Results 131 to 140 of about 43,976 (255)
Arginine catabolism is essential to polymyxin dependence in Acinetobacter baumannii
Summary: Polymyxins are often the only effective antibiotics against the “Critical” pathogen Acinetobacter baumannii. Worryingly, highly polymyxin-resistant A.
Mei-Ling Han +21 more
core +1 more source
Polymyxin B broth disk elution as a screening test to determine polymyxin B susceptibility in enterobacterales [PDF]
Detection of polymyxins susceptibility by clinical laboratories is a nightmare mainly because of physicochemical properties of the drug. The aim of this study was to evaluate accuracy of Polymyxin B Broth Disk Elution (PBDE), as screening test, compared ...
Cielo, Naiany Canabarro
core
Legionella pneumophila is the principal species responsible for Legionnaires' disease, and measuring microbial load is fundamental to the analysis of environmental water samples. This study compared a new lipopolysaccharide bioprobe method (Microcolony Counter Analysis), which detects and counts L.
Savina Ditommaso +6 more
wiley +1 more source
POLYMYXIN P, NEW ANTIBIOTICS OF POLYMYXIN GROUP
Y, Kimura +4 more
openaire +3 more sources
Pulmonary Target Delivery of Polymyxin B for Enhanced Efficacy
Objective: Polymyxin B is increasingly used as the last resort for multidrug resistant (MDR) Gram-negative bacterial infections. Limited by high polarity of the drug and poor penetration into the pulmonary epithelial lining fluid (ELF), polymyxin B does ...
He, Jie 1981-
core
Surveying 537 farmers in Bangladesh revealed widespread high‐risk antibiotic use, including misuse of critically important antimicrobials and treatment of non‐bacterial diseases. The findings highlight a major knowledge‐practice gap and emphasize the need for improved diagnostics, stronger regulation, and a One Health‐based antimicrobial stewardship ...
Anju Man Ara +3 more
wiley +1 more source
Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi +3 more
wiley +1 more source
On average, phones harbored 3.62 of the top 10 killers and 2.49 ESKAPE organisms. In total, 667 VFGs (8621 Hits) and 262 ARGs (2475 Hits) were identified on 95 mobile phones. Mobile phones serve as a platform for horizontal gene transfer and AMR development.
Adrian Goldsworthy +12 more
wiley +1 more source
Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen +8 more
wiley +1 more source
Antibiotic Resistance and Biofilm Gene Distribution in Colistin‐Resistant Acinetobacter baumannii
Multicenter analysis of 144 clinical Acinetobacter baumannii isolates in Iran revealed high MDR/XDR rates and widespread biofilm formation (90.9%). Colistin resistance was linked to pmrAB overexpression, while blaPER‐1 was independently associated with strong biofilm production, highlighting chromosomal resistance mechanisms and biofilm as key drivers ...
Zainab Amer Hatem +7 more
wiley +1 more source

