Results 111 to 120 of about 43,976 (255)

Intravesical therapy for recurrent urinary tract infection: a systematic review and meta‐analysis

BJU International, Volume 138, Issue 1, Page 33-44, July 2026.
Objective To undertake a systematic review and meta‐analysis to evaluate the efficacy, safety, and clinical applicability of intravesical instillations for preventing recurrent urinary tract infections (rUTIs). Methods PubMed/MEDLINE, Embase, Cochrane CENTRAL, Scopus, and Web of Science were searched from January 2000 to April 2025 for randomised and ...
Matthew Kwon, Asaad Ahmad, Natalie Lott, Alison Blatt   +3 more
wiley   +1 more source

Data_Sheet_1_Purification, Characterization and in vitro Evaluation of Polymyxin A From Paenibacillus dendritiformis: An Underexplored Member of the Polymyxin Family.pdf

, 2018
Nosocomial infections caused by antibiotic-resistant Gram-negative pathogens are of grave concern today. Polymyxins are considered as the last resorts of therapy to treat these multi-drug resistant (MDR) bacteria.
Pallavi Jaswal (6003782), Harmandeep Kaur Randhawa (6003770), Ashish Arora (210036), Prashant P. Patil (6003779), Prabhu B. Patil (179402), Manpreet Kaur (408170), Anugya Srivastava (6003773), Navdezda Maurya (6003776), Hemraj Nandanwar (6003785), Manoj Jangra (6003767), Manoj Raje (586808)   +10 more
core   +1 more source

Antibiotics in Veterinary Ophthalmology: Resistance, Stewardship, and Emerging Antibiotic‐Sparing Strategies

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Antimicrobial resistance (AMR) is a growing challenge in veterinary ophthalmology, particularly in cases of bacterial keratitis, where progressive stromal infection can threaten vision and globe integrity within hours to days. This review synthesizes current evidence on pathogen distribution, antimicrobial susceptibility profiles, multidrug ...
Lionel Sebbag, Oren Pe'er
wiley   +1 more source

Polymyxin Including Therapy Versus Colistin Including Therapy In The Therapy Of Carbapenem-Resistant Gram-Negative Infections: A Retrospective Matched Cohort Study

Journal of Global Antimicrobial Resistance
BACKGROUND-AIM: In this retrospective matched cohort study, we aimed to compare the clinical outcomes of polymyxin b (PMXB) including therapy receiving cases with colistin receiving cases on culture-proven carbapenem-resistant Gram-negative infections ...
Merve Mert Vahabi, Deniz Akyol, Olcay Buse Kenanoğlu, Gamze Şanlıdağ, Şevket Yeniyol, Deniz Dağ, Cansu Bulut Avşar, Ayşe Önal, Şükrü Dirik, Meltem Tüğdür, Uğur Önal, Gökhan Vatansever, Seichan Ketentzi, Arda Kaya, Oğuzhan Acet, Nazlıhan Yalçın, Buğra Özkara, Hilal Sipahi, Bilgin Arda, Oğuz Reşat Sipahi   +19 more
doaj   +1 more source

Topical Mitomycin C Chemotherapy After Surgical Resection of Conjunctival Amelanotic Melanoma in a Dog

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To describe the clinical course and outcome of adjuvant topical mitomycin C (MMC) therapy following incomplete resection of a conjunctival amelanotic melanoma in a dog. Animals Studied A 15‐year‐old spayed‐female Shih Tzu presented with a conjunctival mass in the right eye (OD).
Junyeong Ahn, Koangyong Sung, Minwoo Jang, Kangmoon Seo, Seonmi Kang   +4 more
wiley   +1 more source

Biofilm and surface-motility profiles under polymyxin B stress in multidrug-resistant KAPE pathogens isolated from Ghanaian hospital ICUs

Experimental Biology and Medicine
The threat of antimicrobial resistance in Ghana is increasing with the recent emergence of KAPE pathogens (K. pneumoniae, A. baumannii, P. aeruginosa and Enterobacter species) from the hospital environment.
Molly K. Abban, Molly K. Abban, Eunice Ampadubea Ayerakwa, Eunice Ampadubea Ayerakwa, Abiola Isawumi, Abiola Isawumi   +5 more
doaj   +1 more source

Clinical Features and Surgical Outcomes of Cats With Presumed Primary Lens Instability: A Retrospective Study of 34 Cases (2018–2022)

Veterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective Describe the clinical features, disease progression, and outcomes of presumed primary lens instability (PLI) in cats, and to assess its association with glaucoma. Animals Studied Thirty‐four cats (68 eyes). Procedures Medical records were reviewed for signalment, clinical history, ophthalmic findings, and treatment.
Havi Sarfaty, Raaya Ezra‐Elia, Nili Kahane, Shai Sandalon, Yifat Segev, Lionel Sebbag   +5 more
wiley   +1 more source

Structure−Activity Relationships of Polymyxin Antibiotics

, 2016
Structure−Activity Relationships of Polymyxin ...
Jian Li (41607), Philip E. Thompson (1374795), Tony Velkov (1315626), Roger L. Nation (1315620)   +3 more
core   +1 more source

Guidelines for Comparing Circular Dichroism Spectroscopy and Molecular Dynamics Simulations for Biomolecules

ChemPhysChem, Volume 27, Issue 12, 26 June 2026.
A direct comparison is made between circular dichroism (CD) spectroscopy and molecular dynamics (MD) simulations for studying peptide partitioning through biological membranes. The assumptions and limitations of each method is discussed, and case studies are provided for their use.
Cinzia Campus, Marta Roldo, Charles H. Chen, Roja Hadianamrei, Elisabetta Gavini, Christian Jorgensen   +5 more
wiley   +1 more source

Optimisation of a Novel Class of DNA Gyrase Inhibitors to Improve Antibacterial Activity

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
This article describes efforts to increase the antibacterial activity of a recently reported class of novel DNA gyrase inhibitors known as the isoquinoline sulphonamides by improving their uptake in bacterial cells. As antibiotic resistance continues to rise, the need for new antibacterials is clear.
Meg I. Ferguson, Cerissa C. van Walstijn, Vladyslav Lysenko, Marta A. Wilbrink, David Alencar Araripe, Jeroen M. Punt, Mario van der Stelt, Willem Jespers, Paolo Innocenti, Nathaniel I. Martin   +9 more
wiley   +1 more source