Results 1 to 10 of about 858,337 (137)

Identification of gene candidates associated with Irritable bowel syndrome [PDF]

Scripta Medica, 2022
Background/Aim: Irritable bowel syndrome (IBS) belongs to the gastrointestinal disorders characterised by abdominal discomfort and pain, altered constipation, diarrhoea and stomach distension.
Milovac Irina, Vidović Vanja, Ramić Jasmin, Lojo-Kadrić Naida, Hadžić Maida, Mavija Zoran, Vidović Stojko, Pojskić Lejla   +7 more
doaj   +1 more source

Association of CNR1 and INSIG2 polymorphisms with antipsychotics-induced weight gain: a prospective nested case–control study

Scientific Reports, 2021
Weight gain is a frequent and severe adverse reaction in patients taking antipsychotics. The objective was to further investigate in a natural setting influential risk factors associated with clinically significant weight gain. An observational follow-up
Natalia Jimeno, Veronica Velasco-Gonzalez, Inmaculada Fierro, Mercedes Duran, Alfonso Carvajal   +4 more
doaj   +1 more source

Association of vitamin D receptor gene polymorphisms with rheumatoid arthritis

Archives of Medical Science, 2021
Introduction Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease of unknown etiology which causes progressive deterioration of the joints, leading to severe pain and functional disability.
Noelia Marquez Pete, Cristina Perez Ramirez, Maria del Mar Maldonado Montoro, Fernando Martinez Martinez, Fernando Fernández-Llimos, Antonio Sánchez Pozo, María del Carmen Ramirez Tortosa, Alberto Jiménez Morales   +7 more
doaj   +1 more source

Differential Effect of Polymorphisms on Body Mass Index Across the Life Course of Japanese: The Japan Multi-Institutional Collaborative Cohort Study

Journal of Epidemiology, 2021
Background: Obesity is a reported risk factor for various health problems. Genome-wide association studies (GWASs) have identified numerous independent loci associated with body mass index (BMI). However, most of these have been focused on Europeans, and
Madoka Iwase, Keitaro Matsuo, Masahiro Nakatochi, Isao Oze, Hidemi Ito, Yuriko Koyanagi, Tomotaka Ugai, Yumiko Kasugai, Asahi Hishida, Kenji Takeuchi, Rieko Okada, Yoko Kubo, Chisato Shimanoe, Keitaro Tanaka, Hiroaki Ikezaki, Masayuki Murata, Toshiro Takezaki, Daisaku Nishimoto, Nagato Kuriyama, Etsuko Ozaki, Sadao Suzuki, Miki Watanabe, Haruo Mikami, Yohko Nakamura, Hirokazu Uemura, Sakurako Katsuura-Kamano, Kiyonori Kuriki, Yoshikuni Kita, Naoyuki Takashima, Masato Nagino, Yukihide Momozawa, Michiaki Kubo, Kenji Wakai   +32 more
doaj   +1 more source

Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population. [PDF]

, 2014
One-carbon metabolism (folate metabolism) is considered important in carcinogenesis because of its involvement in DNA synthesis and biological methylation reactions.
Baecker, Aileen, Butler, Brendan, Cai, Lin, Chang, Po-Yin, Chang, Shen-Chih, Goldstein, Binh Y, Greenland, Sander, Heber, David, Li, Liming, Lu, Qing-Yi, Mu, Lina, You, Nai-Chieh Y, Yu, Shun-Zhang, Zhang, Zuo-Feng   +13 more
core   +12 more sources

HLA and Non-HLA gene polymorphisms in autoimmune hepatitis patients of North Indian adults

Frontiers in Immunology, 2023
Autoimmune hepatitis (AIH) is a chronic and progressive disease of the liver. This is a multifactorial autoimmune disease with both environmental factors and genetic factors playing a role in its pathogenesis.
Nishtha Ahuja, Jagdeep Singh, Ranjana Walker Minz, Shashi Anand, Ashim Das, Sunil Taneja   +5 more
doaj   +1 more source

Pharmacogenetics of ophthalmic topical β-blockers [PDF]

, 2008
Glaucoma is the second leading cause of blindness worldwide. The primary glaucoma risk factor is elevated intraocular pressure. Topical β-blockers are affordable and widely used to lower intraocular pressure.
McCarty, Catherine A., Patchett, Richard, Sidjanin, Duska J., Smith, Edward M., Wilke, Russell A.   +4 more
core   +1 more source

Spreading maps (polymorphisms), symmetries of Poisson processes and matching summation [PDF]

, 2001
The matrix of a permutation is a partial case of Markov transition matrices. In the same way, a measure preserving bijection of a space A with finite measure is a partial case of Markov transition operators.
Neretin, Yurii A.
core   +4 more sources

FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls—The GEA Mexican Study

Biomolecules, 2022
FOXA3 is a transcription factor involved in the macrophage cholesterol efflux and macrophage reverse cholesterol transport reducing the atherosclerotic lesions.
Gilberto Vargas-Alarcón, José Manuel Fragoso, Julian Ramírez-Bello, Rosalinda Posadas-Sánchez   +3 more
doaj   +1 more source

Insulin gene polymorphisms in type I diabetes, Addison's disease and the polyglandular autoimmune syndrome type II [PDF]

, 2008
Background: Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from ß-cell ...
Badenhoop, Klaus, Hahner, Stefanie, Kahles, Heinrich, Lange, Britta Kristina, Meyer, Gesine, Penna Martinez, Marissa, Ramos-Lopez, Elizabeth, Reisch, Nicole, Seissler, Jürgen, Willenberg, Holger S.   +9 more
core   +2 more sources