Results 91 to 100 of about 59,311 (300)

Engineering Resatorvid‐Loaded Sub‐Microgels of Epigallocatechin‐3‐gallate/Hyaluronic Acid to Treat Acute Lung Injury

Advanced Healthcare Materials, EarlyView.
This study presents HAEP@Res sub‐microgels as a lung‐targeted delivery system integrating antioxidant activity with anti‐inflammatory therapy. The sub‐microgels demonstrate excellent biocompatibility, efficiently scavenge intracellular ROS, and downregulate pro‐inflammatory cytokines and genes in a Bleo‐induced ALI mouse model. These findings highlight
Bo Liu, Olawale Alimi Alimi, Benjamin Stearnes, Svetlana Romanova, Brady J. Sillman, Mena Asha Krishnan, Kristina Bailey, Benson J. Edagwa, Huanhuan Joyce Chen, Han‐jun Wang, Bin Duan   +10 more
wiley   +1 more source

Advances in Polymer Micelles for Cancer Therapy: From Conventional to Smart Delivery Systems

Pharmaceutics
Polymeric micelles have become a versatile and clinically significant class of nanocarriers for cancer therapy. They effectively solubilize poorly water-soluble anticancer drugs, extend their circulation in the bloodstream, and promote accumulation in ...
Rayna Georgieva Bryaskova, Krasimir Georgiev Staykov, Damyan Stoyanov Ganchev   +2 more
doaj   +1 more source

Heirarchical Self Assembly: Self Organized nano-structures in a nematically ordered matrix of self assembled polymeric chains

, 2014
We report many different nano-structures which are formed when model nano-particles of different sizes (diameter {\sigma} n ) are allowed to aggregate in a background matrix of semi-flexible self assembled polymeric worm like micellar chains.
Chatterji, Apratim, Mubeena, Shaikh
core   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle

Pharmaceutics, 2018
Low aqueous solubility of drug causes difficulties in preparation and inconvenience of administration. Polymeric micelles of fluorometholone (FML) using solid dispersion technique were prepared to develop an eye drop formulation with enhanced water ...
Gyubin Noh, Taekwang Keum, Jo-Eun Seo, Jaewoong Choi, Bastola Rakesh, Lamichhane Shrawani, Byoungduck Park, Young Wook Choi, Sangkil Lee   +8 more
doaj   +1 more source

Toy amphiphiles on the computer: What can we learn from generic models?

, 2009
Generic coarse-grained models are designed such that they are (i) simple and (ii) computationally efficient. They do not aim at representing particular materials, but classes of materials, hence they can offer insight into universal properties of these ...
Bernardes, Bhattacharya, Brannigan, Brannigan, Brannigan, Brannigan, Carmesin, Cooke, Cordomi, de Meyer, de Planque, de Vries, de Vries, Doi, Düchs, Düchs, Farago, Fraaije, Fraaije, Fraser, Fredrickson, Fredrickson, Ganesan, Gennis, Gompper, Grest, Gunn, Guo, Guo, Guo, Guo, Götz, Haas, Haas, Haas, Halley, Harroun, He, He, He, He, Helfand, Helfand, Helfrich, Huang, Israelachvili, Izvekov, Jain, Karaborni, Katsaras, Killian, Komura, Koynova, Koynova, Kranenburg, Kranenburg, Kranenburg, Larson, Larson, Lei, Lenz, Lenz, Li, Lindahl, Linhananta, Loison, Loison, Loison, Marrink, Marsh, Matsen, Matsen, Matsen, Maurits, Maurits, Müller, Müller, Müller-Plathe, Noguchi, Noguchi, Pabst, Pochan, Safran, Schmid, Schmid, Schmid, Schmid, Schmid, Schmid, Schmid, Schmidt, Sengupta, Sevink, Sevink, Sharpe, Shen, Shillcock, Shillcock, Shull, Shull, Smit, Smit, Smith, Soddemann, Soddemann, Stadler, Stadler, Sun, Tardieu, Tenchov, Varandas, Venturoli, Venturoli, von Gottberg, von Gottberg, Wang, Werner, Werner, Werner, West, Wheeler, Whitmore, Yamamoto, Zhang, Zhang   +124 more
core   +1 more source

Potential "ways of thinking" about the shear-banding phenomenon [PDF]

, 2011
Shear-banding is a curious but ubiquitous phenomenon occurring in soft matter. The phenomenological similarities between the shear-banding transition and phase transitions has pushed some researchers to adopt a 'thermodynamical' approach, in opposition ...
Fardin, M. A., Gay, C., Grégoire, G., Lerouge, S., McKInley, G. H., Ober, T. J.   +5 more
core   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

PEG-Derivatized Dual-Functional Nanomicelles for Improved Cancer Therapy

Frontiers in Pharmacology, 2019
Polymeric micelles have attracted considerable attention for effective delivery of poorly water-soluble cancer drugs. Polyethylene glycol (PEG), which has been approved for human use by the US Food and Drug Administration, is the most commonly used ...
Yanping Li, Ting Zhang, Qinhui Liu, Jinhan He, Jinhan He   +4 more
doaj   +1 more source

Controlled Nanoparticle Formation by Diffusion Limited Coalescence [PDF]

, 2012
Polymeric nanoparticles (NPs) have a great application potential in science and technology. Their functionality strongly depends on their size. We present a theory for the size of NPs formed by precipitation of polymers into a bad solvent in the presence
Lebouille, J. G. J. L., Slot, J. J. M., Stepanyan, R., Stuart, M. A. Cohen, Tuinier, R.   +4 more
core   +4 more sources