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Introduction to the Polymerase Chain Reaction
2003The polymerase chain reaction (PCR) is an in vitro method for the amplification of DNA that was introduced in 1985 (1). The principle of the PCR is elegantly simple but the resulting method is extremely powerful. The adoption of the thermostable Taq polymerase in 1988 greatly simplifies the process and enables the automatron of PCR (2).
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The Polymerase Chain Reaction and Branching Processes
Journal of Computational Biology, 1995We construct a mathematical model for the polymerase chain reaction and its mutations using the theory of branching processes. Under this model we study the number of mutations in a randomly chosen sequence after n PCR cycles. A method for estimating the mutation is proposed and the variance of this estimator is studied.
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Understanding the Polymerase Chain Reaction
Transfusion Medicine Reviews, 1994H, Ni, M A, Blajchman
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The Basic Polymerase Chain Reaction
Cold Spring Harbor Protocols, 2006Joseph, Sambrook, David W, Russell
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Expanded Genetic Alphabets in the Polymerase Chain Reaction
Angewandte Chemie - International Edition, 2010Steven A. Benner, Fei Chen
exaly
Quantitative Measurement of BCR/Abl Transcripts Usingreal-Time Polymerase Chain Reaction
Annals of Oncology, 2002Hagop Kantarjian, Moshe Talpaz, M S Lee
exaly

