Results 61 to 70 of about 837,662 (281)

FABP-2 and PPAR-γ Haplotype as Risk Factors for Dyslipidemia in a Type 2 Diabetes Mellitus Population of Santa Rosa del Conlara, San Luis, Argentina [PDF]

, 2014
Introduction: Type 2 Diabetes Mellitus (T2DM) is a complex disorder caused by the interaction between genetic predisposition and environmental factors. Genetics plays an important role on lipid homeostasis. Many genes are involved in the lipid metabolism,
Fernandez, Gustavo, Gonzalez, Irma Ines, Ojeda, Marta Susana, Olmos Nicotra, Maria Florencia, Siewert, Susana Elfrida   +4 more
core   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Inflammatory markers of vascular wall in native population of Nenets autonomous district

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2016
Study of inflammatory markers of vascular wall in nenets population showed access of adopted reference values that can indicate serious violations of hemostasis system. However, apparent increase of inflammatory markers of vascular wall in blood can also
N. I. Belova, N. A. Vorobyova
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Tumor necrosis factor alpha gene polymorphism in Serbian patients with sarcoidosis [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2013
Introduction. Sarcoidosis is a multisystemic disease of unknown etiology. Genetic factors play a considerable role in the onset of the disease. Tumor necrosis factor alpha (TNF-α) is a proinflammatory cytokine which plays an important role in the ...
Rađenović-Petković Tatjana, Pejčić Tatjana, Videnović-Ivanov Jelica, Jevtović-Stoimenov Tatjana, Janković Irena, Nastasijević-Borovac Desa, Radojković Danijela   +6 more
doaj   +1 more source

POLYMORPHISM AND POLYMORPH CHARACTERISATION IN PHARMACEUTICALS

Journal of Biomedical and Pharmaceutical Research, 2019
Polymorphism is the ability of a specific chemical compound to crystallize in more than one crystalline form. Polymorphs had a different arrangement of the molecule in the given crystal lattice and  may properties such as packing properties, thermodynamic properties, spectroscopic properties, kinetic properties, surface properties and mechanical ...
Dr Amit Gosar, Dr Sayyed Hussain, Dr Tabrez Shaikh   +2 more
openaire   +2 more sources

PPAR gamma pro12Ala polymorphism and type 2 diabetes: a study in a spanish cohort [PDF]

, 2014
Type 2 diabetes (T2D) is a disease whose occurrence is increasing prevalent in westernized civilizations and is responsible for the proliferation in the morbidity and total mortality of patients with cardiovascular diseases, worldwide.
Cieza Borrella, C, Corral Gudino, L, González Sarmiento, R, Makena Hoghtower, C, Mayoral, R, Miramontes González, JP   +5 more
core   +1 more source

RAB39B Related Parkinsonism in an Italian Family: A Unique Use of Advanced Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Parkinson's disease (PD) is a neurodegenerative disorder that may sometimes be caused by deleterious genetic variants. Among them, RAB39B polymorphisms are known as rare causes of early‐onset PD associated with intellectual disability (Waisman's syndrome).
Caterina Del Regno, Giovanni Ermanis, Christian Lettieri, Andrea Bernardini, Gaia Pellitteri, Enrico Belgrado, Elena Betto, Gian Luigi Gigli, David De Monte, Marco Domenico Scanni, Marco Mucchiut, Giuseppe Damante, Mariarosaria Valente, Francesco Janes   +13 more
wiley   +1 more source

Genomic investigation of NDM-1 producing Enterobacterales transmission in a South Korean hospital

Journal of Global Antimicrobial Resistance
Objective: Prolonged detection of multispecies New Delhi metallo-β-lactamase (NDM)-1-producing Enterobacterales was observed in front of a South Korean hospital.
Jeong-Ih Shin, Sun Hee Park, Chulmin Park, Seung-Hyun Jung, Dong-Gun Lee   +4 more
doaj   +1 more source

Relationship analysis of TNF and IL8 gene polymorphisms with clinical features of chronic obstructive pulmonary disease

Бюллетень сибирской медицины, 2010
The correlation of the 308G/A polymorphism of α TNF (tumor necrosis factor) gene and 251А/Т polymorphism of 8 IL8 (interleukin 8) gene with clinical peculiarities of the course of chronic obstructive lung disease (COLD) in Siberian Tatars and Russians ...
G. N. Seitova, Ye. B. Bukreyeva, I. S. Kremis, V. P. Puzyryov   +3 more
doaj   +1 more source