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The Polymerase Chain Reaction and Branching Processes
Journal of Computational Biology, 1995We construct a mathematical model for the polymerase chain reaction and its mutations using the theory of branching processes. Under this model we study the number of mutations in a randomly chosen sequence after n PCR cycles. A method for estimating the mutation is proposed and the variance of this estimator is studied.
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Understanding the Polymerase Chain Reaction
Transfusion Medicine Reviews, 1994H, Ni, M A, Blajchman
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The Basic Polymerase Chain Reaction
Cold Spring Harbor Protocols, 2006Joseph, Sambrook, David W, Russell
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Expanded Genetic Alphabets in the Polymerase Chain Reaction
Angewandte Chemie - International Edition, 2010, Fei Chen
exaly
Graphene Enhances the Specificity of the Polymerase Chain Reaction
Small, 2012Liping Sun, Jian Weng, Guoming Huang
exaly

