Results 21 to 30 of about 202,025 (268)

Identification of compounds to promote diabetic wound healing based on transcriptome signature

Frontiers in Pharmacology
PurposeDiabetic wounds are characterized by delayed healing, and the resulting diabetic foot ulcer may lead to severe complications, including amputations and mortality.
Jiamin Shang, Zhaoyu Liu, Meidai Liang, Zijie Yin, Zeyu Yang, Xiaomeng Ye, Guanhua Du, Xiuying Yang   +7 more
doaj   +1 more source

Advances in Quantitative Analytical Methods for Solid Drugs

Crystals
The solid form of the drug can directly affect the physicochemical properties, bioavailability, safety, and efficacy of the drug, and its types mainly include amorphous state, single-component polycrystalline, hydrate, solvate, salt, and cocrystal ...
Yue Tao, Yuhan Gao, Baoxi Zhang, Kun Hu, Yifei Xie, Li Zhang, Shiying Yang, Yang Lu   +7 more
doaj   +1 more source

A Hybrid SRAM/RRAM In-Memory Computing Architecture Based on a Reconfigurable SRAM Sense Amplifier

IEEE Access, 2023
In this paper, a hybrid memory architecture based on a new array of SRAM and resistive random-access memory (RRAM) cells is proposed to perform in-memory computing by implementing all basic two-input Boolean functions. The SRAM array can be configured as
Seyed Hassan Hadi Nemati, Nima Eslami, Mohammad Hossein Moaiyeri   +2 more
doaj   +1 more source

Pharmacological agents for promoting diabetic wound healing

Acta Pharmaceutica Sinica B
Diabetic wounds are highly susceptible to chronicity and infection due to impaired healing involving multiple pathophysiological factors. Despite extensive preclinical and clinical research, few approved drugs have been shown to effectively accelerate ...
Jiamin Shang, Zhaoyu Liu, Meidai Liang, Xiaomeng Ye, Zijie Yin, Zeyu Yang, Jiaqi Zhao, Hongjing Wu, Guanhua Du, Xiuying Yang   +9 more
doaj   +1 more source

Bifid Shape Is Intrinsic to Bifidobacterium adolescentis

Frontiers in Microbiology, 2017
Although the genus Bifidobacterium was originally named for its bifid morphology, not all bifidobacterial species have a similar structure, and very few of them adopt a bifid shape under stress conditions.
Dhanashree, Sharika Rajashekharan, Balamurugan Krishnaswamy, Rajagopal Kammara   +3 more
doaj   +1 more source

Biochemical characterization of the Nigerian indigenous guinea fowl (Numida meleagris) [PDF]

Biotechnology in Animal Husbandry, 2016
Blood protein polymorphism has been extensively used for characterization and estimation of genetic diversity in farm animals. A study on biochemical characterization and estimation of genetic diversity of Nigerian indigenous guinea fowls (Numida ...
Oguntunji Olusegun Abel, Ayorinde Luke Kolawole, Aremu Olayemi Taiwo   +2 more
doaj  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Enhanced thermoelectric performance in polymorphic heavily Co-doped Cu2SnS3 through carrier compensation by Sb substitution

Science and Technology of Advanced Materials, 2021
Heavily acceptor-doped Cu2SnS3 (CTS) shows promisingly large power factor (PF) due to its rather high electrical conductivity (σ) which causes a modest ZT with a high electronic thermal conductivity (κe).
Yaqing Zhao, Yan Gu, Peng Zhang, Xiaohui Hu, Yifeng Wang, Peng’An Zong, Lin Pan, Yinong Lyu, Kunihito Koumoto   +8 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Enhancing Solubility and Dissolution Rate of Antifungal Drug Ketoconazole through Crystal Engineering

Pharmaceuticals, 2023
To improve the solubility and dissolution rate of the BCS class II drug ketoconazole, five novel solid forms in 1:1 stoichiometry were obtained upon liquid-assisted grinding, slurry, and slow evaporation methods in the presence of coformers, namely ...
Hongmei Yu, Li Zhang, Meiju Liu, Dezhi Yang, Guorong He, Baoxi Zhang, Ningbo Gong, Yang Lu, Guanhua Du   +8 more
doaj   +1 more source