Results 241 to 250 of about 59,311 (300)
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2014
Polymeric micelles are self-assemblies of amphiphilic polymers, which exhibit greater thermodynamic and kinetic stability than micelles of classical surfactants. Block copolymers can be synthesized to bear a variety of chemical functionalities both in the hydrophobic and in the hydrophilic blocks, which enables the preparation of micelles with diverse ...
Nobuhiro Nishiyama, Hiroyasu Takemoto
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Polymeric micelles are self-assemblies of amphiphilic polymers, which exhibit greater thermodynamic and kinetic stability than micelles of classical surfactants. Block copolymers can be synthesized to bear a variety of chemical functionalities both in the hydrophobic and in the hydrophilic blocks, which enables the preparation of micelles with diverse ...
Nobuhiro Nishiyama, Hiroyasu Takemoto
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Photo-responsive polymeric micelles
Soft Matter, 2014Photo-responsive polymeric micelles with different photo-reaction mechanisms and their applications in various fields have been discussed.
Yu, Huang +3 more
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Drug Loading of Polymeric Micelles
Pharmaceutical Research, 2012To gain mechanistic insights into drug loading and lyophilization of polymeric micelles.PEGylated poly-4-(vinylpyridine) micelles were loaded with dexamethasone. Three different methods were applied and compared: O/W emulsion, direct dialysis, cosolvent evaporation.
Miller, Tobias +6 more
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Continuous processing of paclitaxel polymeric micelles
International Journal of Pharmaceutics, 2021A continuous polymeric micelle processing platform was successfully developed, which eliminated batch-to-batch variation in critical quality attributes (for example, size and polydispersity that are typically associated with batch processing). A continuous precipitation process was achieved via coaxial turbulent jet in co-flow technology allowing ...
Anand Gupta +3 more
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Nano Today, 2012
Summary Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano-scale aggregates form spontaneously in aqueous solution and can be used to overcome drug insolubility and increase circulation half life. Self-assembled polymeric micelles are dynamic in nature; thermodynamics defines how the system acts as micelles ...
Shawn C. Owen +2 more
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Summary Polymeric micelles provide a platform that can be carefully tuned for drug delivery. The nano-scale aggregates form spontaneously in aqueous solution and can be used to overcome drug insolubility and increase circulation half life. Self-assembled polymeric micelles are dynamic in nature; thermodynamics defines how the system acts as micelles ...
Shawn C. Owen +2 more
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Polymeric Micelles with Tunable Channels
Macromolecular Bioscience, 2010AbstractThis article describes a novel type of polymeric micelles with tunable channels (PMTC), which are usually composed of a common core and a mixed shell of two different kinds of polymer chains with at least one of them being stimuli‐responsive. Phase separation of the mixed shell upon stimuli results in channels between the micelle core and the ...
Rujiang, Ma, Linqi, Shi
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Polymeric Micelles for Drug Delivery
Current Pharmaceutical Design, 2006Polymeric micelles are nanoscopic core/shell structures formed by amphiphilic block copolymers. Both the inherent and modifiable properties of polymeric micelles make them particularly well suited for drug delivery purposes. An emphasis of this review has been placed on both the description and characterization techniques of the physical properties of ...
S R, Croy, G S, Kwon
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Rupturing Polymeric Micelles with Cyclodextrins
Langmuir, 2006Small-angle neutron scattering has been used to investigate the associative structures formed by triblock copolymers of poly(ethylene oxide) (PEO)-polypropylene oxide (PPO)-poly(ethylene oxide) (PEO) (also known as Pluronics) and to monitor the structural changes occurring upon complexation with heptakis(2,6-di-O-methyl)-beta-cyclodextrin (hbeta-CD ...
Joseph, J +3 more
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Polymeric Micelles with Mesoporous Cores
ACS Macro Letters, 2013Mesoporous polymer nanoparticles containing pores with sizes ranging from 2 to 50 nm are attractive for wide applications, such as catalysis, drug delivery, and separations. On the basis of nanometer-sized phase separation and cleavage reaction in the micellar cores, polymeric micelles with mesoporous cores are prepared in this research.
Yue, Zhang +3 more
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