Results 221 to 230 of about 715,750 (339)

The role of Rho GTPases in facial morphogenesis

Developmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Molecular markers associated with elevated colorectal cancer risk: a mini review. [PDF]

Hered Cancer Clin Pract
Szuman M, Kazimierczyk M, Grot N, Kaczmarek-Ryś M, Kryszczyńska A, Dziechciowska I, Knaur M, Hnatyszyn A, Hryhorowicz S, Pławski A.   +9 more
europepmc   +1 more source

Efficient parentage assignment and pedigree reconstruction with dense single nucleotide polymorphism data.

Journal of Dairy Science, 2011
B. Hayes
semanticscholar   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

ESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu, Gui‐Qin Liu, Ya‐Ping Peng, Li‐Ling Zhang, Xian‐Jin Wang, Liang‐Chuan Chen, Yuan‐Xi Zheng, Xue‐Jun Xiang, Rui Qiao, Xian‐He Lin   +9 more
wiley   +1 more source

Development and application of a multiple nucleotide polymorphism (MNP)-based molecular identification system for pear cultivars. [PDF]

BMC Plant Biol
Yang X, Fang Z, Cao Y, Tian L, Peng H, Zhang Y, Xu J, Zhou J, Huo H, Qi D, Liu C, Li T, Dong X.   +12 more
europepmc   +1 more source

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Association of angiotensin-converting enzyme 2 gene polymorphisms with hypertension and treatment response to hydroxychloroquine in Iranian people with coronavirus disease 2019: A cross-sectional study. [PDF]

J Int Med Res
Jafary F, Kazemi M, Zarean M, Khoshhali M, Karimian M, Fani F, Shahzamani K.   +6 more
europepmc   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk, Christopher Faulk, Jessica LaRocca, Jan van Benthem, Francesco Marchetti   +4 more
wiley   +1 more source

Construction of a Risk Factor Model for Wound Infection After Ileostomy for Rectal Cancer and Its Relationship with Nucleotide-Binding Oligomerization Domain-Like Receptor Protein 3 (NLRP3) Gene Polymorphism. [PDF]

Infect Drug Resist
Li Y, Zhou Y, Wang F, Shi P, Yang J, Zhang B, Shi R, Wei M, Ren H.   +8 more
europepmc   +1 more source

Transcript-specific, single-nucleotide polymorphism discovery and linkage analysis in hexaploid bread wheat (Triticum aestivum L.).

Plant Biotechnology Journal, 2011
A. Allen, G. Barker, S. Berry, J. Coghill, R. Gwilliam, S. Kirby, P. Robinson, Rachel Brenchley, Rosalinda D'Amore, N. McKenzie, D. Waite, Anthony Hall, M. Bevan, N. Hall, K. Edwards   +14 more
semanticscholar   +1 more source