Results 91 to 100 of about 303,582 (318)

Biodiversity of 52 chicken populations assessed by microsatellite typing of DNA pools [PDF]

, 2003
In a project on the biodiversity of chickens funded by the European Commission (EC), eight laboratories collaborated to assess the genetic variation within and between 52 populations from a wide range of chicken types.
Kari Elo, Kirzhner Valery M, Barre-Dirie, Asili, Korol, Abraham B., Kirzhner, Valery M., Marcus W. Feldman, Kirzhner, Valery M, WEIGEND, S., Burke, T., Michèle Tixier-Boichard, Dirie, A.B., Freidlin, Paul J, Pippa Thomson, Korol, Abraham B, Burke, Terry, FELDMAN, M.W., Feldman Marcus W, Thomson, Pippa; id_orcid, Weigend, Steffen, Freidlin Paul J, Klaus Wimmers, Marcus W Feldman, OORTWIJN, M., Crooijmans, Richard P.M.A., Martien A.M. Groenen, Mäki-Tanila Asko, Valery M. Kirzhner, Vignal Alain, Mäki-Tanila, Asko, Freidlin, Paul J., Martien AM Groenen, Crooijmans, Richard P. M. A., Abraham B Korol, Groenen, M.A.M., Valery M Kirzhner, Wimmers, Klaus, Kirzhner, V.M., Fieldman, M.W., Tixier-Boichard, M., Barre-Dirie, A., Elo, K., Feldman, Marcus W, Vignal, Alain, Crooijmans, R.P.M.A., David Lior, Wimmers Klaus, Asko M�ki-Tanila, Groenen, Martien A. M., Paul J Freidlin, Mich�le Tixier-Boichard, Oortwijn, Marian, Freidlin, P.J., David, L., Thomson, Pippa, Groenen, Martien A.M., Steffen Weigend, Maki-Tanila, A., WIMMERS, K., Hillel Jossi, Asili Barre-Dirie, Paul J. Freidlin, Weigend Steffen, Marian Oortwijn, Oortwijn Marian, Tixier-Boichard Michèle, Hillel, J., Groenen Martien AM, Jossi Hillel, Feldman, M., Asko Mäki-Tanila, Tixier-Boichard, Michèle, Abraham B. Korol, Elo Kari, Hillel, Jossi, Terry Burke, Elo, Kari, THOMSON, P., Richard P.M.A. Crooijmans, David, Lior, Feldman, Marcus W., Thomson Pippa, Groenen, Martien A M, Crooijmans, Richard P M A, Korol Abraham B, Korol, A.B., Richard PMA Crooijmans, Barre-Dirie Asili, Vignal, A., Oortwijn, M.E.P., Alain Vignal, Lior David, Crooijmans Richard PMA, Burke Terry   +92 more
core   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Crystal engineering optimizes emodin-tetramethylpyrazine combination: From cocrystal design to in vivo anti-colitis efficacy assessment

International Journal of Pharmaceutics: X
Emodin (EMO) shows therapeutic promise for ulcerative colitis (UC), yet its clinical utility is hampered by low bioavailability. To rationally overcome this limitation, this study employed cocrystal engineering, strategically selecting ...
Meiru Liu, Yinru Jiang, Penghui Yuan, Shuang Li, Baoxi Zhang, Xia Zhou, Bin Su, Yifei Xie, Dezhi Yang, Linglei Kong, Li Zhang, Yang Lv, Guanhua Du   +12 more
doaj   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh, Dalia Sriwi, Callie Saric, Tripti Singh, Christie M. Bartels, Shivani Garg   +5 more
wiley   +1 more source

On the Pursuit of Static and Coherent Weaving [PDF]

, 2006
Aspect-oriented programming (AOP) has been shown to be a useful model for software development. Special care must be taken when we try to adapt AOP to strongly typed functional languages which come with features like type inference mechanism ...
Chen, Kung, Khoo, Siau-Cheng, Wang, Meng
core  

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Short‐term use of oral amiodarone causing torsades de pointes

Clinical Case Reports, 2018
Key Clinical Message Amiodarone is one of the most commonly used antiarrhythmic drugs. Despite its well‐known side effects, amiodarone is considered to be a relatively safe drug, especially in short‐term usage to prevent life‐threatening ventricular ...
Stephen Yau, Patrick Chan, Joshua Sapkin, Eric Hsieh   +3 more
doaj   +1 more source

Distribution of Polymorphic and Non-Polymorphic Microsatellite Repeats in Xenopus tropicalis

, 2008
The results of our bioinformatics analysis have found over 91,000 di-, tri-, and tetranucleotide microsatellites in our survey of 25% of the X. tropicalis genome, suggesting there may be over 360,000 within the entire genome. Within the X.
Dan E. Wells, Steve Scherer, Amy K. Sater, Zhenkang Xu, Matthew Hitchens, Laura Gutierrez   +5 more
core  

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source