Results 91 to 100 of about 7,789 (207)

Complications and outcomes of standing flank versus ventral midline laparotomy for equine nephrosplenic entrapment

open access: yesEquine Veterinary Education, Volume 38, Issue 10, Page e736-e743, October 2026.
Summary Background Nephrosplenic entrapment (NSE) is a common surgical colic in horses. Ventral midline laparotomy (VML) under general anaesthesia (GA) is the standard approach, whereas standing flank laparotomy (SFL) is an alternative approach for surgical correction. However, direct comparisons between these approaches are lacking.
V. Santalucia   +5 more
wiley   +1 more source

Molecular Mechanism of Polymyxin Resistance in Multidrug-Resistant Klebsiella pneumoniae and Escherichia coli Isolates from Henan Province, China: A Multicenter Study

open access: yesInfection and Drug Resistance, 2021
Wenjuan Yan,1,* Qi Zhang,1,* Yingjie Zhu,1 Nan Jing,1 Youhua Yuan,1 Yi Zhang,2 Siying Ren,3 Dongmei Hu,4 Wenmin Zhao,5 Xiaojuan Zhang,6 Caiqin Shi,7 Meiyun Wang,8 Yi Li1 1Department of Clinical Microbiology, Henan Provincial People’s Hospital ...
Yan W   +12 more
doaj  

Prevalence of Antimicrobial Use in Small Animal Dermatology Referral Practices in the United States

open access: yesVeterinary Dermatology, Volume 37, Issue 5, Page 581-591, October 2026.
ABSTRACT Background Antimicrobial resistance is a critical global health concern driven by antimicrobial use. Dermatological conditions are common reasons for antimicrobial prescriptions in small animal practice, yet data on prescribing patterns in veterinary dermatology referral settings are lacking. Hypothesis/Objectives To characterise the frequency,
Domenico Santoro   +2 more
wiley   +1 more source

Treatment Choices for Acute Canine Otitis Externa in Sweden, Finland and Norway: A Comparative Study With a Focus on Antibiotic Use

open access: yesVeterinary Dermatology, Volume 37, Issue 5, Page 806-817, October 2026.
Background: Canine otitis externa (COE) is one of the most frequently recorded disorders in veterinary practices, making it an important focus for antibiotic stewardship. Hypothesis/Objectives: To investigate and compare treatment regimens for acute COE in Finland, Norway and Sweden, with a focus on antibiotic use.
Kaisa Saarinen   +4 more
wiley   +1 more source

Real-world data on the effects of colistin sulfate and polymyxin B sulfate in the treatment of pneumonia induced by CR-GNB

open access: yesJournal of Infection in Developing Countries
Introduction: The aim of this study was to compare the efficacy and safety of colistin sulfate (CS) with polymyxin B sulfate (PMB) in the treatment of pneumonia induced by carbapenem-resistant Gram-negative bacteria (CR-GNB).
Di Liu   +5 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, Volume 38, Issue 51, 11 September 2026.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Polymyxin Including Therapy Versus Colistin Including Therapy In The Therapy Of Carbapenem-Resistant Gram-Negative Infections: A Retrospective Matched Cohort Study

open access: yesJournal of Global Antimicrobial Resistance
BACKGROUND-AIM: In this retrospective matched cohort study, we aimed to compare the clinical outcomes of polymyxin b (PMXB) including therapy receiving cases with colistin receiving cases on culture-proven carbapenem-resistant Gram-negative infections ...
Merve Mert Vahabi   +19 more
doaj   +1 more source

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai   +7 more
wiley   +1 more source

Biofilm and surface-motility profiles under polymyxin B stress in multidrug-resistant KAPE pathogens isolated from Ghanaian hospital ICUs

open access: yesExperimental Biology and Medicine
The threat of antimicrobial resistance in Ghana is increasing with the recent emergence of KAPE pathogens (K. pneumoniae, A. baumannii, P. aeruginosa and Enterobacter species) from the hospital environment.
Molly K. Abban   +5 more
doaj   +1 more source

Identification of a Nonribosomal Peptide Analog With Activity Against Multiple Gram‐Positive Bacteria via a Synthetic Bioinformatic Natural Product Discovery Approach

open access: yesAdvanced Science, Volume 13, Issue 50, 7 September 2026.
The genome of Rhodococcus erythropolis D‐1 was analyzed by bioinformatic tools to mine a novel nonribosomal peptide synthetase (NRPS) gene cluster. A nonribosomal peptide analog ZURJC5 associated with the NRPS was chemically synthesized. Through structure‐activity relationship studies, ZURJC28 was ultimately obtained and showed antibacterial activity ...
Keyi Chen   +9 more
wiley   +1 more source

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