymellein (2) and trans-4-hydroxymellein (3) were isolated from the stem bark of Uvaria hamiltonii.
CHOUDHURY M. HASAN +3 more
core +2 more sources
Foliar spraying of CS‐CDs can form a film on the leaves of Brassica rapa, effectively reducing the enrichment and absorption of PS in the leaves, while increasing the biomass and nutrient content of the plants. In addition, CS‐CDs can also enrich the interfoliar microbial community and activate the plant's own defense metabolic pathways.
Beibei Zhao +6 more
wiley +1 more source
Tobacco bacterial wilt caused by Ralstonia solanacearum is one of the most devastating diseases. Microbial keystone taxa were proposed as promising targets in plant disease control.
Xiaona Sui +8 more
doaj +1 more source
The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase [PDF]
Thiotetronate polyketide assembly by an unusual iterative synthase is reconstructedvia in vitroenzymology and chemical probes.
Marie E. Yurkovich +4 more
openaire +3 more sources
Polyenylpyrrole Derivatives Inhibit NLRP3 Inflammasome Activation and Inflammatory Mediator Expression by Reducing Reactive Oxygen Species Production and Mitogen-Activated Protein Kinase Activation [PDF]
10.1371/journal.pone.0076754PLoS ONE810 ...
A Halle +53 more
core +2 more sources

