Results 41 to 50 of about 15,852 (221)
mSystems, 2017 Bacteria possess an amazing capacity to synthesize a diverse range of structurally complex, bioactive natural products known as specialized (or secondary) metabolites.
Kirk J. Grubbs +6 more
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Metabolites, 2020 The genus Emericella (Ascomycota) includes more than thirty species with worldwide distribution across many ecosystems. It is considered a rich source of diverse metabolites.
Najla Ali Alburae +6 more
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Bioactive Compounds from Terrestrial and Marine-Derived Fungi of the Genus Neosartorya
Molecules, 2022 Fungi comprise the second most species-rich organism group after that of insects. Recent estimates hypothesized that the currently reported fungal species range from 3.5 to 5.1 million types worldwide. Fungi can grow in a wide range of habitats, from the
Joana D. M. de Sá +3 more
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Antibiotics, 2019 Actinomycetes are remarkable producers of compounds essential for human and veterinary medicine as well as for agriculture. The genomes of those microorganisms possess several sets of genes (biosynthetic gene cluster (BGC)) encoding pathways for the ...
Helene L. Robertsen +1 more
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mSystems, 2020 Polyketides (PKs) and nonribosomal peptides (NRPs) are two microbial secondary metabolite (SM) families known for their variety of functions, including antimicrobials, siderophores, and others.
Barak Dror +4 more
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Structural control of polyketide formation in plant-specific polyketide synthases [PDF]
Chemistry & Biology, 2000 Polyketide synthases (PKSs) generate molecular diversity by utilizing different starter molecules and by controlling the final length of the polyketide. Although exploitation of this mechanistic variability has produced novel polyketides, the structural foundation of this versatility is unclear. Plant-specific PKSs are essential for the biosynthesis of
Jez, Joseph M +5 more
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Molecules, 2019 A new polyketide erubescensoic acid (1), and the previously reported xanthonopyrone, SPF-3059-26 (2), were isolated from the uninvestigated fractions of the ethyl acetate crude extract of the marine sponge-associated fungus Penicillium erubescens ...
Decha Kumla +8 more
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Comprehensive Description of Fusarium graminearum Pigments and Related Compounds
Foods, 2018 Several studies have explored in depth the biochemistry and genetics of the pigments present in Fusarium graminearum, but there is a need to discuss their relationship with the mold’s observable surface color pattern variation throughout its ...
Edgar Cambaza
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The Stereochemistry of Complex Polyketide Biosynthesis by Modular Polyketide Synthases
Molecules, 2011 Polyketides are a diverse class of medically important natural products whose biosynthesis is catalysed by polyketide synthases (PKSs), in a fashion highly analogous to fatty acid biosynthesis. In modular PKSs, the polyketide chain is assembled by the successive condensation of activated carboxylic acid-derived units, where chain extension occurs with ...
Kwan, David H., Schulz, Frank
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The polyketide backbone of thiolactomycin is assembled by an unusual iterative polyketide synthase [PDF]
Chemical Communications, 2017 Thiotetronate polyketide assembly by an unusual iterative synthase is reconstructed via in vitro enzymology and chemical probes.
Marie E. Yurkovich +4 more
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