Results 31 to 40 of about 858,486 (284)
Circulation Research, 2006 Angiotensin converting enzyme (ACE) plays an essential role in two physiological systems, one leading to the production of angiotensin II and the other to the degradation of bradykinin. The wide distribution and multifunctional properties of these peptides suggest that ACE could be involved in various pathophysiological conditions.
Sayed-Tabatabaei, FA (Fakhredin) +4 more
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Frontiers in Genetics, 2012 Cancer is a leading cause of death worldwide. The cancer incidence rate in Chile is 133.7/100,000 inhabitants and it is the second cause of death, after cardiovascular diseases.
Angela Margarita Roco +15 more
doaj +1 more source
Significant correlation of angiotensin converting enzyme and glycoprotein IIIa genes polymorphisms with unexplained recurrent pregnancy loss in north of Iran [PDF]
, 2016 Background: Spontaneous abortion is considered as the most complex problem during pregnancy. Thrombophilia is resumed as a cause of recurrent pregnancy loss (RPL). Glycoprotein IIIa (GPIIIa) gene is involved in thrombosis and abortion.
Farazmandfar, T. +2 more
core +1 more source
Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population
Molecular Genetics & Genomic Medicine, 2021 Background Cytochrome P450 (CYP2B6) is an important enzyme that metabolizes about 3.0% of therapeutic drugs. Drugs metabolized mainly by CYP2B6 include artemisinin, bupropion, cyclophosphamide, efavirenz, ketamine, and methadone.
Sagheer Ahmed +4 more
doaj +1 more source
The influence of 5-HT(2C) and MDR1 genetic polymorphisms on antipsychotic-induced weight gain in female schizophrenic patients [PDF]
, 2008 We investigated the relationships between functional genetic variants of the 5-HT(2C) receptor and multidrug-resistant protein (MDR1), coding for P-glycoprotein, and second generation antipsychotic (SDA)-induced weight gain among 108 female schizophrenic
Bilušić, Hrvoje +5 more
core +1 more source
Genetic study in patients operated dentally and anesthetized with articaine-epinephrine [PDF]
, 2019 Aims: In this study we wanted to figure out if there was a correlation between OPRM1 N40D, TRPV1 I316M, TRPV1 I585V, NOS3 −786T>C and IL6 −174C>G polymorphisms and the response to locally applied articaine-epinephrine anesthetic.
Cieza-Borrella, C +5 more
core +2 more sources
H5N1 Clade 2.2 Polymorphism Tracing Identifies Influenza Recombination and Potential Vaccine Targets [PDF]
, 2007 Highly pathogenic Influenza A H5N1 was first identified in Guangdong Province in 1996, followed by human cases in Hong Kong in 1997 1. The number of confirmed human cases now exceeds 300 and the associated Case Fatality Rate exceeds 60% 2.
A Abdelghani +15 more
core +3 more sources
Advanced Biomedical Research, 2016 Background: Variations in the hepatic lipase (HL) gene are the potential candidate for coronary artery disease (CAD) especially in type 2 diabetes mellitus (T2DM) in diverse populations. We assessed the association of -514C/T and -250G/A polymorphisms in
Ghorban Mohammadzadeh +3 more
doaj +1 more source
A four-month gatifloxacin-containing regimen for treating tuberculosis. [PDF]
, 2014 BACKGROUND: Shortening the course of treatment for tuberculosis would be a major improvement for case management and disease control. This phase 3 trial assessed the efficacy and safety of a 4-month gatifloxacin-containing regimen for treating rifampin ...
Amukoye, Evans +19 more
core +1 more source
Disappearing Polymorphs Revisited [PDF]
Angewandte Chemie International Edition, 2015 AbstractNearly twenty years ago, Dunitz and Bernstein described a selection of intriguing cases of polymorphs that disappear. The inability to obtain a crystal form that has previously been prepared is indeed a frustrating and potentially serious problem for solid‐state scientists.
Bucar, D, Lancaster, RW, Bernstein, J
openaire +3 more sources