Results 221 to 230 of about 690,386 (352)

Approaches to repurposing reverse transcriptase antivirals in cancer

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head   +2 more
wiley   +1 more source

A Common Single Nucleotide Polymorphism Can Exacerbate Long-QT Type 2 Syndrome Leading to Sudden Infant Death

open access: yesCirculation: Cardiovascular Genetics, 2010
E. Nof   +9 more
semanticscholar   +1 more source

Generation of Clonal Cultures of Adherent or Suspension Cells Using Flat Sessile Drops for Assurance of Monoclonality

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Single‐cell isolation is an essential step in many biomedical workflows, including genetic analyses and drug‐based assays. It is commonly attempted through limiting dilution into microtiter wells. However, dark optical edge effects at the well periphery make it difficult to confirm which wells contain just one cell.
Joseph A. E. Morgan   +3 more
wiley   +1 more source

Pan‐cancer analysis shapes the understanding of cancer biology and medicine

open access: yesCancer Communications, EarlyView.
Abstract Advances in multi‐omics datasets and analytical methods have revolutionized cancer research, offering a comprehensive, pan‐cancer perspective. Pan‐cancer studies identify shared mechanisms and unique traits across different cancer types, which are reshaping diagnostic and treatment strategies.
Xiaoping Cen   +21 more
wiley   +1 more source

Reply

open access: yes
Arthritis &Rheumatology, EarlyView.
Jie Zheng   +2 more
wiley   +1 more source

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