Results 201 to 210 of about 444,739 (309)

Manganese Neurotoxicity and Familial Disorders of Manganese Transport

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley   +1 more source

Association of TLR3 1337C/T and 1234C/T polymorphisms with chronic hepatitis B virus infection in Sudanese patients: A case-control study. [PDF]

J Int Med Res
Elyass K, Osman NAM, Gorish BMT, Nail AM, Abdelmula WIY, Khalil Abuzeid NM.   +5 more
europepmc   +1 more source

CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention in the Million Veteran Program

Clinical Pharmacology &Therapeutics, EarlyView.
CYP2C19 loss‐of‐function (LOF) alleles decrease the antiplatelet effect of clopidogrel following percutaneous coronary intervention (PCI) in patients presenting with acute coronary syndrome (ACS). The impact of genotype in patients undergoing PCI for stable ischemic heart disease (SIHD) in real‐world populations is less clear.
Catherine Chanfreau‐Coffinier, Kevin A. Friede, Mary E. Plomondon, Kyung Min Lee, Zhenyu Lu, Tia Dinatale, Scott L. DuVall, Jason L. Vassy, Stephen W. Waldo, John H. Cleator, Thomas M. Maddox, Daniel J. Rader, Themistocles L. Assimes, Scott M. Damrauer, Philip S. Tsao, Kyong‐Mi Chang, Deepak Voora, Julie A. Lynch, Jay Giri, VA Million Veteran Program, Sony Tuteja   +20 more
wiley   +1 more source

Association Between Dysmenorrhea and Endometrial Cancer: A Mendelian Randomization Study. [PDF]

Pain Res Manag
Huang Q, Huang X, Huang L, Wang Y, Li S, Zheng X.   +5 more
europepmc   +1 more source

Intestinal Barrier Glycosylation for Gut Physiology and Pathology

Barrier Immunity, EarlyView.
ABSTRACT The intestinal barrier is a selective structure that safeguards the body from external threats while permitting nutrient absorption and immune surveillance. It consists of the outer mucus layer, the intermediate layer of intestinal epithelial cells (IECs), and the inner layer of immune cells. The proteins in the mucus layer and within IECs are
Girak Kim, Deji Ye, Yikun Yao, Chuan Wu
wiley   +1 more source

Correction: Single Nucleotide Polymorphism Analysis of European Archaeological DNA.

PLoS ONE, 2010
Claire L. Watson, Elizabeth Popescu, Jesper Boldsen, Mario Slaus, Diana N. J. Lockwood   +4 more
doaj   +1 more source

Loss of the epithelial transcription factor grhl3 leads to variably penetrant developmental phenotypes in zebrafish

Developmental Dynamics, EarlyView.
Abstract Background Environmental influence is critical for embryogenesis but is significantly under‐appreciated under lab conditions, which are not typically designed to robustly test environmental variability. Here, we report environmental effects on the developmental phenotype of zebrafish lacking the transcription factor Grainyhead‐like 3 (grhl3 ...
Nishanthi Mathiyalagan, Travis K. Johnson, Zachary Di Pastena, Jarrad N. Fuller, Lee B. Miles, Sebastian Dworkin   +5 more
wiley   +1 more source

LncRNA <i>C5orf64</i> polymorphisms (rs12518552 and rs2950218) decreases pulmonary tuberculosis susceptibility. [PDF]

Ann Med
Xu S, Hu B, Zhang D, Wang J, He X, He Y, Wang Y.   +6 more
europepmc   +1 more source

Single‐cell‐eQTL mapping in circulating immune cells reveals genetic regulation of response‐associated networks in lung cancer immunotherapy

Cancer Communications, EarlyView.
Hyungtai Sim, Geun‐Ho Park, Woong‐Yang Park, Se‐Hoon Lee, Murim Choi   +4 more
wiley   +1 more source

Predictors of Anorexia Nervosa and Obsessive‐Compulsive Disorder Comorbidity and Order of Diagnosis in a Danish National Cohort

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) and obsessive‐compulsive disorder (OCD) are highly comorbid; however, limited research has examined etiological pathways specific to individuals with AN developing OCD or individuals with OCD developing AN. This exploratory study aimed to identify factors influencing AN‐OCD comorbidity with a focus on the order ...
Lisa Yujia Zhu, Janne Tidselbak Larsen, Judith Becker Nissen, James J. Crowley, Manuel Mattheisen, Cynthia M. Bulik, Liselotte Vogdrup Petersen, Zeynep Yilmaz   +7 more
wiley   +1 more source