Results 101 to 110 of about 727,358 (304)
The algebraic dichotomy conjecture for infinite domain Constraint Satisfaction Problems
, 2016 We prove that an $\omega$-categorical core structure primitively positively interprets all finite structures with parameters if and only if some stabilizer of its polymorphism clone has a homomorphism to the clone of projections, and that this happens if
Barto L., Bodirsky M., Hodges W.
core +1 more source
Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome‐wide association studies (GWAS) for impact on cerebrospinal fluid (CSF) proteins reflecting lysosomal function.
Hanwen Zhang +16 more
wiley +1 more source
Frontiers in Behavioral Neuroscience, 2009 Variations of the corticotropin-releasing hormone receptor 1 (CRHR1) gene appear to moderate the development of depression after childhood trauma. Depression more frequently affects women than men.
Christine Heim +11 more
doaj +1 more source
Il-4 Polymorphism in Patients with Acute Brucellosis in the Republic of Azerbaijan [PDF]
, 2018 Currently, there are isolated data on the relationship between IL-4 polymorphism (C-589T) and susceptibility to brucellosis. Therefore, the purpose of the study was to determine the frequency of polymorphism of IL-4 (C-589T) in patients with acute ...
Huseynov, E. M. (Elchin)
core
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie +4 more
wiley +1 more source
Relationship of cognitive decline with glucocerebrosidase activity and amyloid‐beta 42 in DLB and PD
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Dementia with Lewy bodies (DLB) and Parkinson's disease (PD) share clinical, pathological, and genetic risk factors, including GBA1 and APOEε4 mutations. Biomarkers associated with the pathways of these mutations, such as glucocerebrosidase enzyme (GCase) activity and amyloid‐beta 42 (Aβ42) levels, may hold potential as predictive ...
Maria Camila Gonzalez +15 more
wiley +1 more source
Snails in the sun: Strategies of terrestrial gastropods to cope with hot and dry conditions
Ecology and Evolution, 2019 Terrestrial gastropods do not only inhabit humid and cool environments but also habitat in which hot and dry conditions prevail. Snail species that are able to cope with such climatic conditions are thus expected to having developed multifaceted ...
Mona Schweizer +2 more
doaj +1 more source
Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi +7 more
wiley +1 more source
A Straightforward Method to Judge the Completeness of a Polymorphic Gate Set [PDF]
arXiv, 2017 Polymorphic circuits are a special kind of circuits which possess some different build-in functions and these functions are activated by environment parameters, like light and VDD. Some theories have been proposed to guide the design of polymorphic circuits, including the definition of complete polymorphic gate sets and algorithms to judge the ...
arxiv
Abnormal Synchronization Between Cortical Delta Power and Ripples in Hippocampal Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Discriminating between epileptogenic and physiological ripples in the hippocampus is important for identifying epileptogenic (EP) zones; however, distinguishing these ripples on the basis of their waveforms is difficult. We hypothesized that the nocturnal synchronization of hippocampal ripples and cortical delta power could be used ...
Takamitsu Iwata +10 more
wiley +1 more source